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We describe an approach for incorporating radiative transfer into 3D hydrodynamic cosmological simulations. The method, while approximate, allows for a self-consistent treatment of self-shielding and shadowing, diffuse and point sources of…

Astrophysics · Physics 2007-05-23 Michael L. Norman , Paschalis Paschos , Tom Abel

We present a novel application of Tensor Network methods in cancer treatment as a potential tool to solve the dose optimization problem in radiotherapy. In particular, the Intensity-Modulated Radiation Therapy (IMRT) technique - that allows…

Medical Physics · Physics 2021-08-11 Samuele Cavinato , Timo Felser , Marco Fusella , Marta Paiusco , Simone Montangero

A software for processing sets of full-color images of biological tissue histological sections is developed. We used histological sections obtained by the method of high-precision layer-by-layer grinding of frozen biological tissues. The…

In recent years, volumetric modulated arc therapy (VMAT) has been becoming a more and more important radiation technique widely used in clinical application for cancer treatment. One of the key problems in VMAT is treatment plan…

Medical Physics · Physics 2016-01-06 Yu Yang , Bin Dong , Zaiwen Wen

Recent developments for the delivery of proton and ion beam therapy have been significant, and a number of technological solutions now exist for the creation and utilisation of these particles for the treatment of cancer. In this paper we…

Accelerator Physics · Physics 2015-06-17 Hywel Owen , David Holder , Jose Alonso , Ranald MacKay

Longitudinal tumour volume data from head-and-neck cancer patients show that tumours of comparable pre-treatment size and stage may respond very differently to the same radiotherapy fractionation protocol. Mathematical models are often…

In this work, we present a fundamental mathematical model for proton transport, tailored to capture the key physical processes underpinning Proton Beam Therapy (PBT). The model provides a robust and computationally efficient framework for…

The importance of computers is continually increasing in radiotherapy. Efficient algorithms, implementations and the ability to leverage advancements in computer science are crucial to improve cancer care even further and deliver the best…

Medical Physics · Physics 2024-07-08 Renato Bellotti , Antony J. Lomax , Andreas Adelmann , Jan Hrbacek

Current clinical decision-making in oncology relies on averages of large patient populations to both assess tumor status and treatment outcomes. However, cancers exhibit an inherent evolving heterogeneity that requires an individual…

Efficiently acquired and precisely reconstructed imaging are crucial to the success of modern radiation therapy (RT). Computed tomography (CT) and magnetic resonance imaging (MRI) are two common modalities for providing RT treatment…

Image and Video Processing · Electrical Eng. & Systems 2025-04-15 Di Xu

A modular, maintainable and extensible particle beam simulation architecture is presented. Design considerations for single particle, multi particle, and rms envelope simulations (in two and three dimensions) are outlined. Envelope…

Computational Physics · Physics 2007-05-23 Nicholas D. Pattengale , Christopher K. Allen

Medical imaging modalities have revolutionized health-care approaches by offering a better understanding of the human anatomy. Discovery of x-rays allowed the exploiting of the micro-scaled information of human anatomy. Computed tomography…

Medical Physics · Physics 2018-09-18 Sanam Assili

Interrupted X-ray computed tomography (X-CT) has been the common way to observe the deformation of materials during an experiment. While this approach is effective for quasi-static experiments, it has never been possible to reconstruct a…

Instrumentation and Detectors · Physics 2024-10-29 Ivan Grega , William F. Whitney , Vikram S. Deshpande

Cancer is a disease driven by random DNA mutations and the interaction of many complex phenomena. To improve the understanding and ultimately find more effective treatments, researchers leverage computer simulations mimicking the tumor…

Computational Physics · Physics 2024-01-26 Tobias Duswald , Ernesto A. B. F. Lima , J. Tinsley Oden , Barbara Wohlmuth

We present a fast and reliable algorithm that gives precise location of breast tumours for a partial mastectomy. Our algorithm is fully implemented in the Surface Evolver, which is a general-purpose simulator of physical experiments. By…

Image and Video Processing · Electrical Eng. & Systems 2019-12-02 Marcelo Zanchetta do Nascimento , Valério Ramos Batista

Computational multiscale modeling encompasses a wide range of end-products and a great number of technological applications. This paper provides an overview of the computational multiscale modeling approach based on the utilization of MBN…

Computational Physics · Physics 2021-07-23 Alexey V. Verkhovtsev , Ilia A. Solov'yov , Andrey V. Solov'yov

Conventional breast cancer imaging techniques are nowadays based on the use of ionising radiations or ultrasound waves for the inspection of breast areas. Nevertheless, these conventional techniques present some drawbacks related to patient…

Image and Video Processing · Electrical Eng. & Systems 2023-03-07 Michele Ambrosanio , Stefano Franceschini , Vito Pascazio , Fabio Baselice

Radiotherapy is a crucial cancer treatment that demands precise planning to balance tumor eradication and preservation of healthy tissue. Traditional treatment planning (TP) is iterative, time-consuming, and reliant on human expertise,…

Machine Learning · Computer Science 2025-02-10 Matteo Ferrante , Alessandra Carosi , Rolando Maria D Angelillo , Nicola Toschi

In robotic radiation therapy, high-energy photon beams from different directions are directed at a target within the patient. Target motion can be tracked by robotic ultrasound and then compensated by synchronous beam motion. However,…

Computational Engineering, Finance, and Science · Computer Science 2024-03-29 Lars Beckers , Stefan Gerlach , Ole Lübke , Alexander Schlaefer , Sibylle Schupp

Purpose: Radio-frequency ablations play an important role in the therapy of malignant liver lesions. The navigation of a needle to the lesion poses a challenge for both the trainees and intervening physicians. Methods: This publication…

Medical Physics · Physics 2019-07-18 Niclas Kath , Heinz Handels , Andre Mastmeyer
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