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The global attractor conjecture says that toric dynamical systems (i.e., a class of polynomial dynamical systems on the positive orthant) have a globally attracting point within each positive linear invariant subspace -- or, equivalently,…

Dynamical Systems · Mathematics 2016-01-12 Gheorghe Craciun

An important dynamical property of biological interaction networks is persistence, which intuitively means that "no species goes extinct". It has been conjectured that dynamical system models of weakly reversible networks (i.e., networks…

Dynamical Systems · Mathematics 2019-06-21 Gheorghe Craciun , Abhishek Deshpande

Dynamical systems with polynomial right-hand sides are very important in various applications, e.g., in biochemistry and population dynamics. The mathematical study of these dynamical systems is challenging due to the possibility of…

Dynamical Systems · Mathematics 2026-01-16 Balázs Boros , Gheorghe Craciun , Oskar Henriksson , Jiaxin Jin , Diego Rojas La Luz

Systems of differential equations with polynomial right-hand sides are very common in applications. In particular, when restricted to the positive orthant, they appear naturally (according to the law of mass-action kinetics) in ecology,…

Dynamical Systems · Mathematics 2023-03-06 Gheorghe Craciun , Abhishek Deshpande , Jiaxin Jin

Polynomial dynamical systems (i.e. dynamical systems with polynomial right hand side) are ubiquitous in applications, especially as models of reaction networks and interaction networks. The properties of general polynomial dynamical systems…

Dynamical Systems · Mathematics 2023-05-31 Gheorghe Craciun , Abhishek Deshpande , Jiaxin Jin

Polynomial dynamical systems are widely used to model and study real phenomena. In biochemistry, they are the preferred choice for modelling the concentration of chemical species in reaction networks with mass-action kinetics. These systems…

Algebraic Geometry · Mathematics 2014-12-30 Elisenda Feliu

This paper is concerned with the dynamical properties of deterministically modeled chemical reaction systems. Specifically, this paper provides a proof of the Global Attractor Conjecture in the setting where the underlying reaction diagram…

Dynamical Systems · Mathematics 2011-05-18 David F. Anderson

We study families of polynomial dynamical systems inspired by biochemical reaction networks. We focus on complex balanced mass-action systems, which have also been called toric. They are known or conjectured to enjoy very strong dynamical…

Algebraic Geometry · Mathematics 2022-02-02 Laura Brustenga i Moncusí , Gheorghe Craciun , Miruna-Stefana Sorea

Toric differential inclusions play a pivotal role in providing a rigorous interpretation of the connection between weak reversibility and the persistence of mass-action systems and polynomial dynamical systems. We introduce the notion of…

Dynamical Systems · Mathematics 2019-10-15 Gheorghe Craciun , Abhishek Deshpande , Hyejin Jenny Yeon

This paper introduces the class of "strongly endotactic networks", a subclass of the endotactic networks introduced by G. Craciun, F. Nazarov, and C. Pantea. The main result states that the global attractor conjecture holds for…

Dynamical Systems · Mathematics 2014-10-07 Manoj Gopalkrishnan , Ezra Miller , Anne Shiu

The induced kinetic differential equation of a reaction network endowed with mass action type kinetics is a system of polynomial differential equations. The problem studied here is: Given a polynomial differential equation, is it possible…

Dynamical Systems · Mathematics 2019-09-10 G. Craciun , M. D. Johnston , G. Szederkényi , E. Tonello , J. Tóth , P. Y. Yu

Dot product embeddings take a graph and construct vectors for nodes such that dot products between two vectors give the strength of the edge. Dot products make a strong transitivity assumption, however, many important forces generating…

Social and Information Networks · Computer Science 2023-03-24 Alexander Peysakhovich , Anna Klimovskaia Susmel , Leon Bottou

The analysis of observable phenomena (for instance, in biology or physics) allows the detection of dynamical behaviors and, conversely, starting from a desired behavior allows the design of objects exhibiting that behavior in engineering.…

Discrete Mathematics · Computer Science 2026-04-10 Antonio E. Porreca , Marius Rolland

Mathematical models of reaction networks can exhibit very complex dynamics, including multistability, oscillations, and chaotic dynamics. On the other hand, under some additional assumptions on the network or on parameter values, these…

Dynamical Systems · Mathematics 2025-03-14 Gheorghe Craciun , Abhishek Deshpande , Jiaxin Jin

In the study of reaction networks and the polynomial dynamical systems that they generate, special classes of networks with important properties have been identified. These include reversible, weakly reversible}, and, more recently,…

Dynamical Systems · Mathematics 2020-07-30 David F. Anderson , James D. Brunner , Gheorghe Craciun , Matthew D. Johnston

This paper shows that the celebrated Embedding Theorem of Takens is a particular case of a much more general statement according to which, randomly generated linear state-space representations of generic observations of an invertible…

Dynamical Systems · Mathematics 2023-08-09 Lyudmila Grigoryeva , Allen Hart , Juan-Pablo Ortega

A persistent dynamical system in $\mathbb{R}^d_{> 0}$ is one whose solutions have positive lower bounds for large $t$, while a permanent dynamical system in $\mathbb{R}^d_{> 0}$ is one whose solutions have uniform upper and lower bounds for…

Dynamical Systems · Mathematics 2019-10-29 James D. Brunner , Gheorghe Craciun

Toric dynamical systems are known as complex balancing mass action systems in the mathematical chemistry literature, where many of their remarkable properties have been established. They include as special cases all deficiency zero systems…

Dynamical Systems · Mathematics 2007-11-03 Gheorghe Craciun , Alicia Dickenstein , Anne Shiu , Bernd Sturmfels

Differential equations are a ubiquitous tool to study dynamics, ranging from physical systems to complex systems, where a large number of agents interact through a graph with non-trivial topological features. Data-driven approximations of…

Statistical Mechanics · Physics 2024-04-26 Vaiva Vasiliauskaite , Nino Antulov-Fantulin

A fundamental theory is presented for the mechanical response of polymer networks undergoing large deformation which seamlessly integrates statistical mechanical principles with macroscopic thermodynamic constitutive theory. Our formulation…

Soft Condensed Matter · Physics 2020-07-06 Michael R. Buche , Meredith N. Silberstein
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