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Related papers: Resting-state ASL : Toward an optimal sequence dur…

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Discovery of sensitive and biologically grounded biomarkers is essential for early detection and monitoring of Alzheimer's disease (AD). Structural MRI is widely available but typically relies on hand-crafted features such as cortical…

A brain microstate is characterized by a unique, fixed spatial distribution of electrically active neurons with time varying amplitude. It is hypothesized that a microstate implements a functional/physiological state of the brain during…

Early clinical assessment of Alzheimer's disease relies on behavior scores that measure a subject's language, memory, and cognitive skills. On the medical imaging side, functional magnetic resonance imaging has provided invaluable insights…

Signal Processing · Electrical Eng. & Systems 2026-04-14 Javier Salazar Cavazos , Maximillian Egan , Krisanne Litinas , Benjamin Hampstead , Scott Peltier

Image segmentation is one of the most essential biomedical image processing problems for different imaging modalities, including microscopy and X-ray in the Internet-of-Medical-Things (IoMT) domain. However, annotating biomedical images is…

Computer Vision and Pattern Recognition · Computer Science 2021-01-25 Ziyuan Zhao , Zeng Zeng , Kaixin Xu , Cen Chen , Cuntai Guan

Fractals are self-similar and scale-invariant patterns found ubiquitously in nature. A lot of evidences implying fractal properties such as 1/f power spectrums have been also observed in resting state fMRI time series. To explain the…

Applications · Statistics 2012-08-07 Wonsang You , Jörg Stadler

Dynamic functional connectivity (DFC) analysis involves measuring correlated neural activity over time across multiple brain regions. Significant regional correlations among neural signals, such as those obtained from resting-state…

Anatomical and functional brain studies have converged to the hypothesis that Autism Spectrum Disorders (ASD) are associated with atypical connectivity. Using a modified resting-state paradigm to drive subjects' attention, we provide…

Neurons and Cognition · Quantitative Biology 2012-11-21 Pablo Barttfeld , Bruno Wicker , Sebastián Cukier , Silvana Navarta , Sergio Lew , Ramón Leiguarda , Mariano Sigman

We propose a novel optimization framework to predict clinical severity from resting state fMRI (rs-fMRI) data. Our model consists of two coupled terms. The first term decomposes the correlation matrices into a sparse set of representative…

Neurons and Cognition · Quantitative Biology 2024-11-25 Niharika Shimona D'Souza , Mary Beth Nebel , Nicholas Wymbs , Stewart H. Mostofsky , Archana Venkataraman

The method of Arterial Spin Labeling (ASL) has experienced a significant rise in its application to functional imaging, since it is the only technique capable of measuring blood perfusion in a truly non-invasive manner. Currently, there are…

Software Engineering · Computer Science 2024-01-24 Virginia Mato Abad , Pablo Garcia-Polo , Owen ODaly , Juan Antonio Hernandez-Tamames , Fernando Zelaya

The Blood-Oxygen-Level-Dependent (BOLD) signal of resting-state fMRI (rs-fMRI) records the temporal dynamics of intrinsic functional networks in the brain. However, existing deep learning methods applied to rs-fMRI either neglect the…

Machine Learning · Computer Science 2021-06-30 Soham Gadgil , Qingyu Zhao , Adolf Pfefferbaum , Edith V. Sullivan , Ehsan Adeli , Kilian M. Pohl

This paper describes an approach of using dynamic Structural Equation Modeling (SEM) analysis to estimate the connectivity networks from resting-state fMRI data measured by a multiband EPI sequence. Two structural equation models were…

Neurons and Cognition · Quantitative Biology 2017-04-03 Jiancheng Zhuang

Machine learning analysis of longitudinal neuroimaging data is typically based on supervised learning, which requires a large number of ground-truth labels to be informative. As ground-truth labels are often missing or expensive to obtain…

Machine Learning · Computer Science 2021-06-29 Qingyu Zhao , Zixuan Liu , Ehsan Adeli , Kilian M. Pohl

Neuro-symbolic learning (NSL) models complex symbolic rule patterns into latent variable distributions by neural networks, which reduces rule search space and generates unseen rules to improve downstream task performance. Centralized NSL…

Artificial Intelligence · Computer Science 2024-05-28 Pengwei Xing , Songtao Lu , Han Yu

There has been increasing interests in learning resting-state brain functional connectivity of autism disorders using functional magnetic resonance imaging (fMRI) data. The data in a standard brain template consist of over 200,000 voxel…

Methodology · Statistics 2016-03-22 Jichun Xie , Jian Kang

Learning useful information across long time lags is a critical and difficult problem for temporal neural models in tasks such as language modeling. Existing architectures that address the issue are often complex and costly to train. The…

Computation and Language · Computer Science 2017-07-18 Alexander G. Ororbia , Tomas Mikolov , David Reitter

Purpose : Because functional MRI (fMRI) data sets are in general small, we sought a data efficient approach to resting state fMRI classification of autism spectrum disorder (ASD) versus neurotypical (NT) controls. We hypothesized that a…

Neurons and Cognition · Quantitative Biology 2022-06-23 Joseph Stember , Danielle Stember , Luca Pasquini , Jenabi Merhnaz , Andrei Holodny , Hrithwik Shalu

Resting-state functional magnetic resonance imaging (fMRI) has emerged as a pivotal tool for revealing intrinsic brain network connectivity and identifying neural biomarkers of neuropsychiatric conditions. However, classical self-attention…

Image and Video Processing · Electrical Eng. & Systems 2025-09-03 Junghoon Justin Park , Jungwoo Seo , Sangyoon Bae , Samuel Yen-Chi Chen , Huan-Hsin Tseng , Jiook Cha , Shinjae Yoo

Prolonged alcohol use results in neuroadaptations that mark more severe and treatment-resistant alcohol use. The goal of this study was to identify functional connectivity brain patterns underlying Alcohol Use Disorder (AUD)-related…

Large Language Models (LLMs) have demonstrated strong semantic reasoning across multimodal domains. However, their integration with graph-based models of brain connectivity remains limited. In addition, most existing fMRI analysis methods…

Image and Video Processing · Electrical Eng. & Systems 2026-05-27 Yasaman Torabi , Parsa Razmara , Hamed Ajorlou , Bardia Baraeinejad

Mesial temporal lobe epilepsy (mTLE) is the most common form of epilepsy. While it is characterized by an epileptogenic focus in the mesial temporal lobe, it is increasingly understood as a network disorder. Hence, understanding the nature…

Neurons and Cognition · Quantitative Biology 2020-09-28 Nishad Singhi , Hritik Bansal