English
Related papers

Related papers: A solid approach to biopharmaceutical stabilisatio…

200 papers

The silicification of DNA origami structures increases their mechanical and thermal stability and provides chemical protection. So far, it is unclear how silicification affects the internal structure of the DNA origami and whether the whole…

Soft Condensed Matter · Physics 2022-10-12 Martina F. Ober , Anna Baptist , Lea Wassermann , Amelie Heuer-Jungemann , Bert Nickel

Lyophilization (aka freeze drying) is a typical process in pharmaceutical manufacturing used for improving the stability of various drug products, including its recent applications to mRNA vaccines. While extensive efforts have been…

Computational Engineering, Finance, and Science · Computer Science 2025-12-03 Prakitr Srisuma , Gang Chen , Richard D. Braatz

We report that protein confinement within nanoscopic vesicular compartments corresponds to a liquid-liquid phase transition with the protein/water within vesicle lumen interacting very differently than in bulk. We show this effect leads to…

We propose a protocol by which entanglement can be extracted repeatedly from a quantum field. In analogy with prior work on entanglement harvesting, we call this protocol entanglement farming. It consists of successively sending pairs of…

Quantum Physics · Physics 2013-11-15 Eduardo Martin-Martinez , Eric G. Brown , William Donnelly , Achim Kempf

Microfabrication using nano- to micron-sized building blocks holds great potential for applications in next-generation electronics, optoelectronics, and advanced materials. However, traditional methods like chemical vapor deposition and…

Colloidosomes provide a possibility to encapsulate oily substances in water in the form of core-in-shell structures. In this study, we produced microcapsules with shell from colloidal particles, where the interparticle openings are blocked…

Tuberculosis (TB) is one of the deadliest diseases worldwide, with 1,5 million fatalities every year along with potential devastating effects on society, families and individuals. To address this alarming burden, vaccines can play a…

Thermodynamic multi-component solution solidification approach to liquid-to-glass transition is proposed and actual mechanisms underlying vitrification, other than viscous slowdown, are identified. Due to polydisperse aggregation in liquid…

Materials Science · Physics 2022-09-14 Vladimir Belostotsky

Vanadium silicide (V$_3$Si) is a promising superconductor for integration with silicon-based electronics, however the interfacial growth kinetics have a strong influence on the resulting superconducting properties and are not yet fully…

Recent demonstrations of extraordinary stabilization of proteins in mobile protic [1] and aprotic [2] ionic liquid solutions at ambient temperatures have raised hopes of new biopreservation and drug transportation technologies. Here we…

Biological Physics · Physics 2007-10-23 Nolene Byrne , Jean-Philippe Belieres , C. Austen Angell

Inorganic-organic interfaces are important for enhancing the power conversion efficiency of silicon-based solar cells through singlet exciton fission (SF). We elucidated the structure of the first monolayers of tetracene (Tc), a SF…

Protein-inorganic hybrid nanoflowers (HNFs) possess unique properties in promoting surface reaction and have attracted wide-spread attention as a newly developed nanomaterial. However, the availability of protein sources has up to now been…

Soft Condensed Matter · Physics 2022-10-27 Penghui Shen , Mouming Zhao , Jasper Landman , Feibai Zhou

Dense and mesoporous 4% mol Yttria-stabilized zirconia thin films were deposited on amorphous silica substrates. The effects of the temperature on the mesostructure were analyzed, by applying different thermal treatments to the samples…

Emulsions are a central component of many modern formulations in food, pharmaceuticals, agrichemicals and personal care products. The droplets in these formulations are limited to being spherical as a consequence of the interfacial tension…

Soft Condensed Matter · Physics 2017-05-15 Keith M. Bromley , Cait E. MacPhee

Entanglement distillation, the process of converting weakly entangled states into maximally entangled ones using Local Operations and Classical Communication (LOCC), is pivotal for robust entanglement-assisted quantum information processing…

Quantum Physics · Physics 2025-12-17 Christopher Popp , Tobias C. Sutter , Beatrix C. Hiesmayr

Existence of strongly bound water molecules on silicate surfaces, above the desorption temperature of water ice, has been first predicted by computational studies and recently demonstrated by laboratory experiments. Such trapped water may…

Astrophysics of Galaxies · Physics 2024-02-22 Alexey Potapov , Cornelia Jäger , Harald Mutschke , Thomas Henning

Vitrification during cryopreservation requires a detailed understanding of the dynamic behavior of biological solutions. We investigate ferritin diffusion in glycerol-water mixtures at supercooled temperatures using X-ray Photon Correlation…

This paper investigates by in situ high-resolution X-ray radiography and tomography the behaviour of colloidal suspensions of alumina particles during directional solidification by freezing. The combination of these techniques provided both…

Demand for artificial body implants has been on the rise over the years. However, wear and bacterial infection are identified as two major reasons that can lead to inflammation and implant failure. In this communication, the advantages of…

Biological Physics · Physics 2022-07-27 S. Kedia , A. Das , B. S. Patro , J. P. Nilaya

The proneness of water to crystallize is a major obstacle to understanding its putative exotic behavior in the supercooled state. It also represents a strong practical limitation to cryopreservation of biological systems. Adding some…

‹ Prev 1 2 3 10 Next ›