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We previously developed a system for projection-based magnetic particle imaging (MPI) with a field-free-line (FFL) encoding scheme. In the projection-based MPI, projection data are given by the convolution between the system function in the…

Medical Physics · Physics 2019-07-04 Kenya Murase

Magnetic nanoparticles (MNPs) play an important role in biomedical applications including imaging modalities such as MRI and magnetic particle imaging (MPI). The latter one exploits the non-linear magnetization response of a large ensemble…

Mesoscale and Nanoscale Physics · Physics 2021-10-27 Hannes Albers , Tobias Knopp , Martin Möddel , Marija Boberg , Tobias Kluth

Magnetic Particle Imaging (MPI) is a tomographic imaging technique for determining the spatial distribution of superparamagnetic nanoparticles. Current MPI systems are capable of imaging iron masses over a wide dynamic range of more than…

Magnetic Particle Imaging (MPI) is a promising tracer-based, functional medical imaging technique which measures the non-linear magnetization response of magnetic nanoparticles to a dynamic magnetic field. For image reconstruction, system…

Image and Video Processing · Electrical Eng. & Systems 2021-08-26 Christina Brandt , Christiane Schmidt

Magnetic particle imaging (MPI) is a relatively new imaging modality. The nonlinear magnetization behavior of nanoparticles in an applied magnetic field is employed to reconstruct an image of the concentration of nanoparticles. Finding a…

Applied Physics · Physics 2018-07-04 Tobias Kluth

Magnetic particle imaging (MPI) is a non-invasive, non-ionizing imaging technique for the visualization and quantification of magnetic nanoparticles (MNPs). The technique is especially suitable for cell imaging as it offers zero background…

Magnetic Particle Imaging (MPI) has been successfully used to visualize the distribution of superparamagnetic nanoparticles within 3D volumes with high sensitivity in real time. Since the magnetic field topology of MPI scanners is well…

Magnetic Particle Imaging (MPI) is a recent imaging modality where superparamagnetic nanoparticles are employed as tracers. The reconstruction task is to obtain the spatial particle distribution from a voltage signal induced by the…

Numerical Analysis · Mathematics 2025-08-11 Thomas März , Vladyslav Gapyak , Andreas Weinmann

In Magnetic Particle Imaging (MPI), the distribution of magnetic nanoparticles (MNPs) is imaged by moving a field free point (FFP) in space. All MNPs in close vicinity of the FFP contribute to the signal induced on the receive coil. The…

Signal Processing · Electrical Eng. & Systems 2021-12-02 Atakan Topcu , Asli Alpman , Mustafa Utkur , Emine Ulku Saritas

Magnetic particle imaging (MPI) is an imaging modality exploiting the nonlinear magnetization behavior of (super-)paramagnetic nanoparticles to obtain a space- and often also time-dependent concentration of a tracer consisting of these…

Image and Video Processing · Electrical Eng. & Systems 2020-07-06 Sören Dittmer , Tobias Kluth , Mads Thorstein Roar Henriksen , Peter Maass

Visualization of the in vivo spatial distribution of superparamagnetic iron oxide nanoparticles (SPIONs) is crucial to biomedicine. Magnetic particle imaging (MPI) is one of the most promising approaches for direct measurements of the SPION…

Medical Physics · Physics 2022-07-13 Klaas-Julian Janssen , Meinhard Schilling , Frank Ludwig , Jing Zhong

Magnetic Particle Imaging (MPI) is a novel imaging modality with important applications such as angiography, stem cell tracking, and cancer imaging. Recently, there have been efforts to increase the functionality of MPI via multi-color…

Medical Physics · Physics 2017-05-23 Yavuz Muslu , Mustafa Utkur , Omer Burak Demirel , Emine Ulku Saritas

Magnetic particle imaging (MPI) is a promising new in-vivo medical imaging modality in which distributions of super-paramagnetic nanoparticles are tracked based on their response in an applied magnetic field. In this paper we provide a…

Magnetic particle imaging (MPI) is a tracer-based medical imaging modality that enables quantification and spatial mapping of magnetic nanoparticle (MNP) distribution. The magnetization response of MNPs depends on experimental conditions…

Signal Processing · Electrical Eng. & Systems 2025-09-03 Asli Alpman , Mustafa Utkur , Emine Ulku Saritas

Magnetic Particle Imaging (MPI) is a promising imaging modality that tracks magnetic nanoparticles (MNPs) to generate real time, high-resolution images. However, achieving an optimal balance between strong signal strength and sharp image…

Medical Physics · Physics 2025-12-18 Abuobaida M. khair , Wenjing Jiang , Moritz Wildgruber , Wenjun Xi , Xiaopeng Ma

The purpose of this study was to present image reconstruction methods for magnetic particle imaging (MPI) with a field-free-line (FFL) encoding scheme and to propose the use of the maximum likelihood-expectation maximization (ML-EM)…

Medical Physics · Physics 2016-06-13 Kenya Murase

Magnetic particle spectroscopy (MPS) is one of the most versatile methods to characterize the magnetic properties of magnetic nanoparticles (MNPs). The excitation magnetic field is one of the most crucial factors that affects the MPS signal…

Applied Physics · Physics 2023-04-25 Shaoqi Sun , Shijie Sun , Lijun Xu , Jing Zhong

We report on our progress in the development of an atomic magnetometer (AM) based low-frequency magnetic particle imaging (MPI) scanner, expected to be free from Specific Absorption Rate (SAR) and Peripheral Nerve Stimulation (PNS)…

Instrumentation and Detectors · Physics 2017-01-16 Simone Colombo , Victor Lebedev , Alexey Tonyushkin , Zoran D. Grujic , Vladimir Dolgovskiy , Antoine Weis

Magnetic particle imaging (MPI) is an in-vivo imaging method to detect magnetic nanoparticles for blood vessel imaging and molecular target imaging. Compared with conventional molecular imaging devices (such as nuclear medicine imaging PET…

Medical Physics · Physics 2024-04-26 Guang Jia , Zhongwei Bian , Tianshu Li , Shi Bai , Chenxing Hu , Lixuan Zhao , Peng Gao , Tanping Li , Hui Hui , Jie Tian

The image reconstruction problem of the tomographic imaging technique magnetic particle imaging (MPI) requires the solution of a linear inverse problem. One prerequisite for this task is that the imaging operator that describes the mapping…

Computational Physics · Physics 2019-07-12 Tobias Kluth , Patryk Szwargulski , Tobias Knopp
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