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Related papers: Multiple Model-Free Knockoffs

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Although there is a huge literature on feature selection for the Cox model, none of the existing approaches can control the false discovery rate (FDR) unless the sample size tends to infinity. In addition, there is no formal power analysis…

Methodology · Statistics 2023-08-02 Daoji Li , Jinzhao Yu , Hui Zhao

This paper introduces an innovative method for conducting conditional independence testing in high-dimensional data, facilitating the automated discovery of significant associations within distinct subgroups of a population, all while…

Methodology · Statistics 2023-09-19 Matteo Sesia , Tianshu Sun

We address challenges in variable selection with highly correlated data that are frequently present in finance, economics, but also in complex natural systems as e.g. weather. We develop a robustified version of the knockoff framework,…

Econometrics · Economics 2022-06-14 Konstantin Görgen , Abdolreza Nazemi , Melanie Schienle

We present a novel method for controlling the $k$-familywise error rate ($k$-FWER) in the linear regression setting using the knockoffs framework first introduced by Barber and Cand\`es. Our procedure, which we also refer to as knockoffs,…

Methodology · Statistics 2015-11-10 Lucas Janson , Weijie Su

In modern scientific research, the objective is often to identify which variables are associated with an outcome among a large class of potential predictors. This goal can be achieved by selecting variables in a manner that controls the the…

Methodology · Statistics 2023-10-10 Yushu Shi , Michael Martens

We tackle the problem of selecting from among a large number of variables those that are 'important' for an outcome. We consider situations where groups of variables are also of interest in their own right. For example, each variable might…

Methodology · Statistics 2018-08-13 Eugene Katsevich , Chiara Sabatti

This paper introduces a machine for sampling approximate model-X knockoffs for arbitrary and unspecified data distributions using deep generative models. The main idea is to iteratively refine a knockoff sampling mechanism until a criterion…

Methodology · Statistics 2020-03-03 Yaniv Romano , Matteo Sesia , Emmanuel J. Candès

One limitation of the most statistical/machine learning-based variable selection approaches is their inability to control the false selections. A recently introduced framework, model-x knockoffs, provides that to a wide range of models but…

Machine Learning · Statistics 2025-09-03 Deniz Koyuncu , Alex Gittens , Bülent Yener

False discovery rate (FDR) controlling procedures provide important statistical guarantees for the replicability in signal identification based on multiple hypotheses testing. In many fields of study, FDR controlling procedures are used in…

Methodology · Statistics 2022-10-04 Ran Dai , Cheng Zheng

Continuous improvement in medical imaging techniques allows the acquisition of higher-resolution images. When these are used in a predictive setting, a greater number of explanatory variables are potentially related to the dependent…

Statistics Theory · Mathematics 2019-03-13 Tuan-Binh Nguyen , Jérôme-Alexis Chevalier , Bertrand Thirion

Consider a case-control study in which we have a random sample, constructed in such a way that the proportion of cases in our sample is different from that in the general population---for instance, the sample is constructed to achieve a…

Methodology · Statistics 2019-01-01 Rina Foygel Barber , Emmanuel Candes

The fixed-X knockoff filter is a flexible framework for variable selection with false discovery rate (FDR) control in linear models with arbitrary design matrices (of full column rank) and it allows for finite-sample selective inference via…

Statistics Theory · Mathematics 2023-11-28 Mehrdad Pournaderi , Yu Xiang

This paper develops a method based on model-X knockoffs to find conditional associations that are consistent across diverse environments, controlling the false discovery rate. The motivation for this problem is that large data sets may…

Methodology · Statistics 2021-06-09 Shuangning Li , Matteo Sesia , Yaniv Romano , Emmanuel Candès , Chiara Sabatti

Conditional independence testing (CIT) is essential for reliable scientific discovery. It prevents spurious findings and enables controlled feature selection. Recent CIT methods have used machine learning (ML) models as surrogates of the…

Statistics Theory · Mathematics 2026-02-02 Angel Reyero-Lobo , Bertrand Thirion , Pierre Neuvial

We consider the problem of variable selection in regression models. In particular, we are interested in selecting explanatory covariates linked with the response variable and we want to determine which covariates are relevant, that is which…

Methodology · Statistics 2019-07-09 Anne Gégout-Petit , Aurélie Gueudin-Muller , Clémence Karmann

Power and reproducibility are key to enabling refined scientific discoveries in contemporary big data applications with general high-dimensional nonlinear models. In this paper, we provide theoretical foundations on the power and robustness…

Statistics Theory · Mathematics 2017-09-04 Yingying Fan , Emre Demirkaya , Gaorong Li , Jinchi Lv

We propose a novel multiple testing methodology for controlling the false discovery rate (FDR) in high-dimensional linear models that integrates model-X knockoff techniques with debiased penalized regression estimators. At the foundation of…

Methodology · Statistics 2026-03-17 Jinyuan Chang , Chenlong Li , Cheng Yong Tang , Zhengtian Zhu

We describe a series of algorithms that efficiently implement Gaussian model-X knockoffs to control the false discovery rate on large scale feature selection problems. Identifying the knockoff distribution requires solving a large scale…

Machine Learning · Computer Science 2020-06-17 Armin Askari , Quentin Rebjock , Alexandre d'Aspremont , Laurent El Ghaoui

In many scientific fields, researchers are interested in discovering features with substantial effect on the response from a large number of features while controlling the proportion of false discoveries. By incorporating the knockoff…

Methodology · Statistics 2023-02-28 Jiaqi Gu , Guosheng Yin

This paper aims to develop an effective model-free inference procedure for high-dimensional data. We first reformulate the hypothesis testing problem via sufficient dimension reduction framework. With the aid of new reformulation, we…

Methodology · Statistics 2022-05-17 Xu Guo , Runze Li , Zhe Zhang , Changliang Zou