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Knowledge tracing---where a machine models the knowledge of a student as they interact with coursework---is a well established problem in computer supported education. Though effectively modeling student knowledge would have high…

Artificial Intelligence · Computer Science 2015-06-22 Chris Piech , Jonathan Spencer , Jonathan Huang , Surya Ganguli , Mehran Sahami , Leonidas Guibas , Jascha Sohl-Dickstein

Stochastic reaction networks are mathematical models with a wide range of applications in biochemistry, ecology, and epidemiology, and are often complex to analyze. Except for some special cases, it is generally difficult to predict how the…

Probability · Mathematics 2026-04-02 Daniele Cappelletti , Giulio Cuniberti , Paola Siri

Well-mixed chemical reaction networks (CRNs) contain many distinct chemical species with copy numbers that fluctuate in correlated ways. While those correlations are typically monitored via Monte Carlo sampling of stochastic trajectories,…

Statistical Mechanics · Physics 2026-01-14 John P. Zima , Schuyler B. Nicholson , Todd R. Gingrich

In this paper I present some of the most representative biological models applied to robotics. In particular, this work represents a survey of some models inspired, or making use of concepts, by gene regulatory networks (GRNs): these…

Other Computer Science · Computer Science 2017-12-07 Michele Braccini

Here, we demonstrate how machine learning enables the prediction of comonomers reactivity ratios based on the molecular structure of monomers. We combined multi-task learning, multi-inputs, and Graph Attention Network to build a model…

Machine Learning · Computer Science 2023-01-04 Tung Nguyen , Mona Bavarian

What might sound like the beginning of a joke has become an attractive prospect for many cognitive scientists: the use of deep neural network models (DNNs) as models of human behavior in perceptual and cognitive tasks. Although DNNs have…

Artificial Intelligence · Computer Science 2020-05-06 Wei Ji Ma , Benjamin Peters

A method which casts the chemical source term computation into an artificial neural network (ANN)-inspired form is presented. This approach is well-suited for use on emerging supercomputing platforms that rely on graphical processing units…

Chemical Physics · Physics 2021-05-11 Shivam Barwey , Venkat Raman

Prediction and control of chemical mixing are vital for many scientific areas such as subsurface reactive transport, climate modeling, combustion, epidemiology, and pharmacology. Due to the complex nature of mixing in heterogeneous and…

Machine Learning · Computer Science 2021-12-15 N. V. Jagtap , M. K. Mudunuru , K. B. Nakshatrala

Machine learning techniques for road networks hold the potential to facilitate many important transportation applications. Graph Convolutional Networks (GCNs) are neural networks that are capable of leveraging the structure of a road…

Machine Learning · Computer Science 2020-07-23 Tobias Skovgaard Jepsen , Christian S. Jensen , Thomas Dyhre Nielsen

How smart can a micron-sized bag of chemicals be? How can an artificial or real cell make inferences about its environment? From which kinds of probability distributions can chemical reaction networks sample? We begin tackling these…

Molecular Networks · Quantitative Biology 2020-06-05 William Poole , Andrés Ortiz-Muñoz , Abhishek Behera , Nick S. Jones , Thomas E. Ouldridge , Erik Winfree , Manoj Gopalkrishnan

Artificial neural network (ANN) has been widely used due to its strong nonlinear mapping ability, fault tolerance and self-learning ability. This article summarizes the development history of artificial neural networks, introduces three…

Systems and Control · Electrical Eng. & Systems 2021-10-12 Fei Liang , Taowen Zhang

Machine learning plays an increasingly important role in many areas of chemistry and materials science, e.g. to predict materials properties, to accelerate simulations, to design new materials, and to predict synthesis routes of new…

In the field of molecular computation based on chemical reaction networks (CRNs), leveraging parallelism to enable coupled mass-action systems (MASs) to retain predefined computational functionality has been a research focus. MASs…

Dynamical Systems · Mathematics 2025-10-16 Renlei Jiang , Chuanhou Gao , Denis Dochain

RNAs play crucial and versatile roles in biological processes. Computational prediction approaches can help to understand RNA structures and their stabilizing factors, thus providing information on their functions, and facilitating the…

Biological Physics · Physics 2020-09-04 Bin Huang , Yuanyang Du , Shuai Zhang , Wenfei Li , Jun Wang , Jian Zhang

The ability to reason beyond established knowledge allows Organic Chemists to solve synthetic problems and to invent novel transformations. Here, we propose a model which mimics chemical reasoning and formalises reaction prediction as…

Artificial Intelligence · Computer Science 2017-12-27 Marwin H. S. Segler , Mark P. Waller

We initiate the study of rate-constant-independent computation of Boolean predicates and numerical functions in the continuous model of chemical reaction networks (CRNs), which model the amount of a chemical species as a nonnegative,…

Computational Complexity · Computer Science 2025-06-10 Kim Calabrese , David Doty , Mina Latifi

Astrochemical modeling is needed for understanding the formation and evolution of interstellar molecules, and for extracting physical information from spectroscopic observations of interstellar clouds. The modeling usually involves handling…

Solar and Stellar Astrophysics · Physics 2021-05-05 Fujun Du

We propose a direct optimization framework for learning reduced and sparse chemical reaction networks (CRNs) from time-series trajectory data. In contrast to widely used indirect methods-such as those based on sparse identification of…

Molecular Networks · Quantitative Biology 2025-08-27 Maurice Filo , Mustafa Khammash

Chemical kinetics and reaction engineering consists of the phenomenological framework for the disentanglement of reaction mechanisms, optimization of reaction performance and the rational design of chemical processes. Here, we utilize…

Machine Learning · Computer Science 2021-12-10 Gabriel S. Gusmão , Adhika P. Retnanto , Shashwati C. da Cunha , Andrew J. Medford

We analyze the computational complexity of basic reconfiguration problems for the recently introduced surface Chemical Reaction Networks (sCRNs), where ordered pairs of adjacent species nondeterministically transform into a different…

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