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We present algebraic techniques to analyze state space models in the areas of structural identifiability, observability, and indistinguishability. While the emphasis is on surveying existing algebraic tools for studying ODE systems, we also…

Optimization and Control · Mathematics 2016-09-27 Nicolette Meshkat , Zvi Rosen , Seth Sullivant

This work studies the limitations of uniquely identifying the structure (i.e., topology) of a networked linear system from partial measurements of its nodal dynamics. In general, many networks can be consistent with these measurements; this…

Systems and Control · Electrical Eng. & Systems 2026-03-13 Jaidev Gill , Jing Shuang Li

Detection and identification of nonlinearity is a task of high importance for structural dynamics. Detecting nonlinearity in a structure, which has been designed to operate in its linear region, might indicate the existence of damage.…

Machine Learning · Computer Science 2024-01-08 G. Tsialiamanis , C. R. Farrar

To understand and explain process behaviour we need to be able to see it, and decide its significance, i.e. be able to tell a story about its behaviours. This paper describes a few of the modelling challenges that underlie monitoring and…

Multiagent Systems · Computer Science 2019-07-26 Mark Burgess

Structural monitoring for complex built environments often suffers from mismatch between design, laboratory testing, and actual built parameters. Additionally, real-world structural identification problems encounter many challenges. For…

Machine Learning · Computer Science 2022-08-29 Xuyang Li , Hamed Bolandi , Talal Salem , Nizar Lajnef , Vishnu Naresh Boddeti

Synthetic biology is a recent area of biological engineering, whose aim is to provide cells with novel functionalities. A number of important results regarding the development of control circuits in synthetic biology have been achieved…

Systems and Control · Electrical Eng. & Systems 2024-11-11 Antón Pardo , Sandra Díaz Seoane , Dorin A. Ionescu , Antonis Papachristodoulou , Alejandro F. Villaverde

A joint characterisation of the controllability and observability of a particular kind of discrete system has been developed. The key idea of the procedure can be reduced to a correct choice of the sampling sequence. This freedom, owing to…

Dynamical Systems · Mathematics 2010-06-14 Amparo Fúster-Sabater , J. M. Guillén

Differential balancing theory for nonlinear model reduction relies on differential controllability and observability functions. In this paper, we further investigate them from two different perspectives. First, we establish novel…

Systems and Control · Electrical Eng. & Systems 2025-04-07 Yu Kawano , Bart Besselink , Jacquelien M. A. Scherpen

This paper studies the structural controllability of a class of uncertain switched linear systems, where the parameters of subsystems state matrices are either unknown or zero. The structural controllability is a generalization of the…

Systems and Control · Computer Science 2013-08-27 Xiaomeng Liu , Hai Lin , Ben M. Chen

Observability and controllability are essential concepts to the design of predictive observer models and feedback controllers of networked systems. For example, noncontrollable mathematical models of real systems have subspaces that…

Neurons and Cognition · Quantitative Biology 2018-04-18 Andrew J. Whalen , Sean N. Brennan , Timothy D. Sauer , Steven J. Schiff

A dynamical network, a graph whose nodes are dynamical systems, is usually characterized by a large dimensional space which is not always accesible due to the impossibility of measuring all the variables spanning the state space. Therefore,…

Chaotic Dynamics · Physics 2019-07-25 Irene Sendiña-Nadal , Christophe Letellier

We study the evolution of observables of dynamical systems. For linear systems, we show that observables satisfy a closed differential equation whose minimal order is determined by the dynamical system and observation operator. This yields…

Dynamical Systems · Mathematics 2026-03-24 Xinyu Liu , Dongbin Xiu

A foundational question in the theory of linear compartmental models is how to assess whether a model is structurally identifiable -- that is, whether parameter values can be inferred from noiseless data -- directly from the combinatorics…

Dynamical Systems · Mathematics 2024-02-19 Cashous Bortner , Elizabeth Gross , Nicolette Meshkat , Anne Shiu , Seth Sullivant

Structural identifiability analysis determines whether the parameters of a mechanistic ordinary differential equation (ODE) model can be uniquely recovered from ideal observations and is therefore a fundamental prerequisite for reliable…

Methodology · Statistics 2026-05-20 Abdallah Alsammani

This paper proposes a novel approach for designing functional observers for nonlinear systems, with linear error dynamics and assignable poles. Sufficient conditions for functional observability are first derived, leading to functional…

Systems and Control · Electrical Eng. & Systems 2025-01-03 Costas Kravaris

Structural controllability has been proposed as an analytical framework for making predictions regarding the control of complex networks across myriad disciplines in the physical and life sciences (Liu et al., Nature:473(7346):167-173,…

Physics and Society · Physics 2015-05-28 Noah J. Cowan , Erick J. Chastain , Daril A. Vilhena , James S. Freudenberg , Carl T. Bergstrom

Ordinary differential equation models have become a standard tool for the mechanistic description of biochemical processes. If parameters are inferred from experimental data, such mechanistic models can provide accurate predictions about…

Quantitative Methods · Quantitative Biology 2018-10-12 Fabian Fröhlich , Carolin Loos , Jan Hasenauer

Ordinary differential equations (ODEs) are widely used to model dynamical behavior of systems. It is important to perform identifiability analysis prior to estimating unknown parameters in ODEs (a.k.a. inverse problem), because if a system…

Optimization and Control · Mathematics 2021-03-11 Xing Qiu , Tao Xu , Babak Soltanalizadeh , Hulin Wu

Structural global parameter identifiability indicates whether one can determine a parameter's value from given inputs and outputs in the absence of noise. If a given model has parameters for which there may be infinitely many values, such…

Symbolic Computation · Computer Science 2022-04-05 Ilia Ilmer , Alexey Ovchinnikov , Gleb Pogudin , Pedro Soto

The successful application of epidemic models hinges on our ability to estimate model parameters from limited observations reliably. An often-overlooked step before estimating model parameters consists of ensuring that the model parameters…

Quantitative Methods · Quantitative Biology 2023-09-29 Gerardo Chowell , Sushma Dahal , Yuganthi R. Liyanage , Amna Tariq , Necibe Tuncer