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In this paper, we study achievable rates of concatenated coding schemes over a deoxyribonucleic acid (DNA) storage channel. Our channel model incorporates the main features of DNA-based data storage. First, information is stored on many,…

Information Theory · Computer Science 2020-05-04 Andreas Lenz , Lorenz Welter , Sven Puchinger

Motivated by mutation processes occurring in in-vivo DNA-storage applications, a channel that mutates stored strings by duplicating substrings as well as substituting symbols is studied. Two models of such a channel are considered: one in…

Information Theory · Computer Science 2020-07-01 Yuanyuan Tang , Yonatan Yehezkeally , Moshe Schwartz , Farzad Farnoud

DNA as a data storage medium has several advantages, including far greater data density compared to electronic media. We propose that schemes for data storage in the DNA of living organisms may benefit from studying the reconstruction…

Information Theory · Computer Science 2019-09-10 Yonatan Yehezkeally , Moshe Schwartz

Storage systems have a strong need for substantially improving their error correction capabilities, especially for long-term storage where the accumulating errors can exceed the decoding threshold of error-correcting codes (ECCs). In this…

Information Theory · Computer Science 2018-11-12 Pulakesh Upadhyaya , Anxiao , Jiang

In the information explosion era, the demand for high-density stable storage technologies is soaring. Multi-dimensional optical storage with femtosecond laser writing offers a potential solution for massive data storage. However, equipment…

Reliability is an important requirement for both communication and storage systems. Due to continuous scale down of technology multiple adjacent bits error probability increases. The data may be corrupted due soft errors. Error correction…

Hardware Architecture · Computer Science 2020-02-19 Sayan Tripathi , Jhilam Jana , Jaydeb Bhaumik

Deep Neural Network (DNN) has achieve great success in solving a wide range of machine learning problems. Recently, they have been deployed in datacenters (potentially for business-critical or industrial applications) and safety-critical…

Hardware Architecture · Computer Science 2025-08-19 Mohsen Raji , Mohammad Zaree , Kimia Soroush

In this paper, we study the problem of storing an archive of versioned data in a reliable and efficient manner in distributed storage systems. We propose a new storage technique called differential erasure coding (DEC) where the differences…

Information Theory · Computer Science 2015-03-19 J. Harshan , Anwitaman Datta , Frédérique Oggier

Locally Decodable Codes (LDCs) are error-correcting codes $C:\Sigma^n\rightarrow \Sigma^m$ with super-fast decoding algorithms. They are important mathematical objects in many areas of theoretical computer science, yet the best…

Information Theory · Computer Science 2022-09-20 Alex Block , Jeremiah Blocki , Kuan Cheng , Elena Grigorescu , Xin Li , Yu Zheng , Minshen Zhu

We provide an overview of current approaches to DNA-based storage system design and accompanying synthesis, sequencing and editing methods. We also introduce and analyze a suite of new constrained coding schemes for both archival and random…

Emerging Technologies · Computer Science 2015-07-08 S. M. Hossein Tabatabaei Yazdi , Han Mao Kiah , Eva Ruiz Garcia , Jian Ma , Huimin Zhao , Olgica Milenkovic

To increase the information capacity of DNA storage, composite DNA letters were introduced. We propose a novel channel model for composite DNA in which composite sequences are decomposed into ordered standard non-composite sequences. The…

Information Theory · Computer Science 2025-10-31 Besart Dollma , Ohad Elishco , Eitan Yaakobi

To equip DNA-based data storage with random-access capabilities, Yazdi et al. (2018) prepended DNA strands with specially chosen address sequences called primers and provided certain design criteria for these primers. We provide explicit…

Information Theory · Computer Science 2019-01-07 Yeow Meng Chee , Han Mao Kiah , Hengjia Wei

Though deep learning has been applied successfully in many scenarios, malicious inputs with human-imperceptible perturbations can make it vulnerable in real applications. This paper proposes an error-correcting neural network (ECNN) that…

Machine Learning · Computer Science 2021-05-10 Yang Song , Qiyu Kang , Wee Peng Tay

This paper studies \emph{linear} and \emph{affine} error-correcting codes for correcting synchronization errors such as insertions and deletions. We call such codes linear/affine insdel codes. Linear codes that can correct even a single…

Information Theory · Computer Science 2022-07-22 Kuan Cheng , Venkatesan Guruswami , Bernhard Haeupler , Xin Li

DNA has emerged as a promising alternative for long-term data storage due to its high capacity, durability, and low-energy potential. However, storing data in DNA presents several challenges. First, it requires complex and costly…

Other Quantitative Biology · Quantitative Biology 2025-11-20 Sara Al Sayyed , Aline Roumy , Thomas Maugey

As the global need for large-scale data storage is rising exponentially, existing storage technologies are approaching their theoretical and functional limits in terms of density and energy consumption, making DNA based storage a potential…

Emerging Technologies · Computer Science 2021-10-12 Yotam Nahum , Eyar Ben-Tolila , Leon Anavy

Error Detection and Correction Codes (ECCs) are often used in digital designs to protect data integrity. Especially in safety-critical systems such as automotive electronics, ECCs are widely used and the verification of such complex logic…

Artificial Intelligence · Computer Science 2024-04-30 Aman Kumar

In this paper, we propose a novel iterative encoding algorithm for DNA storage to satisfy both the GC balance and run-length constraints using a greedy algorithm. DNA strands with run-length more than three and the GC balance ratio far from…

Information Theory · Computer Science 2023-01-04 Seong-Joon Park , Yongwoo Lee , Jong-Seon No

This paper extends the foundational work of Dollma \emph{et al}. on codes for ordered composite DNA sequences. We consider the general setting with an alphabet of size $q$ and a resolution parameter $k$, moving beyond the binary ($q=2$)…

Information Theory · Computer Science 2026-02-19 Zuo Ye , Yuling Li , Zhaojun Lan , Gennian Ge

Composite DNA is a recent novel method to increase the information capacity of DNA-based data storage above the theoretical limit of 2 bits/symbol. In this method, every composite symbol does not store a single DNA nucleotide but a mixture…

Information Theory · Computer Science 2025-01-22 Tuan Thanh Nguyen , Chen Wang , Kui Cai , Yiwei Zhang , Zohar Yakhini
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