English

Computational prediction of RNA tertiary structures using machine learning methods

Biological Physics 2020-09-04 v1 Artificial Intelligence

Abstract

RNAs play crucial and versatile roles in biological processes. Computational prediction approaches can help to understand RNA structures and their stabilizing factors, thus providing information on their functions, and facilitating the design of new RNAs. Machine learning (ML) techniques have made tremendous progress in many fields in the past few years. Although their usage in protein-related fields has a long history, the use of ML methods in predicting RNA tertiary structures is new and rare. Here, we review the recent advances of using ML methods on RNA structure predictions and discuss the advantages and limitation, the difficulties and potentials of these approaches when applied in the field.

Keywords

Cite

@article{arxiv.2009.01440,
  title  = {Computational prediction of RNA tertiary structures using machine learning methods},
  author = {Bin Huang and Yuanyang Du and Shuai Zhang and Wenfei Li and Jun Wang and Jian Zhang},
  journal= {arXiv preprint arXiv:2009.01440},
  year   = {2020}
}

Comments

20 pages, 2 figures. Chinese Physics B, Aug. 2020

R2 v1 2026-06-23T18:17:03.710Z