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SMT-based program analysis and verification often involve reasoning about program features that have been specified using quantifiers; incorporating quantifiers into SMT-based reasoning is, however, known to be challenging. If quantifier…

Logic in Computer Science · Computer Science 2024-04-30 Rui Ge , Ronald Garcia , Alexander J. Summers

Assurance cases provide an organized and explicit argument for correctness. They can dramatically improve the certification of Scientific Computing Software (SCS). Assurance cases have already been effectively used for safety cases for real…

Software Engineering · Computer Science 2020-01-01 Spencer Smith , Mojdeh Sayari Nejad , Alan Wassyng

The paper presents an approach for building consistent and applicable clinical decision support systems (CDSSs) using a data-driven predictive model aimed at resolving the problem of low applicability and scalability of CDSSs in real-world…

Artificial Intelligence · Computer Science 2022-02-18 Sergey V. Kovalchuk , Georgy D. Kopanitsa , Ilia V. Derevitskii , Daria A. Savitskaya

Clinical decision-making is a dynamic, interactive, and cyclic process where doctors have to repeatedly decide on which clinical action to perform and consider newly uncovered information for diagnosis and treatment. Large Language Models…

Computation and Language · Computer Science 2026-03-03 David Bani-Harouni , Chantal Pellegrini , Ege Özsoy , Nassir Navab , Matthias Keicher

Automated Machine Learning-based systems' integration into a wide range of tasks has expanded as a result of their performance and speed. Although there are numerous advantages to employing ML-based systems, if they are not interpretable,…

Machine Learning · Computer Science 2022-12-08 Ioannis Mollas , Nick Bassiliades , Grigorios Tsoumakas

The rapid proliferation of large language models (LLMs) in healthcare creates an urgent need for scalable and psychometrically sound evaluation methods. Conventional static benchmarks are costly to administer repeatedly, vulnerable to data…

Computation and Language · Computer Science 2026-03-26 Tianpeng Zheng , Zhehan Jiang , Jiayi Liu , Shicong Feng

In this paper, we present a novel diagnostic framework that integrates Knowledge Graphs (KGs) and Large Language Models (LLMs) to support system diagnostics in high-reliability systems such as nuclear power plants. Traditional diagnostic…

Artificial Intelligence · Computer Science 2025-09-01 Saman Marandi , Yu-Shu Hu , Mohammad Modarres

\textbf{Background:} Regulatory frameworks for AI in healthcare, including the EU AI Act and FDA guidance on AI/ML-based medical devices, require clinical decision support to demonstrate not only accuracy but auditability. Existing formal…

Artificial Intelligence · Computer Science 2026-04-24 Michael Bouzinier , Sergey Trifonov , Michael Chumack , Eugenia Lvova , Dmitry Etin

There is growing interest in using machine learning (ML) to support clinical diagnosis, but most approaches rely on static, fully observed datasets and fail to reflect the sequential, resource-aware reasoning clinicians use in practice.…

Artificial Intelligence · Computer Science 2025-11-18 Silas Ruhrberg Estévez , Nicolás Astorga , Mihaela van der Schaar

Evaluating large language models (LLMs) has recently emerged as a critical issue for safe and trustworthy application of LLMs in the medical domain. Although a variety of static medical question-answering (QA) benchmarks have been proposed,…

Computation and Language · Computer Science 2025-12-12 Gyutaek Oh , Sangjoon Park , Byung-Hoon Kim

We present iSMC, the first self-certifying model checker with interactive certification, a certification paradigm based on the theory of interactive proof systems. iSMC is a symbolic BDD-based model checker for arbitrary properties of…

Logic in Computer Science · Computer Science 2026-05-06 Philipp Czerner , Javier Esparza , Konrad Winslow

Knowledge editing (KE) provides a scalable approach for updating factual knowledge in large language models without full retraining. While previous studies have demonstrated effectiveness in general domains and medical QA tasks, little…

Artificial Intelligence · Computer Science 2025-08-12 Shengtao Wen , Haodong Chen , Yadong Wang , Zhongying Pan , Xiang Chen , Yu Tian , Bo Qian , Dong Liang , Sheng-Jun Huang

Clinical decision support tools (DST) promise improved healthcare outcomes by offering data-driven insights. While effective in lab settings, almost all DSTs have failed in practice. Empirical research diagnosed poor contextual fit as the…

Human-Computer Interaction · Computer Science 2019-04-23 Qian Yang , Aaron Steinfeld , John Zimmerman

There are several issues with the existing general machine translation or natural language generation evaluation metrics, and question-answering (QA) systems are indifferent in that context. To build robust QA systems, we need the ability…

Computation and Language · Computer Science 2022-07-06 Farida Mustafazade , Peter F. Ebbinghaus

Autonomous Driving Systems (ADS) use complex decision-making (DM) models with multimodal sensory inputs, making rigorous validation and verification (V&V) essential for safety and reliability. These models pose challenges in diagnosing…

Software Engineering · Computer Science 2025-10-07 Halit Eris , Stefan Wagner

Vehicle models have a long history of research and as of today are able to model the involved physics in a reasonable manner. However, each new vehicle has its new characteristics or parameters. The identification of these is the main task…

Computational Engineering, Finance, and Science · Computer Science 2024-12-11 Nicola Henkelmann , Stephan Rhode , Johannes von Keler

Data-driven Clinical Decision Support Systems (CDSS) have the potential to improve and standardise care with personalised probabilistic guidance. However, the size of data required necessitates collaborative learning from analogous CDSS's,…

Machine Learning · Computer Science 2022-11-15 Cécile Trottet , Thijs Vogels , Martin Jaggi , Mary-Anne Hartley

As learned control policies become increasingly common in autonomous systems, there is increasing need to ensure that they are interpretable and can be checked by human stakeholders. Formal specifications have been proposed as ways to…

Human-Computer Interaction · Computer Science 2024-07-04 Isabelle Hurley , Rohan Paleja , Ashley Suh , Jaime D. Peña , Ho Chit Siu

Schema matching (SM) and entity matching (EM) tasks are crucial for data integration. While large language models (LLMs) have shown promising results in these tasks, they suffer from hallucinations and confusion about task instructions.…

Computation and Language · Computer Science 2025-02-18 Yongqin Xu , Huan Li , Ke Chen , Lidan Shou

This paper contributes with a pragmatic evaluation framework for explainable Machine Learning (ML) models for clinical decision support. The study revealed a more nuanced role for ML explanation models, when these are pragmatically embedded…

Artificial Intelligence · Computer Science 2022-12-22 Oskar Wysocki , Jessica Katharine Davies , Markel Vigo , Anne Caroline Armstrong , Dónal Landers , Rebecca Lee , André Freitas