English
Related papers

Related papers: The Thermodynamic Uncertainty Relation in Biochemi…

200 papers

The thermodynamic uncertainty relation expresses a universal trade-off between precision and entropy production, which applies in its original formulation to current observables in steady-state systems. We generalize this relation to…

Statistical Mechanics · Physics 2018-12-06 Timur Koyuk , Udo Seifert , Patrick Pietzonka

Maintained by environmental fluxes, biological systems are thermodynamic processes that operate far from equilibrium without detailed-balance dynamics. Yet, they often exhibit well defined nonequilibrium steady states (NESSs). More…

Statistical Mechanics · Physics 2017-08-02 P. M. Riechers , J. P. Crutchfield

Circadian clocks ubiquitous in life forms ranging bacteria to multi-cellular organisms, often exhibit intrinsic temperature compensation; the period of circadian oscillators is maintained constant over a range of physiological temperatures,…

Molecular Networks · Quantitative Biology 2014-07-21 Tetsuhiro S. Hatakeyama , Kunihiko Kaneko

The network of biochemical reactions inside living organisms is characterized by an overwhelming complexity which stems from the sheer number of reactions and from the complicated topology of biochemical cycles. However the high speed of…

Biological Physics · Physics 2009-10-30 Edoardo Milotti , Alessio Del Fabbro , Roberto Chignola

Molecular circadian clocks, that are found in all nucleated cells of mammals, are known to dictate rhythms of approximately 24 hours (circa diem) to many physiological processes. This includes metabolism (e.g., temperature, hormonal blood…

Analysis of PDEs · Mathematics 2011-03-14 Jean Clairambault , Stephane Gaubert , Thomas Lepoutre

The discerning behavior of living systems relies on accurate interactions selected from the lot of molecular collisions occurring in the cell. To ensure the reliability of interactions, binding partners are classically envisioned as finely…

Molecular Networks · Quantitative Biology 2016-09-28 Denis Michel , Benjamin Boutin , Philippe Ruelle

Biochemical circadian rhythm oscillations play an important role in many signalling mechanisms. In this work, we explore some of the biophysical mechanisms responsible for sustaining robust oscillations by constructing a minimal but…

Biological Physics · Physics 2021-07-16 Agnish Kumar Behera , Clara del Junco , Suriyanarayanan Vaikuntanathan

Investigation of states with a periodic time dependence of physical quantities attracts a considerable interest now. Although it has been proposed initially that such states (coined Quantum Time Crystals) might be macroscopic and…

Strongly Correlated Electrons · Physics 2019-11-07 Konstantin B. Efetov

All previously derived thermodynamic fluctuation theorems (FTs) that concern multiple co-evolving systems have required that each system can only change its state during an associated pre-fixed, limited set of time intervals. However, in…

Statistical Mechanics · Physics 2021-04-16 David H. Wolpert

The gene networks that comprise the circadian clock modulate biological function across a range of scales, from gene expression to performance and adaptive behaviour. The clock functions by generating endogenous rhythms that can be…

Molecular Networks · Quantitative Biology 2012-10-25 Ozgur Akman , Steven Watterson , Andrew Parton , Nigel Binns , Andrew Millar , Peter Ghazal

Fluctuation theorems are fundamental extensions of the second law of thermodynamics for small nonequilibrium systems. While work and heat are equally important forms of energy exchange, fluctuation relations have not been experimentally…

Statistical Mechanics · Physics 2022-02-24 Markus Rademacher , Michael Konopik , Maxime Debiossac , David Grass , Eric Lutz , Nikolai Kiesel

We introduce a new technique to bound the fluctuations exhibited by a physical system, based on the Euclidean geometry of the space of observables. Through a simple unifying argument, we derive a sweeping generalization of so-called…

Statistical Mechanics · Physics 2020-06-24 Gianmaria Falasco , Massimiliano Esposito , Jean-Charles Delvenne

The thermodynamic uncertainty relation is an inequality stating that it is impossible to attain higher precision than the bound defined by entropy production. In statistical inference theory, information inequalities assert that it is…

Statistical Mechanics · Physics 2019-06-26 Yoshihiko Hasegawa , Tan Van Vu

Simulations are performed of a small quantum system interacting with a quantum environment. The system consists of various initial states of two harmonic oscillators coupled to give normal modes. The environment is "designed" by its level…

Statistical Mechanics · Physics 2015-06-15 George L. Barnes , Michael E. Kellman

Circadian clocks are biochemical oscillators that allow organisms to estimate the time of the day. These oscillators are inherently noisy due to the discrete nature of the reactants and the stochastic character of their interactions. To…

Biological Physics · Physics 2018-03-21 Michele Monti , David K. Lubensky , Pieter Rein ten Wolde

Understanding different aspects of time is at the core of many areas in theoretical physics. Minimal models of continuous stochastic and quantum clocks have been proposed to explore fundamental limitations on the performance of timekeeping…

Quantum Physics · Physics 2026-03-31 Ludmila Viotti , Marcus Huber , Rosario Fazio , Gonzalo Manzano

A trade-off between the precision of an arbitrary current and the dissipation, known as the thermodynamic uncertainty relation, has been investigated for various Markovian systems. Here, we study the thermodynamic uncertainty relation for…

Statistical Mechanics · Physics 2019-09-23 Tan Van Vu , Yoshihiko Hasegawa

In the framework of the Lindblad theory for open quantum systems, we derive closed analytical expressions of the Heisenberg and Schr\"odinger generalized uncertainty functions for a particle moving in a harmonic oscillator potential. The…

Quantum Physics · Physics 2009-11-13 A. Isar , W. Scheid

Quantum thermodynamic uncertainty relations establish fundamental trade-offs between the precision achievable in quantum systems and associated thermodynamic quantities such as entropy production or dynamical activity. While foundational,…

Quantum Physics · Physics 2025-09-23 Nobumasa Ishida , Yoshihiko Hasegawa

Living systems maintain or increase local order by working against the Second Law of Thermodynamics. Thermodynamic consistency is restored as they dissipate heat, thereby increasing the net entropy of their environment. Recently introduced…

Biological Physics · Physics 2021-05-03 Dominic J. Skinner , Jörn Dunkel