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Is it possible to estimate the dependence of a growing and dividing population on a given trait in the case where this trait is not directly accessible by experimental measurements, but making use of measurements of another variable? This…

Statistics Theory · Mathematics 2019-07-12 Marie Doumic , Adélaïde Olivier , Lydia Robert

We show that one can construct two equivalent gauge theories from a linking theory and give a general construction principle for linking theories which we use to construct a linking theory that proves the equivalence of General Relativity…

General Relativity and Quantum Cosmology · Physics 2015-05-27 Henrique Gomes , Tim Koslowski

This thesis deals with shape optimization for contact mechanics. More specifically, the linear elasticity model is considered under the small deformations hypothesis, and the elastic body is assumed to be in contact (sliding or with Tresca…

Optimization and Control · Mathematics 2022-08-30 Bastien Chaudet-Dumas

Protrusions at the leading-edge of a cell play an important role in sensing the extracellular cues, during cellular spreading and motility. Recent studies provided indications that these protrusions wrap (coil) around the extra-cellular…

We derive a fully covariant theory of the mechanics of active surfaces. This theory provides a framework for the study of active biological or chemical processes at surfaces, such as the cell cortex, the mechanics of epithelial tissues, or…

Biological Physics · Physics 2017-09-13 Guillaume Salbreux , Frank Jülicher

The migration of cells is relevant for processes such as morphogenesis, wound healing, and invasion of cancer cells. In order to move, single cells deform cyclically. However, it is not understood how these shape oscillations influence…

Biological Physics · Physics 2019-09-04 Matteo Campo , Simon K. Schnyder , John J. Molina , Thomas Speck , Ryoichi Yamamoto

Adhesive cell-substrate interactions are crucial for cell motility and are responsible for the necessary traction that propels cells. These interactions can also change the shape of the cell, analogous to liquid droplet wetting on adhesive…

Shape is one of the important characteristics for the structures observed in living organisms. Whereas biologists have proposed models where the shape is controlled on a molecular level [1], physicists, following Turing [2] and d'Arcy…

Tissues and Organs · Quantitative Biology 2010-10-11 Etienne Couturier , Sylvain Courrech du Pont , Stephane Douady

This paper develops a uniformly valid and asymptotically nonconservative test based on projection for a class of shape restrictions. The key insight we exploit is that these restrictions form convex cones, a simple and yet elegant structure…

Econometrics · Economics 2021-09-21 Zheng Fang , Juwon Seo

Many eukaryotic cells use the active waving motion of flexible flagella to self-propel in viscous fluids. However, the criteria governing the selection of particular flagellar waveforms among all possible shapes has proved elusive so far.…

Biological Physics · Physics 2013-08-02 Christophe Eloy , Eric Lauga

Let us consider the simplest model of one-dimensional probabilistic cellular automata (PCA). The cells are indexed by the integers, the alphabet is {0, 1}, and all the cells evolve synchronously. The new content of a cell is randomly…

Probability · Mathematics 2012-07-26 Jean Mairesse , Irene Marcovici

Curvature in biological membranes can be generated by a variety of different molecular mechanisms such as protein scaffolding, lipid or protein asymmetry, cytoskeletal forces, etc. These mechanisms have the net effect of generating stresses…

We consider a one-dimensional discrete-space birth process with a bounded number of particle per site. Under the assumptions of the finite range of interaction, translation invariance, and non-degeneracy, we prove a shape theorem. We also…

Probability · Mathematics 2022-02-23 Viktor Bezborodov , Luca Di Persio , Tyll Krueger

In this article, we propose a general framework to study the dynamics and topology of cellular networks that capture the geometry of cell packings in two-dimensional tissues. Such epithelia undergo large-scale deformation during…

Tissues and Organs · Quantitative Biology 2017-09-08 Matthias Merkel , Raphaël Etournay , Marko Popović , Guillaume Salbreux , Suzanne Eaton , Frank Jülicher

The formula for analytic torsion of a cone in even dimensions is comprised of three terms. The first two terms are well understood and given by an algebraic combination of the Betti numbers and the analytic torsion of the cone base. The…

Spectral Theory · Mathematics 2015-02-02 Boris Vertman

To each del Pezzo surface (resp. ruled surface, ruled surface with a section), we describe a natural Lie algebra bundle of type E_n (resp. D_n, A_n) over it. Using lines and rulings on any such surface, we describe various representation…

Algebraic Geometry · Mathematics 2007-05-23 Naichung Conan Leung

Gradual disruption of the actin cytoskeleton induces a series of structural shape changes in cells leading to a transformation of cylindrical cell extensions into a periodic chain of "pearls". Quantitative measurements of the pearling…

Biological Physics · Physics 2010-08-06 Roy Bar-Ziv , Tsvi Tlusty , Elisha Moses , Samuel A. Safran , Alexander Bershadsky

Programming the non-uniform growth of a responsive polymer gel has emerged as a powerful tool to shape sheets into prescribed three dimensional shapes. We demonstrate that shapes with zero Gaussian curvature, except at singularities,…

Soft Condensed Matter · Physics 2014-10-29 N. P. Bende , R. C. Hayward , C. D. Santangelo

The vertex model of epithelia describes the apical surface of a tissue as a tiling of polygonal cells, with a mechanical energy governed by deviations in cell shape from preferred, or target, area, $A_0$, and perimeter, $P_0$. The model…

Soft Condensed Matter · Physics 2023-04-12 Michael F. Staddon , Arthur Hernandez , Mark J. Bowick , Michael Moshe , M. Cristina Marchetti

The study of organoids, artificially grown cell aggregates with the functionality and small-scale anatomy of real organs, is one of the most active areas of research in biology and biophysics, yet the basic physical origins of their…

Biological Physics · Physics 2021-10-12 Jan Rozman , Matej Krajnc , Primož Ziherl
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