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We consider a periodic extension of the classical Kingman non-linear model (Kingman, 1978) for the balance between selection and mutation in a large population. In the original model, the fitness distribution of the population is modeled by…

Probability · Mathematics 2024-05-24 Camille Coron , Olivier Hénard

In the study of natural and artificial complex systems, responses that are not completely determined by the considered decision variables are commonly modelled probabilistically, resulting in response distributions varying across decision…

Methodology · Statistics 2021-10-07 Athénaïs Gautier , David Ginsbourger , Guillaume Pirot

We show how concepts from statistical physics, such as order parameter, thermodynamic limit, and quantum phase transition, translate into biological concepts in mutation-selection models for sequence evolution and can be used there. The…

Statistical Mechanics · Physics 2007-05-23 Joachim Hermisson , Oliver Redner , Holger Wagner , Ellen Baake

The evolution of dispersal is a classical question in evolutionary biology, and it has been studied in a wide range of mathematical models. A selection-mutation model, in which the population is structured by space and a phenotypic trait,…

Analysis of PDEs · Mathematics 2022-05-12 King-Yeung Lam , Yuan Lou , Benoit Perthame

Many complex adaptive systems contain a large diversity of specialized components. The specialization at the level of the microscopic degrees of freedom, and diversity at the level of the system as a whole are phenomena that appear during…

adap-org · Physics 2007-05-23 Vivek S. Borkar , Sanjay Jain , Govindan Rangarajan

We study a nonlinear recombination model from population genetics as a combinatorial version of the Kac-Boltzmann equation from kinetic theory. Following Kac's approach, the nonlinear model is approximated by a mean field linear evolution…

Probability · Mathematics 2024-12-24 Pietro Caputo , Daniel Parisi

We integrate dual-process theories of human cognition with evolutionary game theory to study the evolution of automatic and controlled decision-making processes. We introduce a model where agents who make decisions using either automatic or…

Dynamical Systems · Mathematics 2015-07-07 Danielle F. P. Toupo , Steven H. Strogatz , Jonathan D. Cohen , David G. Rand

Natural selection explains how life has evolved over millions of years from more primitive forms. The speed at which this happens, however, has sometimes defied formal explanations when based on random (uniformly distributed) mutations.…

Neural and Evolutionary Computing · Computer Science 2018-06-22 Santiago Hernández-Orozco , Narsis A. Kiani , Hector Zenil

A probability model is presented for the dynamics of mutation-selection balance in a haploid infinite-population infinite-sites setting sufficiently general to cover mutation-driven changes in full age-specific demographic schedules. The…

Populations and Evolution · Quantitative Biology 2007-05-23 David Steinsaltz , Steven N. Evans , Kenneth W. Wachter

We investigate a multi-locus evolutionary model which is based on the DNA shuffling protocol widely applied in \textit{in vitro} directed evolution. This model incorporates selection, recombination and point mutations. The simplicity of the…

Biological Physics · Physics 2009-11-10 Weiqun Peng , Herbert Levine , Terence Hwa , David A. Kessler

We prove the existence of a global solution to the Cauchy problem for a nonlinear reaction-diffusion system coupled with a system of ordinary differential equations. The system models the propagation of a combustion front in a porous medium…

Analysis of PDEs · Mathematics 2016-04-19 J. C. da Mota , M. M. Santos , R. A. Santos

We discuss the population dynamics with selection and random diffusion, keeping the total population constant, in a fitness landscape associated with Constraint Satisfaction, a paradigm for difficult optimization problems. We obtain a phase…

Populations and Evolution · Quantitative Biology 2016-11-23 Tommaso Brotto , Guy Bunin , Jorge Kurchan

A class of parabolic cross-diffusion systems modeling the interaction of an arbitrary number of population species is analyzed in a bounded domain with no-flux boundary conditions. The equations are formally derived from a random-walk…

Analysis of PDEs · Mathematics 2015-02-20 Nicola Zamponi , Ansgar Jüngel

We study the asymptotic behavior of solutions of the Cauchy problem associated to a quantitative genetics model with a sexual mode of reproduction. It combines trait-dependent mortality and a nonlinear integral reproduction operator "the…

Analysis of PDEs · Mathematics 2023-08-30 Florian Patout

Mathematical theory of selection is developed within the frameworks of general models of inhomogeneous populations with continuous time. Methods that allow us to study the distribution dynamics under natural selection and to construct…

Populations and Evolution · Quantitative Biology 2009-12-22 Georgy P. Karev

Model selection for regression problems with an increasing number of covariates continues to be an important problem both theoretically and in applications. Model selection consistency and mean structure reconstruction depend on the…

Statistics Theory · Mathematics 2019-05-16 Zikun Yang , Andrew Womack

In this work, a mode of convergence for measurable functions is introduced. A related notion of Cauchy sequence is given and it is proved that this notion of convergence is complete in the sense that Cauchy sequences converge. Moreover, the…

Classical Analysis and ODEs · Mathematics 2024-04-17 Nuno J. Alves , João Paulos

This Letter studies the quasispecies dynamics of a population capable of genetic repair evolving on a time-dependent fitness landscape. We develop a model that considers an asexual population of single-stranded, conservatively replicating…

Populations and Evolution · Quantitative Biology 2009-11-13 Pavel Gorodetsky , Emmanuel Tannenbaum

Understanding posterior contraction behavior in Bayesian hierarchical models is of fundamental importance, but progress in this question is relatively sparse in comparison to the theory of density estimation. In this paper, we study two…

Statistics Theory · Mathematics 2025-12-22 Dat Do , Sunrit Chakraborty , Jonathan Terhorst , XuanLong Nguyen

Diffusion models are generative models that have recently demonstrated impressive performances in terms of sampling quality and density estimation in high dimensions. They rely on a forward continuous diffusion process and a backward…

Machine Learning · Computer Science 2024-02-07 Christian Horvat , Jean-Pascal Pfister