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We present a high-level domain-specific language (DSL) interface to drive an adaptive incomplete $k$-d tree-based framework for finite element (FEM) solutions to PDEs. This DSL provides three key advances: (a) it abstracts out the…

Computational Engineering, Finance, and Science · Computer Science 2023-06-01 Eric Heisler , Cheng-Hau Yang , Aadesh Deshmukh , Baskar Ganapathysubramanian , Hari Sundar

Recent progress in scientific machine learning (SciML) has opened up the possibility of training novel neural network architectures that solve complex partial differential equations (PDEs). Several (nearly data free) approaches have been…

Machine-learning-based interatomic potential energy surface (PES) models are revolutionizing the field of molecular modeling. However, although much faster than electronic structure schemes, these models suffer from costly computations via…

Computational Physics · Physics 2022-08-08 Denghui Lu , Wanrun Jiang , Yixiao Chen , Linfeng Zhang , Weile Jia , Han Wang , Mohan Chen

Conventional molecular dynamics (MD) simulation approaches, such as $\textit{ab initio}$ MD (AIMD) and empirical force field MD (EFFMD), face significant trade-offs between physical accuracy and computational efficiency. This work presents…

Disordered Systems and Neural Networks · Physics 2026-05-12 Hongyu Yan , Yong Wei , Minghan Chen , Hanning Chen

Foundation models (FMs) exhibit remarkable generalization but require adaptation to downstream tasks, particularly in privacy-sensitive applications. Due to data privacy regulations, cloud-based FMs cannot directly access private edge data,…

Machine Learning · Computer Science 2025-08-25 Guangyu Sun , Jingtao Li , Weiming Zhuang , Chen Chen , Chen Chen , Lingjuan Lyu

Molecular property prediction refers to the task of labeling molecules with some biochemical properties, playing a pivotal role in the drug discovery and design process. Recently, with the advancement of machine learning, deep…

Molecular Networks · Quantitative Biology 2024-01-10 Zeyu Wang , Tianyi Jiang , Jinhuan Wang , Qi Xuan

The potential energy surface (PES) is crucial for interpreting a variety of chemical reaction processes. However, predicting accurate PESs with high-level electronic structure methods is a challenging task due to the high computational…

Chemical Physics · Physics 2022-06-09 Yanxian Tao , Xiongzhi Zeng , Yi Fan , Jie Liu , Zhenyu Li , Jinlong Yang

The potential energy surface (PES) of molecules with respect to their nuclear positions is a primary tool in understanding chemical reactions from first principles. However, obtaining this information is complicated by the fact that…

The unprecedented amount of data generated from experiments, field observations, and large-scale numerical simulations at a wide range of spatio-temporal scales have enabled the rapid advancement of data-driven and especially deep learning…

Computational Physics · Physics 2024-06-19 Suraj Pawar , Omer San , Aditya Nair , Adil Rasheed , Trond Kvamsdal

We explore the performance of a statistical learning technique based on Gaussian Process (GP) regression as an efficient non-parametric method for constructing multi-dimensional potential energy surfaces (PES) for polyatomic molecules.…

Chemical Physics · Physics 2016-11-23 Jie Cui , Roman V. Krems

Modelling complex physical systems through partial differential equations (PDEs) is central to many disciplines in science and engineering. Yet in most real applications, unknown or incomplete relationships such as constitutive or thermal…

Computational Engineering, Finance, and Science · Computer Science 2026-01-08 Ado Farsi , Nacime Bouziani , David A Ham

We present a machine-learning strategy for finite element analysis of solid mechanics wherein we replace complex portions of a computational domain with a data-driven surrogate. In the proposed strategy, we decompose a computational domain…

Numerical Analysis · Mathematics 2023-10-24 Eric Parish , Payton Lindsay , Timothy Shelton , John Mersch

Highly accurate force fields are a mandatory requirement to generate predictive simulations. In this regard, Machine Learning Force Fields (MLFFs) have emerged as a revolutionary approach in computational chemistry and materials science,…

Materials Science · Physics 2025-03-11 Carlos A. Vital , Román J. Armenta-Rico , Huziel E. Sauceda

Recent developments in 3D vision have enabled significant progress in inferring neural fluid fields and realistic rendering of fluid dynamics. However, these methods require dense captures of real-world flows, which demand specialized…

Machine Learning · Computer Science 2026-02-23 Yuqiu Liu , Jingxuan Xu , Mauricio Soroco , Yunchao Wei , Wuyang Chen

We present a novel approach to modeling the ground state mass of atomic nuclei based directly on a probabilistic neural network constrained by relevant physics. Our Physically Interpretable Machine Learning (PIML) approach incorporates…

Nuclear Theory · Physics 2022-08-17 M. R. Mumpower , T. M. Sprouse , A. E. Lovell , A. T. Mohan

The task of locating first order saddle points on high-dimensional surfaces describing the variation of energy as a function of atomic coordinates is an essential step for identifying the mechanism and estimating the rate of thermally…

Chemical Physics · Physics 2025-07-24 Rohit Goswami , Maxim Masterov , Satish Kamath , Alejandro Peña-Torres , Hannes Jónsson

Reconstructing force fields (FFs) from atomistic simulation data is a challenge since accurate data can be highly expensive. Here, machine learning (ML) models can help to be data economic as they can be successfully constrained using the…

Chemical Physics · Physics 2022-10-27 Niklas Frederik Schmitz , Klaus-Robert Müller , Stefan Chmiela

A dynamic mixed super-resolution model (DMSRM) for large-eddy simulations (LESs) is proposed, which combines the traditional dynamic mixed model (DMM) formulation with the generation of super-resolved velocity fields from which the…

The enormous structural and chemical diversity of metal-organic frameworks (MOFs) forces researchers to actively use simulation techniques on an equal footing with experiments. MOFs are widely known for outstanding adsorption properties, so…

Materials Science · Physics 2021-11-22 Vadim V. Korolev , Yurii M. Nevolin , Thomas A. Manz , Pavel V. Protsenko

The development of coarse-grained (CG) molecular models typically requires a time-consuming iterative tuning of parameters in order to have the approximated CG models behaving correctly and consistently with, e.g., available…