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We demonstrate in vivo endoscopic optical coherence tomography (OCT) imaging in the forward direction using a flexible fiber bundle. In comparison to current conventional forward looking probe schemes, our approach simplifies the endoscope…

Photolithography is a process in the production of integrated circuits in which a mask is used to create an exposed pattern with a desired geometric shape. In the inverse problem of photolithography, a desired pattern is given and the mask…

Analysis of PDEs · Mathematics 2016-01-18 Luca Rondi , Fadil Santosa , Zhu Wang

In the framework of quantum optics, we study the problem of goodness-of-fit testing in a severely ill-posed inverse problem. A novel testing procedure is introduced and its rates of convergence are investigated under various smoothness…

Statistics Theory · Mathematics 2008-12-22 Katia Meziani

An image-based technique for measuring the complex field in the pupil of an imaging system is presented. Two point source images, one with a small modification introduced in the pupil, are combined using a simple and non-iterative…

Optics · Physics 2013-09-27 Johanan L. Codona

Fluorescence microscopy is an important and extensively utilised tool for imaging biological systems. However, the image resolution that can be obtained has a limit as defined through the laws of diffraction. Demand for improved resolution…

Biological Physics · Physics 2007-08-27 James H. Rice

High-numerical-aperture optical coherence tomography (OCT) enables sub-cellular imaging but faces a trade-off between lateral resolution and depth of focus. Computational refocusing can correct defocus in Fourier-domain OCT, yet its…

Optics · Physics 2026-05-22 Yue Zhu , Shuichi Makita , Naoki Fukutake , Yoshiaki Yasuno

Fluorescence lifetime imaging microscopy (FLIM) is an important technique to understand the chemical micro-environment in cells and tissues since it provides additional contrast compared to conventional fluorescence imaging. When two…

Image and Video Processing · Electrical Eng. & Systems 2022-01-19 Varun Mannam , Xiaotong Yuan , Scott Howard

Polarimetry and optical imaging techniques face challenges in photon-starved scenarios, where the low number of detected photons imposes a trade-off between image resolution, integration time, and sample sensitivity. Here we introduce a…

In optical tomography a physical body is illuminated with near-infrared light and the resulting outward photon flux is measured at the object boundary. The goal is to reconstruct internal optical properties of the body, such as absorption…

Numerical Analysis · Mathematics 2016-01-20 Antti Hannukainen , Lauri Harhanen , Nuutti Hyvönen , Helle Majander

Traditional full-field optical coherence tomography (FF-OCT) is effective for rapid cross-sectional imaging but often suffers from incoherent signals due to imbalanced light intensities between the sample and reference arms. While the…

Optics · Physics 2024-10-17 Youlong Fan , Qingye Hu , Zhongping Wang , Zengming Zhang , Xiantao Wei

We consider the inverse problem of in-line holography, applied to minimally-destructive imaging of cold atom clouds. Absorption imaging near-resonance provides a simple, but destructive measurement of atom column density. Imaging off…

Atomic Physics · Physics 2009-11-11 L. D. Turner , K. F. E. M. Domen , R. E. Scholten

Optical diffraction tomography (ODT) is an emerging 3D imaging technique that is used for the 3D reconstruction of the refractive index (RI) for semi-transparent samples. Various inverse models have been proposed to reconstruct the 3D RI…

Optics · Physics 2022-06-13 Ahmed B. Ayoub , Amirhossein Saba , Carlo Gigli , Demetri Psaltis

Inverse ellipsometry, i.e., reconstructing optical constants and film thickness from the measured phase difference $\Delta$ and amplitude ratio $\Psi$, is a fundamentally ill-posed problem. Traditional solutions rely on slow, expert-driven…

Machine Learning · Computer Science 2026-03-20 Yiming Ma , Jianzhi Teng , Xinjie Li , Xin Sun , Zhiyong Wang , Yuzhou Song , Lionel Z. Wang , Bin Chen

Fourier ptychography microscopy (FPM), sharing its roots with synthetic aperture technique and phase retrieval method, is a recently developed computational microscopic super-resolution technique. By turning on the light-emitting diode…

Optics · Physics 2021-05-07 G. Zhou , S. Zhang , C. Zheng , T. Li , Y. Hu , Q. Hao

Fourier ptychography (FP) imaging, drawing on the idea of synthetic aperture, has been demonstrated as a potential approach for remote sub-diffraction-limited imaging. Nevertheless, the farthest imaging distance is still limited around 10 m…

Fluorescence detection, either involving propagating or near-field emission, is widely being used in spectroscopy, sensing and microscopy. Total internal reflection fluorescence (TIRF) confines fluorescence excitation by an evanescent…

Quantitative Methods · Quantitative Biology 2020-06-24 Martin Oheim , Adi Salomon , Maia Brunstein

Oblique plane microscopy is a method enabling light-sheet fluorescence imaging through a single microscope objective lens by focusing on a tilted plane within the sample. To focus the fluorescence emitted by the oblique plane on a camera,…

In image deconvolution problems, the diagonalization of the underlying operators by means of the FFT usually yields very large speedups. When there are incomplete observations (e.g., in the case of unknown boundaries), standard…

Computer Vision and Pattern Recognition · Computer Science 2016-08-31 Miguel Simões , Luis B. Almeida , José Bioucas-Dias , Jocelyn Chanussot

The Rytov approximation has been commonly used to obtain reconstructed images for optical tomography. However, the method requires linearization of the nonlinear inverse problem. Here, we demonstrate nonlinear Rytov approximations by…

Medical Physics · Physics 2024-11-26 Chi Zhang , Manabu Machida

The polarization tomography problem consists of recovering a matrix function f from the fundamental matrix of the equation $D\eta/dt=\pi_{\dot\gamma}f\eta$ known for every geodesic $\gamma$ of a given Riemannian metric. Here…

Mathematical Physics · Physics 2009-11-13 Roman Novikov , Vladimir Sharafutdinov
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