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Early diagnosis of Alzheimer's Disease (AD) faces multiple data-related challenges, including high variability in patient data, limited access to specialized diagnostic tests, and overreliance on single-type indicators. These challenges are…
Alzheimers disease is a fatal progressive brain disorder that worsens with time. It is high time we have inexpensive and quick clinical diagnostic techniques for early detection and care. In previous studies, various Machine Learning…
Based on official estimates, 50 million people worldwide are affected by dementia, and this number increases by 10 million new patients every year. Without a cure, clinical prognostication and early intervention represent the most effective…
Alzheimer's disease is the most common neurodegenerative disease. The aim of this study is to infer structural changes in brain connectivity resulting from disease progression using cortical thickness measurements from a cohort of…
Existing research has shown the potential of classifying Alzheimers Disease (AD) from eye-tracking (ET) data with classifiers that rely on task-specific engineered features. In this paper, we investigate whether we can improve on existing…
People suffering from Alzheimer's disease (AD) and their caregivers seek different approaches to cope with memory loss. Although AD patients want to live independently, they often need help from caregivers. In this situation, caregivers may…
Alzheimer's Disease (AD) is a progressive neurodegenerative disease and the leading cause of dementia. Early diagnosis is critical for patients to benefit from potential intervention and treatment. The retina has been hypothesized as a…
Dementia is a neurodegenerative disease that causes gradual cognitive impairment, which is very common in the world and undergoes a lot of research every year to prevent and cure it. It severely impacts the patient's ability to remember…
Alzheimer's disease is a progressive form of dementia that results in problems with memory, thinking, and behavior. It often starts with abnormal aggregation and deposition of beta amyloid and tau, followed by neuronal damage such as…
Alzheimer's disease (AD) is the most common form of dementia, which causes problems with memory, thinking and behavior. Growing evidence has shown that the brain connectivity network experiences alterations for such a complex disease.…
The average life expectancy is increasing globally due to advancements in medical technology, preventive health care, and a growing emphasis on gerontological health. Therefore, developing technologies that detect and track aging-associated…
Alzheimer's disease and Frontotemporal dementia are common forms of neurodegenerative dementia. Behavioral alterations and cognitive impairments are found in the clinical courses of both diseases and their differential diagnosis is…
The incidence of Alzheimer's disease (AD) and other forms of dementia is increasing in most western countries. For a precise and early diagnosis, several examination modalities exist, among them single-photon emission computed tomography…
Alzheimer's Disease Analysis Model (ADAM) is a multi-agent reasoning large language model (LLM) framework designed to integrate and analyze multimodal data, including microbiome profiles, clinical datasets, and external knowledge bases, to…
Aging associated brain decline often result in some kind of dementia. Even when this is a complex brain disorder a physical model can be used in order to describe its general behavior. This model is based in first principles. A…
The rapid emergence of highly adaptable and reusable artificial intelligence (AI) models is set to revolutionize the medical field, particularly in the diagnosis and management of Parkinson's disease (PD). Currently, there are no effective…
Dementia is a mental illness that people live with all across the world. No one is immune. Nothing can predict its onset. The true story of dementia remains unknown globally, partly due to the denial of dementia symptoms and partly due to…
We present a probabilistic programmed deep kernel learning approach to personalized, predictive modeling of neurodegenerative diseases. Our analysis considers a spectrum of neural and symbolic machine learning approaches, which we assess…
Early diagnosis of dementia, particularly in the prodromal stage (i.e., mild cognitive impairment, or MCI), has become a research and clinical priority but remains challenging. Automated analysis of the drawing process has been studied as a…
With the global population aging rapidly, Alzheimer's disease (AD) is particularly prominent in older adults, which has an insidious onset and leads to a gradual, irreversible deterioration in cognitive domains (memory, communication,…