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The mortality rate of many complex multicellular organisms increase with age, which suggests that net aging damage is accumulative, despite remodeling processes. But how exactly do little mishaps in the cellular level accumulate and spread…

Tissues and Organs · Quantitative Biology 2017-12-12 Daniel Suma , Aylin Acun , Pinar Zorlutuna , Dervis Can Vural

The results of modeling of radiation defects formation and evolution on the surface and in the volume of a crystal are presented in this article. Statistical properties are calculated for the investigated system. It is revealed that defects…

Adaptation and Self-Organizing Systems · Physics 2007-05-23 K. S. Baktybekov , S. G. Karstina , E. N. Vertyagina

Rod-like bacteria maintain their cylindrical shapes with remarkable precision during growth. However, they are also capable to adapt their shapes to external forces and constraints, for example by growing into narrow or curved confinements.…

Subcellular Processes · Quantitative Biology 2016-02-10 Ariel Amir , Sven van Teeffelen

The equations of a planar elastica under pressure can be rewritten in a useful form by parametrising the variables in terms of the local orientation angle, $\theta$, instead of the arc length. This ``$\theta$-formulation'' lends itself to a…

Soft Condensed Matter · Physics 2023-07-25 Gregory Kozyreff , Emmanuel Siéfert , Basile Radisson , Fabian Brau

Collective cell motions underlie structure formation during embryonic development. Tissues exhibit emergent multicellular characteristics such as jamming, rigidity transitions, and glassy dynamics, but there remain questions about how those…

Biological Physics · Physics 2023-12-13 Evan Thomas , Sevan Hopyan

Foa a given local ring, we study the fiber cone of ideals with analytic spread one. In this case, the fiber cone has a strucure as a module over its Noether normalization which is a polynomial ring in one variable over the residue field.…

Commutative Algebra · Mathematics 2007-05-23 Teresa Cortadellas , Santiago Zarzuela

New invariants for 2-dimensional cell complexes are defined, which can be interpreted as curvature bounds. These invariants are proved to be rational and computable in a companion article. This document is a survey that collects theorems…

Group Theory · Mathematics 2024-05-16 Henry Wilton

Starting from the hypothesis that both physics, in particular space-time and the physical vacuum, and the corresponding mathematics are discrete on the Planck scale we develop a certain framework in form of a class of ' cellular networks'…

High Energy Physics - Theory · Physics 2016-09-06 Manfred Requardt

A growing or shrinking disc will adopt a conical shape, its intrinsic geometry characterized by a surplus angle $se$ at the apex. If growth is slow, the cone will find its equilibrium. Whereas this is trivial if $se <= 0$, the disc can fold…

Other Condensed Matter · Physics 2008-10-14 Martin Michael Mueller , Martine Ben Amar , Jemal Guven

We report here new electrical laws, derived from nonlinear electro-diffusion theory, about the effect of the local geometrical structure, such as curvature, on the electrical properties of a cell. We adopt the Poisson-Nernst-Planck (PNP)…

Subcellular Processes · Quantitative Biology 2017-11-22 Jerome Cartailler , Zeev Schuss , David Holcman

Development combines three basic processes asymmetric --- cell division, signaling and gene regulation --- in a multitude of ways to create an overwhelming diversity of multicellular life-forms. Here, we attempt to chart this diversity…

Molecular Networks · Quantitative Biology 2020-01-01 Somya Mani , Tsvi Tlusty

Ordered polarity alignment of a cell population plays a vital role in biology, such as in hair follicle alignment and asymmetric cell division. Here, we propose a theoretical framework for the understanding of generic dynamical properties…

Pattern Formation and Solitons · Physics 2016-12-13 Kaori Sugimura , Hiroshi Kori

Consider a lipid membrane with a free exposed edge. The energy describing this membrane is quadratic in the extrinsic curvature of its geometry; that describing the edge is proportional to its length. In this note we determine the boundary…

Soft Condensed Matter · Physics 2009-11-07 R. Capovilla , J. Guven , J. A. Santiago

A stationary Poisson line tessellation is considered whose directional distribution is concentrated on two different atoms with some positive weights. The shape of the typical cell of such a tessellation is studied when its area or its…

Probability · Mathematics 2014-07-08 Mareen Beermann , Claudia Redenbach , Christoph Thaele

Connecting cell behavior to tissue shape and mechanics is a key challenge in the physics of morphogenesis. Cytoskeletal turnover precludes a fixed reference state, and tensions are actively generated independently of strain; so conventional…

Soft Condensed Matter · Physics 2026-05-28 Nikolas H. Claussen , Fridtjof Brauns , Boris I. Shraiman

The distribution of the deformations of elementary cells is studied in an abstract lattice constructed from the existence of the empty set. One combination rule determining oriented sequences with continuity of set-distance function in such…

General Physics · Physics 2007-05-23 Michel Bounias , Volodymyr Krasnoholovets

A model describing cell membranes as optimal shapes with regard to the $L^2$-deficit of their mean curvature to a given constant called spontaneous curvature is considered. It is shown that the corresponding energy functional is lower…

Differential Geometry · Mathematics 2023-11-01 Christian Scharrer

Cell extrusion is an essential mechanism for controlling cell density in epithelial tissues. Another essential element of epithelia is curvature, which is required to achieve complex shapes, like in the lung or intestine. Here we introduce…

Nearly all cell models explicitly or implicitly deal with the biophysical constraints that must be respected for life to persist. Despite this, there is almost no systematicity in how these constraints are implemented, and we lack a…

Cell Behavior · Quantitative Biology 2026-05-20 Connor McShaffrey , Eran Agmon , Randall D. Beer

We propose a model of the functional architecture of curvature sensible cells in the visual cortex that associates curvature with scale. The feature space of orientation and position is naturally enhanced via its oriented prolongation,…

Neurons and Cognition · Quantitative Biology 2025-04-24 Vasiliki Liontou