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Related papers: The Thermodynamic Uncertainty Relation in Biochemi…

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We examine a biomolecular machine involving a driven, observable process coupled to a hidden process in a kinetically cooperative manner. A stochastic thermodynamics framework is employed to analyze a fluctuation theorem for the…

Statistical Mechanics · Physics 2025-11-14 D. Evan Piephoff , Jianshu Cao

Thermodynamic uncertainty principles make up one of the few rare anchors in the largely uncharted waters of nonequilibrium systems, the fluctuation theorems being the more familiar. In this work we aim to trace the uncertainties of…

Statistical Mechanics · Physics 2022-08-02 Hang Dong , Daniel Reiche , Jen-Tsung Hsiang , Bei-Lok Hu

In a finite system driven out of equilibrium by a constant external force the thermodynamic uncertainty relation (TUR) bounds the variance of the conjugate current variable by the thermodynamic cost of maintaining the non-equilibrium…

Statistical Mechanics · Physics 2021-08-17 David Hartich , Aljaz Godec

Uncertainty relations state that there exist certain incompatible measurements, to which the outcomes cannot be simultaneously predicted. While the exact incompatibility of quantum measurements dictated by such uncertainty relations can be…

Quantum Physics · Physics 2015-06-05 Esther Hänggi , Stephanie Wehner

We give a short review of known exact inequalities that can be interpreted as "energy-time" and "frequency-time" uncertainty relations. In particular we discuss a precise form of signals minimizing the physical frequency-time uncertainty…

Quantum Physics · Physics 2015-04-06 V. V. Dodonov , A. V. Dodonov

Relative fluctuations of observables in discrete stochastic systems are bounded at all times by the mean dynamical activity in the system, quantified by the mean number of jumps. This constitutes a kinetic uncertainty relation that is…

Statistical Mechanics · Physics 2019-01-08 Ivan Di Terlizzi , Marco Baiesi

We study the fluctuations of generic currents in multi-terminal, multi-channel quantum transport settings. In the quantum regime, these fluctuations and the resulting precision differ strongly depending on whether the device is of fermionic…

Mesoscale and Nanoscale Physics · Physics 2025-04-08 Didrik Palmqvist , Ludovico Tesser , Janine Splettstoesser

A model of coupled molecular oscillators is proposed to study nonequilibrium thermodynamics of synchronization. We find that synchronization of nonequilibrium oscillators costs energy even when the oscillator-oscillator coupling is…

Biological Physics · Physics 2020-01-29 Dongliang Zhang , Yuansheng Cao , Qi Ouyang , Yuhai Tu

We extend a class of recently derived thermodynamic uncertainty relations to vector-valued observables. In contrast to the scalar-valued observables examined previously, this multidimensional thermodynamic uncertainty relation provides a…

Statistical Mechanics · Physics 2019-10-22 Andreas Dechant

Circadian clocks exhibit the robustness of period and plasticity of phase against environmental changes such as temperature and nutrient conditions. Thus far, however, it is unclear how both are simultaneously achieved. By investigating…

Molecular Networks · Quantitative Biology 2015-12-08 Tetsuhiro S. Hatakeyama , Kunihiko Kaneko

We study fluctuations in diffusion-limited reaction systems driven out of their stationary state. Using a numerically exact method, we investigate fluctuation ratios in various systems which differ by their level of violation of microscopic…

Statistical Mechanics · Physics 2009-11-13 Sven Dorosz , Michel Pleimling

Biologically driven non-equilibrium fluctuations are often characterized by their non-Gaussianity or by an "effective temperature", which is frequency dependent and higher than the ambient temperature. We address these two measures…

Biological Physics · Physics 2011-06-16 Eyal Ben-Isaac , YongKeun Park , Gabriel Popescu , Frank L. H. Brown , Nir S. Gov , Yair Shokef

Small thermodynamic systems exhibit peculiar behavior different from that observed in long-scale systems. Non-equilibrium processes taking place in those systems are strongly influenced by the presence of fluctuations which can be large.…

Statistical Mechanics · Physics 2007-05-23 J. M. Rubi

The thermodynamic uncertainty relation, which establishes a universal trade-off between the relative fluctuation of arbitrary currents and the dissipation, has been found for various Markovian systems. However, this relation has not been…

Statistical Mechanics · Physics 2019-07-31 Tan Van Vu , Yoshihiko Hasegawa

Biological rhythms are generated by pacemaker organs, such as the heart pacemaker organ (the sinoatrial node) and the master clock of the circadian rhythms (the suprachiasmatic nucleus), which are composed of a network of autonomously…

Cell Behavior · Quantitative Biology 2016-08-23 Hiroshi Kori , Yoji Kawamura , Naoki Masuda

We study the fundamental limitations of implementing time-dependent Hamiltonian protocols when ''time'' is provided by a quantum clock rather than an external classical parameter. For a parametric harmonic oscillator controlled through a…

Quantum Physics · Physics 2026-03-13 Guillermo Perna , Federico Centrone , Esteban Calzetta

The development of systemic approaches in biology has put emphasis on identifying genetic modules whose behavior can be modeled accurately so as to gain insight into their structure and function. However most gene circuits in a cell are…

Molecular Networks · Quantitative Biology 2010-12-10 Quentin Thommen , Benjamin Pfeuty , Pierre-Emmanuel Morant , Florence Corellou , François-Yves Bouget , Marc Lefranc

It is essential that mesoscopic simulations of reactive systems reproduce the correct statistical distributions at thermodynamic equilibrium. By considering a compressible fluctuating hydrodynamics (FHD) simulation method of ideal gas…

Oscillatory chemical reactions often serve as a timing clock of cellular processes in living cells. The temporal dynamics of protein concentration levels is thus of great interest in biology. Here we propose a theoretical framework to…

Systems and Control · Computer Science 2015-03-20 Yutaka Hori , Shinji Hara

We derive a Thermodynamic Uncertainty Relation bounding the mean squared displacement of a Gaussian process with memory, driven out of equilibrium by unbalanced thermal baths and/or by external forces. Our bound is tighter with respect to…

Statistical Mechanics · Physics 2023-05-23 Andrea Plati , Andrea Puglisi , Alessandro Sarracino