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The concept of personalised medicine in cancer therapy is becoming increasingly important. There already exist drugs administered specifically for patients with tumours presenting well-defined mutations. However, the field is still in its…

Biomolecules · Quantitative Biology 2024-08-26 Abbi Abdel-Rehim , Oghenejokpeme Orhobor , Gareth Griffiths , Larisa Soldatova , Ross D. King

Interpreting large volumes of high-dimensional, unlabeled data in a manner that is comprehensible to humans remains a significant challenge across various domains. In unsupervised healthcare data analysis, interpreting clustered data can…

Machine Learning · Computer Science 2025-06-17 Shehroz S. Khan , Ali Abedi , Charlene H. Chu

Clinical case reports encode temporal patient trajectories that are often underexploited by traditional machine learning methods relying on structured data. In this work, we introduce the forecasting problem from textual time series, where…

Computation and Language · Computer Science 2025-12-30 Shahriar Noroozizadeh , Sayantan Kumar , Jeremy C. Weiss

Many fields collect large-scale temporal data through repeated measurements (trials), where each trial is labeled with a set of metadata variables spanning several categories. For example, a trial in a neuroscience study may be linked to a…

Machine Learning · Computer Science 2026-02-05 Noga Mudrik , Yuxi Chen , Gal Mishne , Adam S. Charles

Progress notes are among the most clinically meaningful artifacts in an Electronic Health Record (EHR), offering temporally grounded insights into a patient's evolving condition, treatments, and care decisions. Despite their importance,…

Computation and Language · Computer Science 2025-07-21 Garapati Keerthana , Manik Gupta

We propose a novel neural method to extract drug-drug interactions (DDIs) from texts using external drug molecular structure information. We encode textual drug pairs with convolutional neural networks and their molecular pairs with graph…

Computation and Language · Computer Science 2018-05-16 Masaki Asada , Makoto Miwa , Yutaka Sasaki

Motivation: Patient-generated text contains critical information about patients' lived experiences, social circumstances, and engagement in care, including factors that strongly influence adherence, care coordination, and health equity.…

Computation and Language · Computer Science 2026-03-09 Samah Fodeh , Linhai Ma , Ganesh Puthiaraju , Srivani Talakokkul , Afshan Khan , Ashley Hagaman , Sarah Lowe , Aimee Roundtree

Prognoses of Traumatic Brain Injury (TBI) outcomes are neither easily nor accurately determined from clinical indicators. This is due in part to the heterogeneity of damage inflicted to the brain, ultimately resulting in diverse and complex…

We study the problem of learning individualized dose intervals using observational data. There are very few previous works for policy learning with continuous treatment, and all of them focused on recommending an optimal dose rather than an…

Methodology · Statistics 2022-02-25 Guanhua Chen , Xiaomao Li , Menggang Yu

Text recognition methods are gaining rapid development. Some advanced techniques, e.g., powerful modules, language models, and un- and semi-supervised learning schemes, consecutively push the performance on public benchmarks forward.…

Computer Vision and Pattern Recognition · Computer Science 2024-01-01 Ziyin Zhang , Ning Lu , Minghui Liao , Yongshuai Huang , Cheng Li , Min Wang , Wei Peng

Estimating treatment effects plays a crucial role in causal inference, having many real-world applications like policy analysis and decision making. Nevertheless, estimating treatment effects in the longitudinal setting in the presence of…

Machine Learning · Computer Science 2023-02-22 Defu Cao , James Enouen , Yan Liu

Clinical notes are an efficient way to record patient information but are notoriously hard to decipher for non-experts. Automatically simplifying medical text can empower patients with valuable information about their health, while saving…

Clinicians may rely on medical coding systems such as International Classification of Diseases (ICD) to identify patients with diseases from Electronic Health Records (EHRs). However, due to the lack of detail and specificity as well as a…

Computation and Language · Computer Science 2022-05-19 Jingqing Zhang , Atri Sharma , Luis Bolanos , Tong Li , Ashwani Tanwar , Vibhor Gupta , Yike Guo

Unstructured information comprises a valuable source of data in clinical records. For text mining in clinical records, concept extraction is the first step in finding assertions and relationships. This study presents a system developed for…

Information Retrieval · Computer Science 2010-12-09 Ning Kang , Rogier Barendse , Zubair Afzal , Bharat Singh , Martijn J. Schuemie , Erik M. van Mulligen , Jan A. Kors

Deep learning has achieved spectacular performance in image and speech recognition and synthesis. It outperforms other machine learning algorithms in problems where large amounts of data are available. In the area of measurement technology,…

Quantitative Methods · Quantitative Biology 2019-08-20 Yueqin Li , Ata Mahjoubfar , Claire Lifan Chen , Kayvan Reza Niazi , Li Pei , Bahram Jalali

Clinical diagnosis of the eye is performed over multifarious data modalities including scalar clinical labels, vectorized biomarkers, two-dimensional fundus images, and three-dimensional Optical Coherence Tomography (OCT) scans. Clinical…

Image and Video Processing · Electrical Eng. & Systems 2022-09-23 Mohit Prabhushankar , Kiran Kokilepersaud , Yash-yee Logan , Stephanie Trejo Corona , Ghassan AlRegib , Charles Wykoff

Clinical Text Notes (CTNs) contain physicians' reasoning process, written in an unstructured free text format, as they examine and interview patients. In recent years, several studies have been published that provide evidence for the…

Computation and Language · Computer Science 2022-08-19 Hlynur D. Hlynsson , Steindór Ellertsson , Jón F. Daðason , Emil L. Sigurdsson , Hrafn Loftsson

Cancer subtyping plays a crucial role in informing prognosis and guiding personalized treatment strategies. However, conventional subtyping approaches often rely on static, biopsy-derived scores that hardly capture the biological…

Methodology · Statistics 2026-03-12 Lara Cavinato , Marco Rocchi , Luca Viganò , Francesca Ieva

Medication errors most commonly occur at the ordering or prescribing stage, potentially leading to medical complications and poor health outcomes. While it is possible to catch these errors using different techniques; the focus of this work…

Computation and Language · Computer Science 2022-01-11 Yu Jiang , Christian Poellabauer

Continuity of care is crucial to ensuring positive health outcomes for patients discharged from an inpatient hospital setting, and improved information sharing can help. To share information, caregivers write discharge notes containing…

Computation and Language · Computer Science 2021-06-07 James Mullenbach , Yada Pruksachatkun , Sean Adler , Jennifer Seale , Jordan Swartz , T. Greg McKelvey , Hui Dai , Yi Yang , David Sontag