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In addition to color and textural information, geometry provides important cues for 3D scene reconstruction. However, current reconstruction methods only include geometry at the feature level thus not fully exploiting the geometric…

Computer Vision and Pattern Recognition · Computer Science 2024-08-29 Ruihong Yin , Sezer Karaoglu , Theo Gevers

We propose CrossHuman, a novel method that learns cross-guidance from parametric human model and multi-frame RGB images to achieve high-quality 3D human reconstruction. To recover geometry details and texture even in invisible regions, we…

Computer Vision and Pattern Recognition · Computer Science 2022-07-21 Liliang Chen , Jiaqi Li , Han Huang , Yandong Guo

Cryo-Electron Microscopy (Cryo-EM) is a Nobel prize-winning technology for determining the 3D structure of particles at near-atomic resolution. A fundamental step in the recovering of the 3D single-particle structure is to align its 2D…

Image and Video Processing · Electrical Eng. & Systems 2021-01-12 Koby Bibas , Gili Weiss-Dicker , Dana Cohen , Noa Cahan , Hayit Greenspan

The past decade has seen a revolution in genomic technologies that enable a flood of genome-wide profiling of chromatin marks. Recent literature tried to understand gene regulation by predicting gene expression from large-scale chromatin…

Machine Learning · Computer Science 2017-11-08 Ritambhara Singh , Jack Lanchantin , Arshdeep Sekhon , Yanjun Qi

One of the most important problems in development is how epigenetic domains can be first established, and then maintained, within cells. To address this question, we propose a framework which couples 3D chromatin folding dynamics, to a…

Soft Condensed Matter · Physics 2016-10-25 Davide Michieletto , Enzo Orlandini , Davide Marenduzzo

Humans build 3D understandings of the world through active object exploration, using jointly their senses of vision and touch. However, in 3D shape reconstruction, most recent progress has relied on static datasets of limited sensory data…

Computer Vision and Pattern Recognition · Computer Science 2021-10-27 Edward J. Smith , David Meger , Luis Pineda , Roberto Calandra , Jitendra Malik , Adriana Romero , Michal Drozdzal

Chromatin conformation capture technologies such as Hi-C have revealed that the genome is organized in a hierarchy of structures spanning multiple scales observed at different resolutions. Current algorithms often focus on specific…

Genomics · Quantitative Biology 2025-12-22 Vipin Kumar , Roberto Rossini , Jonas Paulsen , Anthony Mathelier

Inspired by recent findings that generative diffusion models learn semantically meaningful representations, we use them to discover the intrinsic hierarchical structure in biomedical 3D images using unsupervised segmentation. We show that…

Computer Vision and Pattern Recognition · Computer Science 2023-10-11 Nurislam Tursynbek , Marc Niethammer

Studying cell morphology changes in time is critical to understanding cell migration mechanisms. In this work, we present a deep learning-based workflow to segment cancer cells embedded in 3D collagen matrices and imaged with phase-contrast…

Computer Vision and Pattern Recognition · Computer Science 2021-12-17 Estibaliz Gómez-de-Mariscal , Hasini Jayatilaka , Özgün Çiçek , Thomas Brox , Denis Wirtz , Arrate Muñoz-Barrutia

The question of representation of 3D geometry is of vital importance when it comes to leveraging the recent advances in the field of machine learning for geometry processing tasks. For common unstructured surface meshes state-of-the-art…

Computer Vision and Pattern Recognition · Computer Science 2018-09-28 Isaak Lim , Alexander Dielen , Marcel Campen , Leif Kobbelt

The inapplicability of amino acid covariation methods to small protein families has limited their use for structural annotation of whole genomes. Recently, deep learning has shown promise in allowing accurate residue-residue contact…

Biomolecules · Quantitative Biology 2019-09-10 Joe G Greener , Shaun M Kandathil , David T Jones

Cellular processes are governed by macromolecular complexes inside the cell. Study of the native structures of macromolecular complexes has been extremely difficult due to lack of data. With recent breakthroughs in Cellular electron cryo…

Quantitative Methods · Quantitative Biology 2018-06-12 Chengqian Che , Ruogu Lin , Xiangrui Zeng , Karim Elmaaroufi , John Galeotti , Min Xu

Apart from being the gateway for all access to the eukaryotic genome, chromatin has in recent years been identified as carrying an epigenetic code regulating transcriptional activity. The detailed knowledge of this code contrasts the…

Other Quantitative Biology · Quantitative Biology 2007-12-07 Martin Depken , Helmut Schiessel

Automatic 3D neuron reconstruction is critical for analysing the morphology and functionality of neurons in brain circuit activities. However, the performance of existing tracing algorithms is hinged by the low image quality. Recently, a…

Image and Video Processing · Electrical Eng. & Systems 2021-09-17 Heng Wang , Chaoyi Zhang , Jianhui Yu , Yang Song , Siqi Liu , Wojciech Chrzanowski , Weidong Cai

Anatomical trees play an important role in clinical diagnosis and treatment planning. Yet, accurately representing these structures poses significant challenges owing to their intricate and varied topology and geometry. Most existing…

Image and Video Processing · Electrical Eng. & Systems 2025-09-18 Paula Feldman , Miguel Fainstein , Viviana Siless , Claudio Delrieux , Emmanuel Iarussi

Spectrum map construction, which is crucial in cognitive radio (CR) system, visualizes the invisible space of the electromagnetic spectrum for spectrum-resource management and allocation. Traditional reconstruction methods are generally for…

Signal Processing · Electrical Eng. & Systems 2024-03-14 Wang Jie , Lin Zhipeng , Zhu Qiuming , Wu Qihui , Lan Tianxu , Zhao Yi , Bai Yunpeng , Zhong Weizhi

To understand the nature of a cell, one needs to understand the structure of its genome. For this purpose, experimental techniques such as Hi-C detecting chromosomal contacts are used to probe the three-dimensional genomic structure. These…

Quantitative Methods · Quantitative Biology 2019-09-23 Andreas Hofmann , Fatema Zahra Rashid , Frédéric Crémazy , Remus T. Dame , Dieter W. Heermann

How long threadlike eukaryotic chromosomes fit tidily in the small volume of the nucleus without significant entanglement is just beginning to be understood, thanks to major advances in experimental techniques. Several polymer models, which…

Soft Condensed Matter · Physics 2024-10-03 D. Thirumalai , Guang Shi , Sucheol Shin , Changbong Hyeon

We present a novel adaptive machine-learning based approach for reconstructing three-dimensional (3D) crystals from coherent diffraction imaging (CDI). We represent the crystals using spherical harmonics (SH) and generate corresponding…

Computational Physics · Physics 2020-12-02 Alexander Scheinker , Reeju Pokharel

Understanding 3d human interactions is fundamental for fine-grained scene analysis and behavioural modeling. However, most of the existing models predict incorrect, lifeless 3d estimates, that miss the subtle human contact aspects--the…

Computer Vision and Pattern Recognition · Computer Science 2023-08-07 Mihai Fieraru , Mihai Zanfir , Elisabeta Oneata , Alin-Ionut Popa , Vlad Olaru , Cristian Sminchisescu