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In the United States, 25% or greater than 200 billion dollars of hospital spending accounts for administrative costs that involve services for medical coding and billing. With the increasing number of patient records, manual assignment of…

Computation and Language · Computer Science 2020-03-18 A. K. Bhavani Singh , Mounika Guntu , Ananth Reddy Bhimireddy , Judy W. Gichoya , Saptarshi Purkayastha

Accurate and interpretable mortality risk prediction in intensive care units (ICUs) remains a critical challenge due to the irregular temporal structure of electronic health records (EHRs), the complexity of longitudinal disease…

Machine Learning · Computer Science 2026-03-10 Zahra Jafari , Azadeh Zamanifar , Amirfarhad Farhadi

Clinician notes are a rich source of patient information but often contain inconsistencies due to varied writing styles, colloquialisms, abbreviations, medical jargon, grammatical errors, and non-standard formatting. These inconsistencies…

Computation and Language · Computer Science 2025-01-03 Daniel B. Hier , Michael D. Carrithers , Thanh Son Do , Tayo Obafemi-Ajayi

In this research, we present our work participation for the DrugProt task of BioCreative VII challenge. Drug-target interactions (DTIs) are critical for drug discovery and repurposing, which are often manually extracted from the…

Computation and Language · Computer Science 2021-11-09 Jehad Aldahdooh , Ziaurrehman Tanoli , Jing Tang

The clinical notes are usually typed into the system by physicians. They are typically required to be marked by standard medical codes, and each code represents a diagnosis or medical treatment procedure. Annotating these notes is time…

Machine Learning · Computer Science 2023-05-10 Guodong Liu

Electronic Healthcare records contain large volumes of unstructured data in different forms. Free text constitutes a large portion of such data, yet this source of richly detailed information often remains under-used in practice because of…

Computation and Language · Computer Science 2019-10-17 M. Tarik Altuncu , Erik Mayer , Sophia N. Yaliraki , Mauricio Barahona

Non-adherence to medications is a critical concern since nearly half of patients with chronic illnesses do not follow their prescribed medication regimens, leading to increased mortality, costs, and preventable human distress. Amongst stage…

Machine Learning · Computer Science 2025-04-22 Navreet Kaur , Manuel Gonzales , Cristian Garcia Alcaraz , Jiaqi Gong , Kristen J. Wells , Laura E. Barnes

Medication adherence is a problem of widespread concern in clinical care. Poor adherence is a particular problem for patients with chronic diseases requiring long-term medication because poor adherence can result in less successful…

Methodology · Statistics 2021-04-26 Kristen B. Hunter , Mark E. Glickman , Luis F. Campos

Estimating counterfactual outcomes over time has the potential to unlock personalized healthcare by assisting decision-makers to answer ''what-iF'' questions. Existing causal inference approaches typically consider regular, discrete-time…

Machine Learning · Computer Science 2022-06-17 Nabeel Seedat , Fergus Imrie , Alexis Bellot , Zhaozhi Qian , Mihaela van der Schaar

Recent advances in transformer architectures have revolutionised natural language processing, but their application to healthcare domains presents unique challenges. Patient timelines are characterised by irregular sampling, variable…

Computation and Language · Computer Science 2025-05-26 Linglong Qian , Zina Ibrahim

Oncology dose-finding trials are shifting from identifying the maximum tolerated dose (MTD) to determining the optimal biological dose (OBD), driven by the need for efficient methods that consider both toxicity and efficacy. This is…

Methodology · Statistics 2025-04-01 Hao Sun , Jieqi Tu , Revathi Ananthakrishnan , Eunhee Kim

Treatment of cancer involves heterogeneous, complex care pathways. The relationship between these longitudinal trajectories, baseline mental health, and prognostic outcomes remains poorly understood. We introduce an interpretable…

The Clinical E-Science Framework (CLEF) project was used to extract important information from medical texts by building a system for the purpose of clinical research, evidence-based healthcare and genotype-meets-phenotype informatics. The…

Information Retrieval · Computer Science 2013-06-24 Wafaa Tawfik Abdel-moneim , Mohamed Hashem Abdel-Aziz , Mohamed Monier Hassan

Clinical notes contain an extensive record of a patient's health status, such as smoking status or the presence of heart conditions. However, this detail is not replicated within the structured data of electronic health systems.…

Computation and Language · Computer Science 2020-09-18 Andriy Mulyar , Elliot Schumacher , Masoud Rouhizadeh , Mark Dredze

Individualized treatment rules (ITRs) for treatment recommendation is an important topic for precision medicine as not all beneficial treatments work well for all individuals. Interpretability is a desirable property of ITRs, as it helps…

Methodology · Statistics 2023-11-06 Jacob M. Maronge , Jared D. Huling , Guanhua Chen

Annotating cancerous regions in whole-slide images (WSIs) of pathology samples plays a critical role in clinical diagnosis, biomedical research, and machine learning algorithms development. However, generating exhaustive and accurate…

Computer Vision and Pattern Recognition · Computer Science 2022-06-09 Zhenzhen Wang , Carla Saoud , Sintawat Wangsiricharoen , Aaron W. James , Aleksander S. Popel , Jeremias Sulam

Different aspects of a clinical sample can be revealed by multiple types of omics data. Integrated analysis of multi-omics data provides a comprehensive view of patients, which has the potential to facilitate more accurate clinical decision…

Machine Learning · Computer Science 2020-02-11 Xiaoyu Zhang , Jingqing Zhang , Kai Sun , Xian Yang , Chengliang Dai , Yike Guo

Electronic health records capture patient information using structured controlled vocabularies and unstructured narrative text. While structured data typically encodes lab values, encounters and medication lists, unstructured data captures…

Computers and Society · Computer Science 2015-02-17 Preethi Raghavan , James L. Chen , Eric Fosler-Lussier , Albert M. Lai

This research addresses the issue of missing structured data in dental records by extracting diagnostic information from unstructured text. The updated periodontology classification system's complexity has increased incomplete or missing…

Computation and Language · Computer Science 2025-06-04 Yao-Shun Chuang , Chun-Teh Lee , Oluwabunmi Tokede , Guo-Hao Lin , Ryan Brandon , Trung Duong Tran , Xiaoqian Jiang , Muhammad F. Walji

Electronic Health Records (EHRs) provide vital contextual information to radiologists and other physicians when making a diagnosis. Unfortunately, because a given patient's record may contain hundreds of notes and reports, identifying…