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The segmentation of lesions in Moderate to Severe Traumatic Brain Injury (msTBI) presents a significant challenge in neuroimaging due to the diverse characteristics of these lesions, which vary in size, shape, and distribution across brain…

Computer Vision and Pattern Recognition · Computer Science 2025-04-10 Constantin Ulrich , Tassilo Wald , Fabian Isensee , Klaus H. Maier-Hein

In this paper, we introduce a new dataset in the medical field of Traumatic Brain Injury (TBI), called TBI-IT, which includes both electronic medical records (EMRs) and head CT images. This dataset is designed to enhance the accuracy of…

Image and Video Processing · Electrical Eng. & Systems 2024-03-15 Jie Li , Jiaying Wen , Tongxin Yang , Fenglin Cai , Miao Wei , Zhiwei Zhang , Li Jiang

Traumatic Brain Injuries (TBIs) are a pressing global public health issue, impacting tens of millions of individuals annually. Vulnerable road users (VRUs), such as pedestrians, are vastly overrepresented in the worldwide TBI statistics. To…

Numerical Analysis · Mathematics 2025-04-23 Natalia Lindgren , Svein Kleiven , Xiaogai Li

Machine learning head models (MLHMs) are developed to estimate brain deformation for early detection of traumatic brain injury (TBI). However, the overfitting to simulated impacts and the lack of generalizability caused by distributional…

Background: Traumatic brain injury modeling requires integrating volumetric neuroimaging, demographic parameters, and acquisition metadata. Finite element solvers are too computationally expensive for clinical settings. Neural operators…

Machine Learning · Computer Science 2026-04-27 Anusha Agarwal , Dibakar Roy Sarkar , Somdatta Goswami

This report describes technical adaptations of a traumatic brain injury (TBI) model-largely inspired by Marmarou-in order to monitor microdialysis data and PtiO2 (brain tissue oxygen) before, during and after injury. We particularly…

Neurons and Cognition · Quantitative Biology 2007-07-31 Emilie Carré , Emmanuel Cantais , Olivier Darbin , Jean-Pierre Terrier , Michel Lonjon , Bruno Palmier , Jean-Jacques Risso

Mild traumatic brain injury (mTBI) often results from violent head motion or impact. Most prevention strategies explicitly or implicitly rely on motion- or deformation-based injury criteria, both of which require accurate measurements of…

Applied Physics · Physics 2025-08-12 Yang Wan , Benjamin E. Grossman-Ponemona , Haneesh Kesari

The Federal Interagency Traumatic Brain Injury Research (FITBIR) database is a centralized data repository for traumatic brain injury (TBI) research. It includes over 45,529 magnetic resonance images (MRI) from 6,211 subjects (9,229 imaging…

Mild traumatic brain injury (mTBI, also known as concussion) caused by the head impact is a crucial global public health problem, but the physics of mTBI is still unclear. During the impact, the rapid movement of the head injures the brain,…

Mild Traumatic Brain Injury (mTBI) is a common brain injury and affects a diverse group of people: soldiers, constructors, athletes, drivers, children, elders, and nearly everyone. Thus, having a well-established, fast, cheap, and accurate…

Signal Processing · Electrical Eng. & Systems 2022-08-19 Weiqing Gu , Ryan Chang , Bohan Yang

Post-traumatic epilepsy (PTE) is a life-long complication of traumatic brain injury (TBI) and is a major public health problem that has an estimated incidence that ranges from 2%-50%, depending on the severity of the TBI. Currently, the…

Quantitative Methods · Quantitative Biology 2020-11-17 Md Navid Akbar , Marianna La Rocca , Rachael Garner , Dominique Duncan , Deniz Erdoğmuş

Brain injuries resulting from mechanical trauma represent an ongoing global public health issue. Several $\textit{in vitro}$ and $\textit{in vivo}$ models for traumatic brain injury (TBI) continue to be developed for delineating the various…

Biological Physics · Physics 2023-08-28 Yang Wan , Rafael D. González-Cruz , Diane Hoffman-Kim , Haneesh Kesari

The aim was to investigate mechanical and functional failure of diffuse axonal injury (DAI) in nerve bundles following frontal head impacts, by finite element simulations. Anatomical changes following traumatic brain injury are simulated at…

Tissues and Organs · Quantitative Biology 2020-09-02 Ilaria Cinelli , Michel Destrade , Peter McHugh , Antonia Trotta , Michael Gilchrist , Maeve Duffy

Impact induced traumatic brain injury (ITBI) describes brain injury from head impact not necessarily accompanied by skull fracture. For sufficiently abrupt head impact decelerations, ITBI results from brain tissue stress incurred as the…

Medical Physics · Physics 2009-04-21 Eric G. Blackman

Traumatic Brain Injury (TBI) is a major contributor to mortality among older adults, with geriatric patients facing disproportionately high risk due to age-related physiological vulnerability and comorbidities. Early and accurate prediction…

Quantitative Methods · Quantitative Biology 2025-05-23 Yong Si , Junyi Fan , Li Sun , Shuheng Chen , Elham Pishgar , Kamiar Alaei , Greg Placencia , Maryam Pishgar

The midline related pathological image features are crucial for evaluating the severity of brain compression caused by stroke or traumatic brain injury (TBI). The automated midline delineation not only improves the assessment and clinical…

Image and Video Processing · Electrical Eng. & Systems 2020-02-28 Shen Wang , Kongming Liang , Chengwei Pan , Chuyang Ye , Xiuli Li , Feng Liu , Yizhou Yu , Yizhou Wang

Mild traumatic brain injuries (mTBI) are a highly prevalent condition with heterogeneous outcomes between individuals. A key factor governing brain tissue deformation and the risk of mTBI is the rotational kinematics of the head.…

Patients with traumatic brain injury (TBI) often experience pathological increases in intracranial pressure (ICP), leading to intracranial hypertension (tIH), a common and serious complication. Early warning of an impending rise in ICP…

Mild Traumatic Brain Injury (mTBI) is a significant public health challenge due to its high prevalence and potential for long-term health effects. Despite Computed Tomography (CT) being the standard diagnostic tool for mTBI, it often yields…

Image and Video Processing · Electrical Eng. & Systems 2024-04-09 Hanem Ellethy , Viktor Vegh , Shekhar S. Chandra

During severe impact conditions, brain tissue experiences a rapid and complex deformation, which can be seen as a mixture of compression, tension and shear. Moreover, diffuse axonal injury (DAI) occurs in animals and humans when both the…

Soft Condensed Matter · Physics 2020-09-04 Badar Rashid , Michel Destrade , Michael D. Gilchrist