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Masked Autoencoder~(MAE) is a prevailing self-supervised learning method that achieves promising results in model pre-training. However, when the various downstream tasks have data distributions different from the pre-training data, the…
RNA-Seq data characteristically exhibits large variances, which need to be appropriately accounted for in the model. We first explore the effects of this variability on the maximum likelihood estimator (MLE) of the overdispersion parameter…
We present a new method of transient point source deconvolution for coded-aperture X-Ray detectors. Our method is based upon the calculation of the likelihood function and its interpretation as a probability density for the transient source…
The Morris-Lecar (ML) model has applications to neuroscience and cognition. A simple network consisting of a pair of synaptically coupled ML neurons can exhibit a wide variety of deterministic behaviors including asymmetric amplitude state…
Bayesian observer and actor models have provided normative explanations for many behavioral phenomena in perception, sensorimotor control, and other areas of cognitive science and neuroscience. They attribute behavioral variability and…
Object-centric representations form the basis of human perception, and enable us to reason about the world and to systematically generalize to new settings. Currently, most works on unsupervised object discovery focus on slot-based…
Sampling-based motion planning under task constraints is challenging because the null-measure constraint manifold in the configuration space makes rejection sampling extremely inefficient, if not impossible. This paper presents a…
Variational autoencoders (VAEs) employ Bayesian inference to interpret sensory inputs, mirroring processes that occur in primate vision across both ventral (Higgins et al., 2021) and dorsal (Vafaii et al., 2023) pathways. Despite their…
In Part I (arXiv:1911.00619) of this article, we proposed an importance sampling algorithm to compute rare-event probabilities in forward uncertainty quantification problems. The algorithm, which we termed the "Bayesian Inverse Monte Carlo…
In a traditional Gaussian graphical model, data homogeneity is routinely assumed with no extra variables affecting the conditional independence. In modern genomic datasets, there is an abundance of auxiliary information, which often gets…
Tumor samples are heterogeneous. They consist of different subclones that are characterized by differences in DNA nucleotide sequences and copy numbers on multiple loci. Heterogeneity can be measured through the identification of the…
Bayesian inference for inverse problems involves computing expectations under posterior distributions -- e.g., posterior means, variances, or predictive quantities -- typically via Monte Carlo (MC) estimation. When the quantity of interest…
This work considers sequential edge-promoting Bayesian experimental design for (discretized) linear inverse problems, exemplified by X-ray tomography. The process of computing a total variation type reconstruction of the absorption inside…
Metallicity can be measured by analyzing the spectra in the X-ray region and comparing the flux in spectral lines to the flux in the underlying Bremsstrahlung continuum. In this paper we propose new Bayesian methods which directly model the…
Perception, in theoretical neuroscience, has been modeled as the encoding of external stimuli into internal signals, which are then decoded. The Bayesian mean is an important decoder, as it is optimal for purposes of both estimation and…
Many physical systems exhibit a low-dimensional structure that varies with external parameters: link lengths in a robot, forcing constants in a fluid, or Reynolds numbers in a flow shift the underlying manifold while preserving its…
We propose a computational model of visual search that incorporates Bayesian interpretations of the neural mechanisms that underlie categorical perception and saccade planning. To enable meaningful comparisons between simulated and human…
Fair and unbiased machine learning is an important and active field of research, as decision processes are increasingly driven by models that learn from data. Unfortunately, any biases present in the data may be learned by the model,…
This paper describes a Bayesian statistical method for determining the genetic basis of a complex genetic trait. The method uses a sample of unrelated individuals classified into two groups, for example cases and controls. Each group is…
The aim of magnetorelaxometry imaging is to determine the distribution of magnetic nanoparticles inside a subject by measuring the relaxation of the superposition magnetic field generated by the nanoparticles after they have first been…