By applying a slow curing process, we show that biomolecules can be incorporated via a simple process as liquid stable phases inside a polydimethylsiloxane (PDMS) matrix. The process is carried out under mild conditions with regards to temperature, pH and relative humidity, and is thus suitable for application to biological entities. Fluorescence and enzymatic activity measurements, show that the biochemical properties of the proteins and enzyme tested are preserved, without loss due to adsorption at the liquid-polymer interface. Protected from external stimuli by the PDMS matrix, these soft liquid composite materials are new tools of interest for robotics, microfluidics, diagnostics and chemical microreactors.
@article{arxiv.1907.09710,
title = {Complete inclusion of bioactive molecules and particles in polydime-thylsiloxane: a straightforward process under mild conditions},
author = {Greta Faccio and Alice Cont and Erik Mailand and Elaheh Zare-Eelanjegh and Riccardo Innocenti Malini and Katharina Maniura-Weber and René Michel Rossi and Fabrizio Spano},
journal= {arXiv preprint arXiv:1907.09710},
year = {2019}
}