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Testing independence among a number of (ultra) high-dimensional random samples is a fundamental and challenging problem. By arranging $n$ identically distributed $p$-dimensional random vectors into a $p \times n$ data matrix, we investigate…

Statistics Theory · Mathematics 2017-03-28 Xi Chen , Weidong Liu

This paper revisits the following open question in simultaneous testing of multivariate normal means against two-sided alternatives: Can the method of Benjamini and Hochberg (BH, 1995) control the false discovery rate (FDR) without imposing…

Statistics Theory · Mathematics 2023-04-12 Sanat K. Sarkar

Given a multiple testing situation, the null hypotheses that appear to have sufficiently low probabilities of truth may be rejected using a simple, nonparametric method of decision theory. This applies not only to posterior levels of…

Probability · Mathematics 2025-10-20 David R. Bickel

Multiple hypothesis testing problems arise naturally in science. In this paper, we introduce the new Fast Closed Testing (FACT) method for multiple testing, controlling the family-wise error rate. This error rate is state of the art in many…

Methodology · Statistics 2020-01-22 Edgar Dobriban

Stability and reproducibility are essential considerations in various applications of statistical methods. False Discovery Rate (FDR) control methods are able to control false signals in scientific discoveries. However, many FDR control…

Methodology · Statistics 2025-12-22 Jiajun Sun , Zhanrui Cai , Wei Zhong

One fundamental statistical question for research areas such as precision medicine and health disparity is about discovering effect modification of treatment or exposure by observed covariates. We propose a semiparametric framework for…

Methodology · Statistics 2020-08-04 Muxuan Liang , Menggang Yu

Controlling the False Discovery Rate (FDR) in a variable selection procedure is critical for reproducible discoveries, and it has been extensively studied in sparse linear models. However, it remains largely open in scenarios where the…

Methodology · Statistics 2023-11-16 Yang Cao , Xinwei Sun , Yuan Yao

Accurate simulation of complex physical systems enables the development, testing, and certification of control strategies before they are deployed into the real systems. As simulators become more advanced, the analytical tractability of the…

Robotics · Computer Science 2020-05-27 Lucas Barcelos , Rafael Oliveira , Rafael Possas , Lionel Ott , Fabio Ramos

We study the problem of testing for the presence of random effects in mixed models with high-dimensional fixed effects. To this end, we propose a rank-based graph-theoretic approach to test whether a collection of random effects is zero.…

Methodology · Statistics 2025-06-10 Lynna Chu , Yichuan Bai

In high dimensional analysis, effects of explanatory variables on responses sometimes rely on certain exposure variables, such as time or environmental factors. In this paper, to characterize the importance of each predictor, we utilize its…

Methodology · Statistics 2018-04-11 Yeqing Zhou , Jingyuan Liu , Zhihui Hao , Liping Zhu

Many psychologists do not realize that exploratory use of the popular multiway analysis of variance (ANOVA) harbors a multiple comparison problem. In the case of two factors, three separate null hypotheses are subject to test (i.e., two…

In this article, we introduce the concept of model confidence bounds (MCB) for variable selection in the context of nested models. Similarly to the endpoints in the familiar confidence interval for parameter estimation, the MCB identifies…

Methodology · Statistics 2018-07-27 Yang Li , Yuetian Luo , Davide Ferrari , Xiaonan Hu , Yichen Qin

In statistics and machine learning, when we train a fitted model on available data, we typically want to ensure that we are searching within a model class that contains at least one accurate model -- that is, we would like to ensure an…

Statistics Theory · Mathematics 2025-06-06 Manuel M. Müller , Yuetian Luo , Rina Foygel Barber

Recent model-free reinforcement learning algorithms have proposed incorporating learned dynamics models as a source of additional data with the intention of reducing sample complexity. Such methods hold the promise of incorporating imagined…

Machine Learning · Computer Science 2018-03-02 Vladimir Feinberg , Alvin Wan , Ion Stoica , Michael I. Jordan , Joseph E. Gonzalez , Sergey Levine

Addressing the simultaneous identification of contributory variables while controlling the false discovery rate (FDR) in high-dimensional data is a crucial statistical challenge. In this paper, we propose a novel model-free variable…

Methodology · Statistics 2024-04-23 Yixin Han , Xu Guo , Changliang Zou

Estimating the impact of systematic uncertainties in particle physics experiments is challenging, especially since the detector response is unknown analytically in most situations and needs to be estimated through Monte Carlo (MC)…

High Energy Physics - Experiment · Physics 2023-07-28 Leander Fischer , Richard Naab , Alexandra Trettin

We consider the multiple testing of the general regression framework aiming at studying the relationship between a univariate response and a p-dimensional predictor. To test the hypothesis of the effect of each predictor, we construct an…

Methodology · Statistics 2023-06-19 Zhigen Zhao , Xin Xing

The rapid generation of complex, highly skewed, and zero-inflated multi-source count data poses significant challenges for variable selection, particularly in biomedical domains like tumor development and metabolic dysregulation. To address…

Applications · Statistics 2025-11-11 Shan Tang , Shanjun Mao , Shourong Ma , Falong Tan

Although evidence integration to the boundary model has successfully explained a wide range of behavioral and neural data in decision making under uncertainty, how animals learn and optimize the boundary remains unresolved. Here, we propose…

Neural and Evolutionary Computing · Computer Science 2024-08-13 Jamal Esmaily , Rani Moran , Yasser Roudi , Bahador Bahrami

This paper develops a general method of inference for fixed effects models which is (i) automatic, (ii) computationally inexpensive, (iii) tuning parameter-free, and (iv) highly model agnostic. Specifically, we show how to combine a…

Econometrics · Economics 2026-04-23 Ayden Higgins
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