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Fluorescence microscopy is essential in biological and medical research, providing critical insights into cellular structures. However, limited by optical diffraction and background noise, a substantial amount of hidden information is still…

Biological Physics · Physics 2026-04-14 Xiaofeng Zhang , Yongsheng Huang , Jielong Yang , Zhili Wang , Si Chen , Linbo Liu , Xin Ge

Polarimetric imaging is one of the most effective techniques for high-contrast imaging and characterization of circumstellar environments. These environments can be characterized through direct-imaging polarimetry at near-infrared…

Instrumentation and Methods for Astrophysics · Physics 2021-09-29 Laurence Denneulin , Maud Langlois , Éric Thiébaut , Nelly Pustelnik

When the inverse problem of diffuse optical tomography (DOT) is solved with the Born or Rytov approximation, the size of the matrix of the linear inverse problem becomes large if the volume (or area) of the domain in biological tissue used…

Medical Physics · Physics 2021-07-22 Tetsuya Mimura , Yu Jiang , Norikazu Todoroki , Manabu Machida

We report the experimental super-resolution of pairs of point-like fluorescent sources using a modified image inversion interferometer microscope. The technique is inspired by recent developments in the application of quantum parameter…

Proton radiography is a central diagnostic technique for measuring electromagnetic (EM) fields in high-energy-density, laser-produced plasmas. In this technique, protons traverse the plasma where they accumulate small EM deflections which…

Electrical impedance tomography (EIT) is an imaging modality in which the conductivity distribution inside a target is reconstructed based on voltage measurements from the surface of the target. Reconstructing the conductivity distribution…

Mathematical Physics · Physics 2012-07-05 Antti Lipponen , Aku Seppänen , Jari Kaipio

Diffuse optical tomography (DOT) is an imaging modality which uses near-infrared light. Although iterative numerical schemes are commonly used for its inverse problem, correct solutions are not obtained unless good initial guesses are…

Numerical Analysis · Mathematics 2021-06-07 Yu Jiang , Manabu Machida , Norikazu Todoroki

Photo-acoustic tomography is a newly developed hybrid imaging modality that combines a high-resolution modality with a high-contrast modality. We analyze the reconstruction of diffusion and absorption parameters in an elliptic equation and…

Analysis of PDEs · Mathematics 2015-06-04 Jie Chen , Yang Yang

Polarization-resolved near-infrared imaging adds a useful optical contrast mechanism to eye tracking by measuring the polarization state of light reflected by ocular tissues in addition to its intensity. In this paper we demonstrate how…

Diffuse optical tomography (DOT) has been investigated as an alternative imaging modality for breast cancer detection thanks to its excellent contrast to hemoglobin oxidization level. However, due to the complicated non-linear photon…

Computer Vision and Pattern Recognition · Computer Science 2019-09-10 Jaejun Yoo , Sohail Sabir , Duchang Heo , Kee Hyun Kim , Abdul Wahab , Yoonseok Choi , Seul-I Lee , Eun Young Chae , Hak Hee Kim , Young Min Bae , Young-wook Choi , Seungryong Cho , Jong Chul Ye

We deal with the problem of determining the shape of an inclusion embedded in a homogenous background medium. The multifre-quency electrical impedance tomography is used to image the inclusion. For different frequencies, a current is…

Analysis of PDEs · Mathematics 2019-03-21 Jin Cheng , Mourad Choulli , Shuai Lu

Purpose: Optical imaging is evolving as a key technique for advanced sensing in the operating room. Recent research has shown that machine learning algorithms can be used to address the inverse problem of converting pixel-wise multispectral…

We consider the inverse problem of determining an optical mask that produces a desired circuit pattern in photolithography. We set the problem as a shape design problem in which the unknown is a two-dimensional domain. The relationship…

Analysis of PDEs · Mathematics 2017-02-14 Luca Rondi , Fadil Santosa

Optimal Transport is a useful metric to compare probability distributions and to compute a pairing given a ground cost. Its entropic regularization variant (eOT) is crucial to have fast algorithms and reflect fuzzy/noisy matchings. This…

Statistics Theory · Mathematics 2024-03-12 Francisco Andrade , Gabriel Peyre , Clarice Poon

Allying high-resolution with a large field-of-view (FOV) is of great importance in the fields of biology and medicine, but particularly challenging when imaging non-flat living samples such as the human retina. Indeed, high-resolution is…

We study an inverse initial source problem that models Photoacoustic tomography measurements with array detectors, and introduce a method that can be viewed as a modification of the so called back and forth nudging method. We show that the…

Analysis of PDEs · Mathematics 2016-11-23 Olga Chervova , Lauri Oksanen

Diffusion models have recently demonstrated notable success in solving inverse problems. However, current diffusion model-based solutions typically require a large number of function evaluations (NFEs) to generate high-quality images…

Computer Vision and Pattern Recognition · Computer Science 2024-12-06 Tianyu Chen , Zhendong Wang , Mingyuan Zhou

Fluorescence Molecular Tomography (FMT) is a promising technique for non-invasive 3D visualization of fluorescent probes, but its reconstruction remains challenging due to the inherent ill-posedness and reliance on inaccurate or…

Image and Video Processing · Electrical Eng. & Systems 2025-11-07 Shihan Zhao , Jianru Zhang , Yanan Wu , Linlin Li , Siyuan Shen , Xingjun Zhu , Guoyan Zheng , Jiahua Jiang , Wuwei Ren

In the previous paper "Stabilizing Inverse Problems by Internal Data", the authors introduced a simple procedure that allows one to detect whether and explain why internal information arising in several novel coupled physics (hybrid)…

Analysis of PDEs · Mathematics 2014-11-04 Peter Kuchment , Dustin Steinhauer

In this paper we the formulation of inverse problems as constrained minimization problems and their iterative solution by gradient or Newton type. We carry out a convergence analysis in the sense of regularization methods and discuss…

Numerical Analysis · Mathematics 2021-01-15 Barbara Kaltenbacher , Kha Van Huynh