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The field of Clinical-Computational Nuclear Medicine is rapidly advancing, fueled by AI, tracer kinetic modeling, radiomics, and integrated informatics. These technologies improve imaging quality, automate lesion detection, and enable…

The healthcare industry has a growing need for realistic modeling and efficient simulation of surgical scenes. With effective models of deformable surgical scenes, clinicians are able to conduct surgical planning and surgery training on…

Image and Video Processing · Electrical Eng. & Systems 2024-04-25 Yuehao Wang , Bingchen Gong , Yonghao Long , Siu Hin Fan , Qi Dou

Radiotherapy is a commonly used treatment for cancer and is usually given in varying doses. At low radiation doses relatively few cells die as a direct response to radiation but secondary radiation effects such as DNA mutation or bystander…

Quantitative Methods · Quantitative Biology 2016-06-16 Gibin G Powathil , Alastair J Munro , Mark AJ Chaplain , Maciej Swat

Purpose. Given the high level of expertise required for navigation and interpretation of ultrasound images, computational simulations can facilitate the training of such skills in virtual reality. With ray-tracing based simulations,…

Image and Video Processing · Electrical Eng. & Systems 2021-01-22 Lin Zhang , Tiziano Portenier , Orcun Goksel

The electromagnetic radiation of a rotating relativistic electron layers is studied numerically using particle-in-cell simulation. The results of the simulation confirm all relevant scaling properties predicted by theoretical models. These…

Astrophysics · Physics 2007-05-23 Bjoern S. Schmekel

Cardiotoxicity induced by cancer treatment has become a major clinical concern, affecting the long-term survival and quality of life of cancer patients. Effective clinical decision-making, including the detection of cancer treatment-induced…

Human-Computer Interaction · Computer Science 2024-08-08 Siyi Wu , Weidan Cao , Shihan Fu , Bingsheng Yao , Ziqi Yang , Changchang Yin , Varun Mishra , Daniel Addison , Ping Zhang , Dakuo Wang

Intensity Modulated Radiation Therapy is an effective cancer treatment. Models based on the Generalized Equivalent Uniform Dose (gEUD) provide radiation plans with excellent planning target volume coverage and low radiation for organs at…

Since decades, many techniques have been developed for curing cancer. Here, an effort has been made to cure tumor by inserting a cryoprobe into the target region which is connected to a cryogenic mechanism. This technique is presently used…

Medical Physics · Physics 2022-12-23 G Sai Krishna , Anup Paul

Quantum networks are advancing the information technology infrastructure of society. Simulation and emulation software tools have emerged to support the design, development, and deployment of quantum networks, however, classical simulation…

Quantum Physics · Physics 2026-03-03 Brian Doolittle , Michael Cubeddu

The method of microwave radiometry is one of the areas of medical diagnosis of breast cancer. It is based on analysis of the spatial distribution of internal and surface tissue temperatures, which are measured in the microwave (RTM) and…

Quantitative Methods · Quantitative Biology 2019-10-08 Vladislav Levshinskii , Maxim Polyakov , Alexander Losev , Alexander Khoperskov

Immunotherapies have been proven to have significant therapeutic efficacy in the treatment of cancer. The last decade has seen adoptive cell therapies, such as chimeric antigen receptor T-cell (CART-cell) therapy, gain FDA approval against…

Molecular Networks · Quantitative Biology 2023-02-10 Viren Shah , Justin Womack , Anthony E. Zamora , Scott S. Terhune , Ranjan K. Dash

Radiomics is a nascent field in quantitative imaging that uses advanced algorithms and considerable computing power to describe tumor phenotypes, monitor treatment response, and assess normal tissue toxicity quantifiably. Remarkable…

Medical Physics · Physics 2019-11-26 Jiwoong Jeong , Arif Ali , Tian Liu , Hui Mao , Walter J. Curran , Xiaofeng Yang

Theranostics, the combination of diagnosis and therapy, has long held promise as a means to achieving personalised precision cancer treatments. However, despite its potential, theranostics has yet to realise significant clinical…

Computer-Aided Diagnosis and Treatment of Tumors is a hot topic of deep learning in recent years, which constitutes a series of medical tasks, such as detection of tumor markers, the outline of tumor leisures, subtypes and stages of tumors,…

Image and Video Processing · Electrical Eng. & Systems 2020-11-03 Dan Zhao , Guizhi Xu , Zhenghua XU , Thomas Lukasiewicz , Minmin Xue , Zhigang Fu

Real-time computer-aided diagnosis using artificial intelligence (AI), with images, can help oncologists diagnose cancer with high accuracy and in an early phase. We reviewed real-time AI-based analyzed images for decision-making in…

Image and Video Processing · Electrical Eng. & Systems 2025-03-17 Leila Bagheriye , Johan Kwisthout

Intensity-modulated radiation therapy (IMRT) allows for the design of customized, highly-conformal treatments for cancer patients. Creating IMRT treatment plans, however, is a mathematically complex process, which is often tackled in…

Optimization and Control · Mathematics 2022-03-18 Danielle A. Ripsman , Thomas G. Purdie , Timothy C. Y. Chan , Houra Mahmoudzadeh

Background: Radiotherapy outcomes are usually predicted using the Linear Quadratic model. However, this model does not integrate complex features of tumor growth, in particular cell cycle regulation. Methods: In this paper, we propose a…

Tissues and Organs · Quantitative Biology 2007-05-23 Benjamin Ribba , Thierry Colin , Santiago Schnell

Accurate, reproducible burn assessment is critical for treatment planning, healing monitoring, and medico-legal documentation, yet conventional visual inspection and 2D photography are subjective and limited for longitudinal comparison.…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 S. Kalaycioglu , C. Hong , K. Zhai , H. Xie , J. N. Wong

Purpose: This study explores the feasibility of dose-escalated proton beam therapy (dPBT) for Locally Advanced Pancreatic Cancer (LAPC) patients by modeling common patient scenarios using current clinically-adopted practices. Methods: Five…

Medical Physics · Physics 2025-07-30 M. A. McIntyre , J. Midson , P. Wilson , P Gorayski , C. E. Hsieh , S. W. Wu , E. Bezak

In this study, we conduct a study on magnetic hyperthermia treatment when a vessel is located near the tumor. The holistic framework is established to solve the process of tumor treatment. The interstitial tissue fluid, MNP distribution,…