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Glaucoma is a chronic eye disease characterized by optic neuropathy, leading to irreversible vision loss. It progresses gradually, often remaining undiagnosed until advanced stages. Early detection is crucial to monitor atrophy and develop…
Purpose: To evaluate Pegasus-OCT, a clinical decision support software for the identification of features of retinal disease from macula OCT scans, across heterogenous populations involving varying patient demographics, device…
Dynamic full-field optical coherence microscopy (d-FF-OCM) is a label-free imaging technique that captures intrinsic subcellular motions to generate functional contrast. This dynamic approach yields images with fluorescence-like contrast,…
Purpose: To determine whether deep learning models can distinguish between breast cancer molecular subtypes based on dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI). Materials and methods: In this institutional review…
Computer-assisted automatic analysis of diabetic retinopathy (DR) is of great importance in reducing the risks of vision loss and even blindness. Ultra-wide optical coherence tomography angiography (UW-OCTA) is a non-invasive and safe…
Clinical cystoscopy, the current standard for bladder cancer diagnosis, suffers from significant reliance on physician expertise, leading to variability and subjectivity in diagnostic outcomes. There is an urgent need for objective,…
Optical coherence tomography (OCT) can provide high-resolution cross-sectional images for analyzing superficial plaques in coronary arteries. Commonly, plaque characterization using intra-coronary OCT images is performed manually by expert…
Serial sectioning Optical Coherence Tomography (sOCT) is a high-throughput, label free microscopic imaging technique that is becoming increasingly popular to study post-mortem neurovasculature. Quantitative analysis of the vasculature…
Given the capacity of Optical Coherence Tomography (OCT) imaging to display symptoms of a wide variety of eye diseases and neurological disorders, the need for OCT image segmentation and the corresponding data interpretation is latterly…
Modern biomedical image analysis using deep learning often encounters the challenge of limited annotated data. To overcome this issue, deep generative models can be employed to synthesize realistic biomedical images. In this regard, we…
Melanoma is considered to be the most aggressive form of skin cancer. Due to the similar shape of malignant and benign cancerous lesions, doctors spend considerably more time when diagnosing these findings. At present, the evaluation of…
Cardiovascular diseases (CVD) are the leading cause of death globally. Non-invasive, cost-effective imaging techniques play a crucial role in early detection and prevention of CVD. Optical coherence tomography (OCT) has gained recognition…
The Internet of Things (IoT) is a concept by which objects find identity and can communicate with each other in a network. One of the applications of the IoT is in the field of medicine, which is called the Internet of Medical Things…
This dissertation relates to the transition of the state of the art of swept source optical coherence tomography (SS-OCT) systems to a new realm in which the image acquisition speed is improved by an order of magnitude. With the aid of a…
Optical Coherence Tomography Angiography (OCTA) is a non-invasive imaging technique that provides high-resolution cross-sectional images of the retina, which are useful for diagnosing and monitoring various retinal diseases. However, manual…
Background: The lack of explanations for the decisions made by algorithms such as deep learning has hampered their acceptance by the clinical community despite highly accurate results on multiple problems. Recently, attribution methods have…
Breast cancer has become one of the most prevalent cancers by which people all over the world are affected and is posed serious threats to human beings, in a particular woman. In order to provide effective treatment or prevention of this…
Background and Aim: Recently, deep learning using convolutional neural network has been used successfully to classify the images of breast cells accurately. However, the accuracy of manual classification of those histopathological images is…
Lung cancer (LC) ranks among the most frequently diagnosed cancers and is one of the most common causes of death for men and women worldwide. Computed Tomography (CT) images are the most preferred diagnosis method because of their low cost…
The ever-growing deep learning technologies are making revolutionary changes for modern life. However, conventional computing architectures are designed to process sequential and digital programs, being extremely burdened with performing…