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Magnetic particle imaging (MPI) is an imaging modality exploiting the nonlinear magnetization behavior of (super-)paramagnetic nanoparticles to obtain a space- and often also time-dependent concentration of a tracer consisting of these…

Image and Video Processing · Electrical Eng. & Systems 2020-07-06 Sören Dittmer , Tobias Kluth , Mads Thorstein Roar Henriksen , Peter Maass

Purpose: Recent studies have shown that spin-lock MRI can simplify quantitative magnetization transfer (MT) by eliminating its dependency on water pool parameters, removing the need for a T1 map in macromolecular proton fraction (MPF)…

Model-based reconstruction approaches for the medical imaging modality Magnetic Particle Imaging (MPI) are typically based on the Langevin model, which assumes instantaneous alignment of the particles magnetic momenta with the applied…

Numerical Analysis · Mathematics 2026-03-13 Vladyslav Gapyak , Thomas März , Andreas Weinmann

We derive a new 3D model for magnetic particle imaging (MPI) that is able to incorporate realistic magnetic fields in the reconstruction process. In real MPI scanners, the generated magnetic fields have distortions that lead to deformed…

Numerical Analysis · Mathematics 2020-12-30 Gaël Bringout , Wolfgang Erb , Jürgen Frikel

Magnetic Particle Imaging (MPI) is a highly sensitive imaging method that enables the visualization of magnetic tracer materials with a temporal resolution of more than 46 volumes per second. In MPI the size of the field of view scales with…

Magnetic particle imaging (MPI) is an in vivo method to detect magnetic nanoparticles for cell tracking, vascular imaging, and molecular target imaging without ionizing radiation. Current magnetic particle imaging is accomplished by forming…

Magnetic Particle Imaging (MPI) is a recent imaging modality where superparamagnetic nanoparticles are employed as tracers. The reconstruction task is to obtain the spatial particle distribution from a voltage signal induced by the…

Numerical Analysis · Mathematics 2025-08-11 Thomas März , Vladyslav Gapyak , Andreas Weinmann

Magnetic Particle Imaging is an emerging imaging modality through which it is possible to detect tracers containing superparamagnetic nanoparticles. The exposure of the particles to dynamic magnetic fields generates a non-linear response…

Numerical Analysis · Mathematics 2024-06-19 Vladyslav Gapyak , Thomas März , Andreas Weinmann

We report on our progress in the development of an atomic magnetometer (AM) based low-frequency magnetic particle imaging (MPI) scanner, expected to be free from Specific Absorption Rate (SAR) and Peripheral Nerve Stimulation (PNS)…

Instrumentation and Detectors · Physics 2017-01-16 Simone Colombo , Victor Lebedev , Alexey Tonyushkin , Zoran D. Grujic , Vladimir Dolgovskiy , Antoine Weis

Magnetic particle spectroscopy (MPS) is one of the most versatile methods to characterize the magnetic properties of magnetic nanoparticles (MNPs). The excitation magnetic field is one of the most crucial factors that affects the MPS signal…

Applied Physics · Physics 2023-04-25 Shaoqi Sun , Shijie Sun , Lijun Xu , Jing Zhong

In semiconductor manufacturing, defect detection and localization are critical to ensuring product quality and yield. While X-ray imaging is a reliable non-destructive testing method, it is memory-intensive and time-consuming for…

Computer Vision and Pattern Recognition · Computer Science 2025-08-29 Aye Phyu Phyu Aung , Lucas Lum , Zhansen Shi , Wen Qiu , Bernice Zee , JM Chin , Yeow Kheng Lim , J. Senthilnath

We propose Microscopic Propagator Imaging (MPI) as a novel method to retrieve the indices of the microscopic propagator which is the probability density function of water displacements due to diffusion within the nervous tissue…

Neurons and Cognition · Quantitative Biology 2025-03-03 Tommaso Zajac , Gloria Menegaz , Marco Pizzolato

The image formation mechanism in Piezoresponse Force Microscopy (PFM) of capacitor structures is analyzed. We demonstrate that the spatial resolution is a bilinear function of film and top electrode thicknesses, and derive the corresponding…

Background and Purpose: A current algorithm to obtain a synthetic myelin volume fraction map (SyMVF) from rapid simultaneous relaxometry imaging (RSRI) has a potential problem, that it does not incorporate information from surrounding…

The image reconstruction problem of the tomographic imaging technique magnetic particle imaging (MPI) requires the solution of a linear inverse problem. One prerequisite for this task is that the imaging operator that describes the mapping…

Computational Physics · Physics 2019-07-12 Tobias Kluth , Patryk Szwargulski , Tobias Knopp

We propose a novel two-phase approach to functional network estimation of multi-subject functional Magnetic Resonance Imaging (fMRI) data, which applies model-based image segmentation to determine a group-representative connectivity map. In…

Computation · Statistics 2018-09-05 Aditi Iyer , Bingjing Tang , Vinayak Rao , Nan Kong

Magnetic particle spectroscopy (MPS), also called magnetization response spectroscopy, is a novel measurement tool derived from magnetic particle imaging (MPI). It can be interpreted as a zero-dimensional version of MPI scanner. MPS was…

Applied Physics · Physics 2020-03-24 Kai Wu , Diqing Su , Renata Saha , Jinming Liu , Vinit Kumar Chugh , Jian-Ping Wang

Present protocols for obtaining the ultimate magnetic sensitivity of optically pumped magnetometers (OPMs) utilizing alkali-metal ensembles rely on uncorrelated atoms in stretched states. A new approach for calculating the spin projection…

Quantum Physics · Physics 2024-02-23 K. Mouloudakis , V. Koutrouli , I. K. Kominis , M. W. Mitchell , G. Vasilakis

Magnetic Particle Imaging (MPI) is a novel medical imaging modality. One of the established methods for MPI reconstruction is based on the System Matrix (SM). However, the calibration of the SM is often time-consuming and requires repeated…

Computer Vision and Pattern Recognition · Computer Science 2025-11-11 Xuqing Geng , Lei Su , Zhongwei Bian , Zewen Sun , Jiaxuan Wen , Jie Tian , Yang Du

Magnetic Particle Imaging (MPI) has been successfully used to visualize the distribution of superparamagnetic nanoparticles within 3D volumes with high sensitivity in real time. Since the magnetic field topology of MPI scanners is well…