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The transient signal available for hyperpolarized (HP) 13C imaging limits the image spatial resolution. This paper demonstrates a method of increasing spatial resolution by post-processing the HP 13C metabolic map using a corresponding…

Medicine is evolving beyond therapy largely predicated on anatomical information and towards incorporating patient-specific molecular biomarkers of disease for more accurate diagnosis and effective treatment. The complementary combination…

Magnetic Resonance Spectroscopic Imaging (MRSI) is a valuable tool for studying metabolic activities in the human body, but the current applications are limited to low spatial resolutions. The existing deep learning-based MRSI…

Image and Video Processing · Electrical Eng. & Systems 2022-06-22 Siyuan Dong , Gilbert Hangel , Wolfgang Bogner , Georg Widhalm , Karl Rössler , Siegfried Trattnig , Chenyu You , Robin de Graaf , John Onofrey , James Duncan

Hyperpolarized 13C-MRI allows real time observation of metabolism in vivo. Imaging sequences have been developed to follow the metabolism of [1-13C] pyruvate and extract reaction kinetics, which can show tumour treatment response. We…

Biomolecules · Quantitative Biology 2018-01-08 Junzhe Zhao

Purpose: Hyperpolarized imaging experiments have conflicting requirements of high spatial, temporal, and spectral resolution. Spectral-Spatial RF excitation has been shown to form an attractive magnetization-efficient method for…

MRI with hyperpolarized (HP) 13C agents, also known as HP 13C MRI, can measure processes such as localized metabolism that is altered in numerous cancers, liver, heart, kidney diseases, and more. It has been translated into human studies…

Magnetic Resonance Spectroscopic Imaging (MRSI) is an essential tool for quantifying metabolites in the body, but the low spatial resolution limits its clinical applications. Deep learning-based super-resolution methods provided promising…

Image and Video Processing · Electrical Eng. & Systems 2022-07-22 Siyuan Dong , Gilbert Hangel , Eric Z. Chen , Shanhui Sun , Wolfgang Bogner , Georg Widhalm , Chenyu You , John A. Onofrey , Robin de Graaf , James S. Duncan

Dynamic imaging is a beneficial tool for interventions to assess physiological changes. Nonetheless during dynamic MRI, while achieving a high temporal resolution, the spatial resolution is compromised. To overcome this spatio-temporal…

Image and Video Processing · Electrical Eng. & Systems 2021-10-26 Chompunuch Sarasaen , Soumick Chatterjee , Mario Breitkopf , Georg Rose , Andreas Nürnberger , Oliver Speck

Whole-brain proton magnetic resonance spectroscopic imaging (1H-MRSI) is a non-invasive technique for assessing neurochemical distribution in the brain, offering valuable insights into brain functions and neural diseases. It greatly…

Medical Physics · Physics 2024-10-08 Zhiwei Huang , Uzay Emir , Andre Doring , Antoine Klauser , Ying Xiao , Mark Widmaier , Lijing Xin

Purpose: The expanded encoding model incorporates spatially- and time-varying field perturbations for correction during reconstruction. So far, these reconstructions have used the conjugate gradient method with early stopping used as…

Magnetic resonance imaging (MRI) is indispensable for diagnosing and planning treatment in various medical conditions due to its ability to produce multi-series images that reveal different tissue characteristics. However, integrating these…

Image and Video Processing · Electrical Eng. & Systems 2024-12-11 Churan Wang , Fei Gao , Lijun Yan , Siwen Wang , Yizhou Yu , Yizhou Wang

Magnetic resonance spectroscopic imaging (SI) is a unique imaging technique that provides biochemical information from in vivo tissues. The 1H spectra acquired from several spatial regions are quantified to yield metabolite concentrations…

Medical Physics · Physics 2019-10-23 Zohaib Iqbal , Dan Nguyen , Gilbert Hangel , Stanislav Motyka , Wolfgang Bogner , Steve Jiang

Hyperspectral Imaging (HSI) combines microscopy and spectroscopy to assess the spatial distribution of spectroscopically active compounds in objects, and has diverse applications in food quality control, pharmaceutical processes, and waste…

Image and Video Processing · Electrical Eng. & Systems 2023-08-30 Mahdiyeh Ghaffari , Mickey C. J. Lukkien , Nematollah Omidikia , Gerjen H. Tinnevelt , Marcel C. P. van Eijk , Jeroen J. Jansen

This dissertation is devoted to provide advanced nonconvex nonsmooth variational models of (Magnetic Resonance Image) MRI reconstruction, efficient learnable image reconstruction algorithms and parameter training algorithms that improve the…

Optimization and Control · Mathematics 2023-03-06 Wanyu Bian

Magnetic resonance imaging (MRI) is mainly limited by long scanning time and vulnerable to human tissue motion artifacts, in 3D clinical scenarios. Thus, k-space undersampling is used to accelerate the acquisition of MRI while leading to…

Image and Video Processing · Electrical Eng. & Systems 2022-01-11 Shengke Xue , Ruiliang Bai , Xinyu Jin

Compressed sensing (CS) theory assures us that we can accurately reconstruct magnetic resonance images using fewer k-space measurements than the Nyquist sampling rate requires. In traditional CS-MRI inversion methods, the fact that the…

Computer Vision and Pattern Recognition · Computer Science 2018-03-28 Liyan Sun , Zhiwen Fan , Xinghao Ding , Congbo Cai , Yue Huang , John Paisley

Magnetic resonance imaging (MRI) is widely used for screening, diagnosis, image-guided therapy, and scientific research. A significant advantage of MRI over other imaging modalities such as computed tomography (CT) and nuclear imaging is…

Image and Video Processing · Electrical Eng. & Systems 2020-02-20 Qing Lyu , Hongming Shan , Ge Wang

Magnetic Resonance Imaging (MRI) is a valuable clinical diagnostic modality for spine pathologies with excellent characterization for infection, tumor, degenerations, fractures and herniations. However in surgery, image-guided spinal…

Image and Video Processing · Electrical Eng. & Systems 2021-02-11 Madhu Mithra K K , Sriprabha Ramanarayanan , Keerthi Ram , Mohanasankar Sivaprakasam

Compressed Sensing MRI reconstructs images of the body's internal anatomy from undersampled measurements, thereby reducing scan time. Recently, deep learning has shown great potential for reconstructing high-fidelity images from highly…

Image and Video Processing · Electrical Eng. & Systems 2025-04-07 Armeet Singh Jatyani , Jiayun Wang , Aditi Chandrashekar , Zihui Wu , Miguel Liu-Schiaffini , Bahareh Tolooshams , Anima Anandkumar

Unsupervised estimation of the dimensionality of hyperspectral microspectroscopy datasets containing pure and mixed spectral features, and extraction of their representative endmember spectra, remains a challenge in biochemical data mining.…

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