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An abdominal aortic aneurysm (AAA) is an enlargement of the abdominal aorta which, if left untreated, can progressively widen and may rupture with fatal consequences. In this paper, we determine an optimal treatment policy using Markov…

Systems and Control · Computer Science 2016-11-08 Robert Mattila , Antti Siika , Joy Roy , Bo Wahlberg

In this paper, an uplink scheduling policy problem to minimize the network latency, defined as the air-time to serve all of users with a quality-of-service (QoS), under an energy constraint is considered in a training-based large-scale…

Information Theory · Computer Science 2016-07-27 Kyung Jun Choi , Kwang Soon Kim

Healthcare programs such as Medicaid provide crucial services to vulnerable populations, but due to limited resources, many of the individuals who need these services the most languish on waiting lists. Survival models, e.g. the Cox…

Machine Learning · Computer Science 2020-10-15 Kamrun Naher Keya , Rashidul Islam , Shimei Pan , Ian Stockwell , James R. Foulds

Multi-arm trials are gaining interest in practice given the statistical and logistical advantages they can offer. The standard approach uses a fixed allocation ratio, but there is a call for making it adaptive and skewing the allocation of…

Methodology · Statistics 2026-01-16 Gianmarco Caruso , Pavel Mozgunov

Kidney transplantation is the most effective renal replacement therapy for end stage renal disease patients. With the severe shortage of kidney supplies and for the clinical effectiveness of transplantation, patient's life expectancy post…

Methodology · Statistics 2023-10-19 Ge Zhao , Yanyuan Ma , Huazhen Lin , Yi Li

Kidney transplantation can significantly enhance living standards for people suffering from end-stage renal disease. A significant factor that affects graft survival time (the time until the transplant fails and the patient requires another…

Machine Learning · Computer Science 2022-07-07 Mohammadreza Nemati , Haonan Zhang , Michael Sloma , Dulat Bekbolsynov , Hong Wang , Stanislaw Stepkowski , Kevin S. Xu

Lung cancer is the primary cause of cancer-related mortality, claiming approximately 1.79 million lives globally in 2020, with an estimated 2.21 million new cases diagnosed within the same period. Among these, Non-Small Cell Lung Cancer…

Quantitative Methods · Quantitative Biology 2024-02-16 Mahtab Darvish , Ryan Trask , Patrick Tallon , Mélina Khansari , Lei Ren , Michelle Hershman , Bardia Yousefi

The efficient and fair allocation of limited resources is a classical problem in economics and computer science. In kidney exchanges, a central market maker allocates living kidney donors to patients in need of an organ. Patients and donors…

Artificial Intelligence · Computer Science 2020-05-21 Rachel Freedman , Jana Schaich Borg , Walter Sinnott-Armstrong , John P. Dickerson , Vincent Conitzer

Algorithmic predictions are emerging as a promising solution concept for efficiently allocating societal resources. Fueling their use is an underlying assumption that such systems are necessary to identify individuals for interventions. We…

Machine Learning · Computer Science 2024-06-21 Ali Shirali , Rediet Abebe , Moritz Hardt

Randomization is a common technique used in clinical trials to eliminate potential bias and confounders in a patient population. Equal allocation to treatment groups is the standard due to its optimal efficiency in many cases. However, in…

Applications · Statistics 2020-04-09 Thevaa Chandereng , Xiaodan Wei , Rick Chappell

Smoking is one of the preventable threats to human health and is a major risk factor for lung cancer, upper aero-digestive cancer, and chronic obstructive pulmonary disease. Estimating and forecasting the smoking attributable fraction (SAF)…

Applications · Statistics 2019-10-29 Yicheng Li , Adrian E. Raftery

We study the design of multi-armed parallel group clinical trials to estimate personalized treatment rules that identify the best treatment for a given patient with given covariates. Assuming that the outcomes in each treatment arm are…

Statistics Theory · Mathematics 2022-07-13 David Azriel , Yosef Rinott , Martin Posch

Background: Many authors have described MELD as a predictor of short-term mortality in the liver transplantation waiting list. However MELD score accuracy to predict long term mortality has not been statistically evaluated. Objective: The…

The burgeoning need for kidney transplantation mandates immediate attention. Mismatch of deceased donor-recipient kidney leads to post-transplant death. To ensure ideal kidney donor-recipient match and minimize post-transplant deaths, the…

Computers and Society · Computer Science 2019-08-22 Ehsan Khan , Avishek Choudhury , Amy L Friedman , Daehan Won

The study of disparities in the liver transplantation process may focus on quantifying causal effects, particularly the average, direct, or indirect effects of various social determinants of health on being listed as a candidate for…

Allocation of scarce resources is a recurring challenge for the public sector: something that emerges in areas as diverse as healthcare, disaster recovery, and social welfare. The complexity of these policy domains and the need for meeting…

Computers and Society · Computer Science 2023-10-11 Saba Esnaashari , Jonathan Bright , John Francis , Youmna Hashem , Vincent Straub , Deborah Morgan

In this paper, we provide some general convergence results for adaptive designs for treatment comparison, both in the absence and presence of covariates. In particular, we demonstrate the almost sure convergence of the treatment allocation…

Methodology · Statistics 2015-06-01 Alessandro Baldi Antognini , Maroussa Zagoraiou

We propose a dynamic allocation procedure that increases power and efficiency when measuring an average treatment effect in sequential randomized trials. Subjects arrive iteratively and are either randomized or paired via a matching…

Methodology · Statistics 2013-05-23 Adam Kapelner , Abba Krieger

The availability of downstream resources plays is critical in planning the admission of elective surgery patients. The most crucial one is inpatient beds. To ensure bed availability, hospitals may use machine learning (ML) models to predict…

Machine Learning · Computer Science 2025-07-30 Pieter Smet , Martina Doneda , Ettore Lanzarone , Giuliana Carello

Prognostication for lung cancer, a leading cause of mortality, remains a complex task, as it needs to quantify the associations of risk factors and health events spanning a patient's entire life. One challenge is that an individual's…

Machine Learning · Statistics 2025-08-28 Stephen Salerno , Yi Li