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Related papers: A solid approach to biopharmaceutical stabilisatio…

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The stabilization of macromolecules is fundamental to developing biological formulations, such as vaccines and protein therapeutics. In this study, we employ coarse grained polymer models to investigate the impact of four sugars:…

Soft Condensed Matter · Physics 2025-11-26 Praveen Muralikrishnan , Jonathan W. P. Zajac , Caryn L. Heldt , Sarah L. Perry , Sapna Sarupria

By applying a slow curing process, we show that biomolecules can be incorporated via a simple process as liquid stable phases inside a polydimethylsiloxane (PDMS) matrix. The process is carried out under mild conditions with regards to…

Exploring new topological materials with large topological nontrivial bandgaps and simple composition is attractive for both theoretical investigation and experimental realization. Recently alpha tin ({\alpha}-Sn) has been predicted to be…

Materials Science · Physics 2019-12-10 Huanhuan Song , Jinshan Yao , Yuanfeng Ding , Yu Gu , Yu Deng , Ming-Hui Lu , Hong Lu , Yan-Feng Chen

This paper investigates the behaviour of colloidal suspensions of alumina particles during directional solidification, by in situ high-resolution observations using X-ray radiography and tomography. This second part is focussed on the…

Titanium silicide is a key contact material in advanced three-dimensional semiconductor device architectures. Here, we examine the formation of ultrathin Ti-silicide on Si(100) using a combination of non-destructive in-situ and ex-situ ion…

Controlled formation of porous silicon has been of primary importance for numerous landmark applications such as light emitting sources, sensors, actuators, drug delivery systems, and energy storage applications. Frequently explored methods…

The $\beta$-relaxation associated with the sub-glass transition temperature ($T_{\text{g},\beta}$) is attributed to fast, localised molecular motions which can occur below the primary glass transition temperature ($T_{g\alpha}$). Despite…

Biological Physics · Physics 2019-11-06 Maarten Batens , Talia A. Shmool , Jan Massant , J. Axel Zeitler , Guy Van den Mooter

We report here a new entropic mechanism of protein thermostability due to residual dynamics of rotamer isomerization in native state. All-atom simulations show that Lysines have much greater number of accessible rotamers than Arginines in…

Biomolecules · Quantitative Biology 2015-06-26 Igor N. Berezovsky , William W. Chen , Paul J. Choi , Eugene I. Shakhnovich

Protein crystal production is a major bottleneck for the structural characterisation of proteins. To advance beyond large-scale screening, rational strategies for protein crystallization are crucial. Understanding how chemical anisotropy…

Biomolecules · Quantitative Biology 2022-05-03 Amir R. Khan , Susan James , Michelle K. Quinn , Irem Altan , Patrick Charbonneau , Jennifer J. McManus

Solid phase epitaxy is a crystallization technique used to produce high quality thin films. Lateral solid phase epitaxy furthermore enables the realization of non-planar structures, which are interesting, e.g., in the field of spintronics.…

Pulsed laser deposition, a non-equilibrium thin-film growth technique, was used to stabilize metastable tetragonal iron sulfide (FeS), the bulk state of which is known as a superconductor with a critical temperature of 4 K. Comprehensive…

Materials Science · Physics 2019-03-22 Kota Hanzawa , Masato Sasase , Hidenori Hiramatsu , Hideo Hosono

The binary alloy of titanium-tungsten (TiW) is an established diffusion barrier in high-power semiconductor devices, owing to its ability to suppress the diffusion of copper from the metallisation scheme into the surrounding silicon…

The design of antibacterial-releasing coatings or wrapping materials with controlled drug release capability is a promising strategy to minimise risks of infection and medical device failure in vivo. Collagen fibres have been employed as…

Biomolecules · Quantitative Biology 2021-01-06 M. Tarik Arafat , Giuseppe Tronci , David J. Wood , Stephen J. Russell

Ultrafast lasers create extreme, non-equilibrium thermodynamic conditions that can transiently reach pressures and temperatures comparable to interior core of the earth. Here we show that femtosecond excitation of amorphous silica-hafnia…

Ultracold molecules are becoming an increasingly important technology for quantum simulation, computation, and sensing, but their state preparation in large, low-entropy arrays remains a key challenge. We propose to deterministically load…

Quantum Physics · Physics 2026-03-03 Tijs Karman , Sebastian Will , Zoe Yan

We present confocal microscopy studies of novel particle-stabilized emulsions. The novelty arises because the immiscible fluids have an accessible upper critical solution temperature. The emulsions have been created by beginning with…

Soft Condensed Matter · Physics 2009-11-11 P. S. Clegg , E. M. Herzig , A. B. Schofield , T. S. Horozov , B. P. Binks , M. E. Cates , W. C. K. Poon

Ice-templating is a well-established processing route for porous ceramics. Because of the structure/properties relationships, it is essential to better understand and control the solidification microstructures. Ice-templating is based on…

Soft Condensed Matter · Physics 2017-12-22 Dmytro Dedovets , Sylvain Deville

Disorder induced phase slip (PS) events appearing in the current voltage characteristics (IVCs) are reported for two-dimensional TiN thin films produced by a robust substrate mediated nitridation technique. Here, high temperature annealing…

Superconductivity · Physics 2021-10-25 Sachin Yadav , Vinay Kaushik , M. P. Saravanan , R. P. Aloysius , V. Ganesan , Sangeeta Sahoo

The phenomenon of quantum entanglement marks one of the furthest departures from classical physics and is indispensable for quantum information processing. Despite its fundamental importance, the distribution of entanglement over long…

Quantum Physics · Physics 2021-07-27 Sebastian Ecker , Philipp Sohr , Lukas Bulla , Marcus Huber , Martin Bohmann , Rupert Ursin

With the advances in miniaturization, understanding and controlling properties of significant technological systems like silicon in nano regime assumes considerable importance. It turns out that small silicon clusters in the size range of…

Mesoscale and Nanoscale Physics · Physics 2009-11-11 Shahab Zorriasatein , Kavita Joshi , D. G. Kanhere