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Breast Magnetic Resonance Imaging (MRI) demonstrates the highest sensitivity for breast cancer detection among imaging modalities and is standard practice for high-risk women. Interpreting the multi-sequence MRI is time-consuming and prone…

Computer Vision and Pattern Recognition · Computer Science 2025-04-08 Luyang Luo , Mingxiang Wu , Mei Li , Yi Xin , Qiong Wang , Varut Vardhanabhuti , Winnie CW Chu , Zhenhui Li , Juan Zhou , Pranav Rajpurkar , Hao Chen

Breast lesion localization using tactile imaging is a new and developing direction in medical science. To achieve the goal, proper image reconstruction and image registration can be a valuable asset. In this paper, a new approach of the…

Computer Vision and Pattern Recognition · Computer Science 2019-10-16 Shuvendu Rana , Rory Hampson , Gordon Dobie

Background: The vast computational resources that became available during the past decade enabled the development and simulation of increasingly complex mathematical models of cancer growth. These models typically involve many free…

Quantitative Methods · Quantitative Biology 2010-11-19 Diego Fernandez Slezak , Cecilia Suarez , Guillermo A. Cecchi , Guillermo Marshall , Gustavo Stolovitzky

Bimetric theory describes a massless and a massive spin-2 field with fully non-linear (self-)interactions. It has a rich phenomenology and has been successfully tested with several data sets. However, the observational constraints have not…

General Relativity and Quantum Cosmology · Physics 2020-10-20 Marvin Lüben , Angnis Schmidt-May , Jochen Weller

Reliable predictions from systems biology models require knowing whether parameters can be estimated from available data, and with what certainty. Identifiability analysis reveals whether parameters are learnable in principle (structural…

In this paper, we present a robotic model-based reinforcement learning method that combines ideas from model identification and model predictive control. We use a feature-based representation of the dynamics that allows the dynamics model…

Machine Learning · Computer Science 2016-03-16 Christopher Xie , Sachin Patil , Teodor Moldovan , Sergey Levine , Pieter Abbeel

In this paper we present recent results on parametric analysis of biological models. The underlying method is based on the algorithms for computing trajectory sets of hybrid systems with polynomial dynamics. The method is then applied to…

Computational Engineering, Finance, and Science · Computer Science 2012-08-21 Romain Testylier , Thao Dang

Dynamical modelling lies at the heart of our understanding of physical systems. Its role in science is deeper than mere operational forecasting, in that it allows us to evaluate the adequacy of the mathematical structure of our models.…

Data Analysis, Statistics and Probability · Physics 2015-06-05 Hailiang Du , Leonard A. Smith

In recent years, disease mapping studies have become a routine application within geographical epidemiology and are typically analysed within a Bayesian hierarchical model formulation. A variety of model formulations for the latent level…

Methodology · Statistics 2016-01-07 Andrea Riebler , Sigrunn H. Sørbye , Daniel Simpson , Håvard Rue

Morphogenesis is a tightly regulated process that has been studied for decades. We are developing data-based and image-basd mechanistic models for a range of developmental processes with a view to integrate the available knowledge and to…

Quantitative Methods · Quantitative Biology 2013-09-10 Denis Menshykau , Srivathsan Adivarahan , Philipp Germann , Lisa Lermuzeaux , Dagmar Iber

The problem of identifiability of model parameters for open quantum systems is considered by investigating two-level dephasing systems. We discuss under which conditions full information about the Hamiltonian and dephasing parameters can be…

Quantum Physics · Physics 2015-01-15 Er-ling Gong , Weiwei Zhou , S. G. Schirmer , Zhi-Qiang Sun , Ming Zhang

We introduce the Optimal Fingerprinting Process which is aimed at accurately identifying the parameters which characterize the dynamics of a physical system. A database is first built from the time evolution of an ensemble of dynamical…

Quantum Physics · Physics 2017-12-06 Q. Ansel , M. Tesch , S. J. Glaser , D. Sugny

The inherent complexity of biological systems gives rise to complicated mechanistic models with a large number of parameters. On the other hand, the collective behavior of these systems can often be characterized by a relatively small…

Quantitative Methods · Quantitative Biology 2016-06-15 Mark K. Transtrum , Peng Qiu

This paper presents an algorithm to geometrically characterize inertial parameter identifiability for an articulated robot. The geometric approach tests identifiability across the infinite space of configurations using only a finite set of…

Robotics · Computer Science 2023-09-21 Patrick M. Wensing , Günter Niemeyer , Jean-Jacques E. Slotine

This paper presents a reproducible and physically feasible dynamic parameter identification framework for CRANE-X7, a low-cost robot arm driven by modular smart actuators. To improve practical identifiability, products of inertia are…

Robotics · Computer Science 2026-05-18 Junji Oaki , Koki Yamane , Koki Inami , Sho Sakaino

Scientists use mathematical modelling to understand and predict the properties of complex physical systems. In highly parameterised models there often exist relationships between parameters over which model predictions are identical, or…

Data Analysis, Statistics and Probability · Physics 2017-03-24 Dhruva V. Raman , James Anderson , Antonis Papachristodoulou

Particle-based shape modeling (PSM) is a popular approach to automatically quantify shape variability in populations of anatomies. The PSM family of methods employs optimization to automatically populate a dense set of corresponding…

Computer Vision and Pattern Recognition · Computer Science 2024-11-26 Hong Xu , Shireen Y. Elhabian

Tumor saliency estimation aims to localize tumors by modeling the visual stimuli in medical images. However, it is a challenging task for breast ultrasound due to the complicated anatomic structure of the breast and poor image quality; and…

Computer Vision and Pattern Recognition · Computer Science 2019-06-20 Fei Xu , Yingtao Zhang , Min Xian , H. D. Cheng , Boyu Zhang , Jianrui Ding , Chunping Ning , Ying Wang

Parameter estimation is a major challenge in computational modeling of biological processes. This is especially the case in image-based modeling where the inherently quantitative output of the model is measured against image data, which is…

Quantitative Methods · Quantitative Biology 2018-07-27 Diana Barac , Michael D. Multerer , Dagmar Iber

Computational inverse problems for biomedical simulators suffer from limited data and relatively high parameter dimensionality. This often requires sensitivity analysis, where parameters of the model are ranked based on their influence on…

Tissues and Organs · Quantitative Biology 2025-06-06 Mitchel J. Colebank