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Related papers: Observability and Structural Identifiability of No…

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A large variety of dynamical systems, such as chemical and biomolecular systems, can be seen as networks of nonlinear entities. Prediction, control, and identification of such nonlinear networks require knowledge of the state of the system.…

Optimization and Control · Mathematics 2018-06-27 Aleksandar Haber , Ferenc Molnar , Adilson E. Motter

The problems of observability and identifiability have been of great interest as previous steps to estimating parameters and initial conditions of dynamical systems to which some known data (observations) are associated. While most works…

Dynamical Systems · Mathematics 2025-06-16 Alicja B Kubik , Benjamin Ivorra , Alain Rapaport , Ángel M Ramos

In this paper, we introduce the concept of observability of targeted state variables for systems that may not be fully observable. For their estimation, we introduce and exemplify a deep filter, which is a neural network specifically…

Systems and Control · Electrical Eng. & Systems 2022-01-13 Wei Kang , Liang Xu , Hong Zhou

We may attempt to encapsulate what we know about a physical system by a model structure, $S$. This collection of related models is defined by parametric relationships between system features; say observables (outputs), unobservable…

Methodology · Statistics 2021-02-16 Jason M. Whyte

Structural identifiability is a property of a differential model with parameters that allows for the parameters to be determined from the model equations in the absence of noise. The method of input-output equations is one method for…

Dynamical Systems · Mathematics 2022-01-28 Alexey Ovchinnikov , Gleb Pogudin , Peter Thompson

Researchers develop models to explain the unknowns. These models typically involve parameters that capture tangible quantities, the estimation of which is desired. Parameter identifiability investigates the recoverability of the unknown…

Optimization and Control · Mathematics 2024-07-01 Anuththara Sarathchandra , Azadeh Aghaeeyan , Pouria Ramazi

Identifiability is a structural property of any ODE model characterized by a set of unknown parameters. It describes the possibility of determining the values of these parameters from fusing the observations of the system inputs and…

Systems and Control · Electrical Eng. & Systems 2024-09-12 Agostino Martinelli

Stochasticity plays a key role in many biological systems, necessitating the calibration of stochastic mathematical models to interpret associated data. For model parameters to be estimated reliably, it is typically the case that they must…

The concept of dynamical compensation has been recently introduced to describe the ability of a biological system to keep its output dynamics unchanged in the face of varying parameters. Here we show that, according to its original…

Quantitative Methods · Quantitative Biology 2018-02-07 Alejandro F. Villaverde , Julio R. Banga

We discuss issues of structural and practical identifiability of partially observed differential equations which are often applied in systems biology. The development of mathematical methods to investigate structural non-identifiability has…

This paper is concerned with a characterization of the observability for a continuous-time hidden Markov model where the state evolves as a general continuous-time Markov process and the observation process is modeled as nonlinear function…

Probability · Mathematics 2020-02-25 Jin W. Kim , Prashant G. Mehta

In this paper, a general framework is proposed for the analysis and characterization of observability and diagnosability of finite state systems. Observability corresponds to the reconstruction of the system's discrete state, while…

Optimization and Control · Mathematics 2016-11-28 Elena De Santis , Maria Domenica Di Benedetto

Identifying latent variables and causal structures from observational data is essential to many real-world applications involving biological data, medical data, and unstructured data such as images and languages. However, this task can be…

Machine Learning · Computer Science 2023-11-01 Lingjing Kong , Biwei Huang , Feng Xie , Eric Xing , Yuejie Chi , Kun Zhang

While hidden class models of various types arise in many statistical applications, it is often difficult to establish the identifiability of their parameters. Focusing on models in which there is some structure of independence of some of…

Statistics Theory · Mathematics 2009-09-01 Elizabeth S. Allman , Catherine Matias , John A. Rhodes

A joint characterisation of the observability and controllability of a particular kind of discrete system has been developed. The key idea of the procedure can be reduced to a correct choice of the sampling sequence. This freedom, owing to…

Discrete Mathematics · Computer Science 2010-06-23 Amparo Fúster-Sabater , J. M. Guillén

In this paper we propose a new observability property for nonautonomous linear control systems in finite dimension: the nonuniform complete observability, which is more general than the uniform complete observability. A dual relationship is…

Optimization and Control · Mathematics 2025-08-14 Ignacio Huerta , Pablo Monzón

The dynamics of systems biological processes are usually modeled by a system of ordinary differential equations (ODEs) with many unknown parameters that need to be inferred from noisy and sparse measurements. Here, we introduce…

Quantitative Methods · Quantitative Biology 2022-02-04 Mitchell Daneker , Zhen Zhang , George Em Karniadakis , Lu Lu

This paper considers the observability of nonlinear systems from a Koopman operator theoretic perspective--and in particular--the effect of symmetry on observability. We first examine an infinite-dimensional linear system (constructed using…

Systems and Control · Computer Science 2020-02-11 Afshin Mesbahi , Jingjing Bu , Mehran Mesbahi

Several concepts on the measure of observability, reachability, and robustness are defined and illustrated for both linear and nonlinear control systems. Defined by using computational dynamic optimization, these concepts are applicable to…

Optimization and Control · Mathematics 2009-07-17 Wei Kang , Liang Xu

We introduce a subclass of Lie symmetries, called parameter-state symmetries, to analyse the local structural identifiability and observability of mechanistic models consisting of state-dependent ODEs with observed outputs. These symmetries…

Dynamical Systems · Mathematics 2026-03-13 Johannes G. Borgqvist , Alexander P. Browning , Fredrik Ohlsson , Ruth E. Baker