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Single-atom-resolved detection in optical lattices using quantum-gas microscopes has enabled a new generation of experiments in the field of quantum simulation. Fluorescence imaging of individual atoms has so far been achieved for bosonic…

Elastic light scattering has been extensively used to study samples showing a non uniform refraction index on lengthscales from a fraction of a micrometer to a fraction of a millimeter. Typically, a wide laser beam is sent through the…

Optics · Physics 2009-07-21 Doriano Brogioli

In Real-Time, Feedback-Driven Single Particle Tracking methods, measurements of the emission intensity from a labeled, nanometer-scale particle are used in a feedback loop to track the motion of the particle as it moves inside its native…

Optics · Physics 2025-12-03 Md Faysal Hossain , Sean B. Andersson

Tracking single fluorescent molecules has offered resolution into dynamic molecular processes at the single-molecule level. This perspective traces the evolution of single-molecule tracking, highlighting key developments across various…

Biological Physics · Physics 2026-02-24 Lance W. Q. Xu , Steve Pressé

Diffusing-Wave Spectroscopy (DWS) treats the transport of photons through turbid samples as a diffusion process, thereby making it possible to extract the dynamics of scatterers from measured correlation functions. The analysis of DWS data…

Soft Condensed Matter · Physics 2017-12-27 Zahra Fahimi , Frank Aangenendt , Panayiotis Voudouris , Johan Mattson , Hans M. Wyss

We discuss the manner in which the dynamics of tracer polystyrene chains varies with the concentration of matrix polystyrene chains dissolved in toluene. Using fluorescence correlation spectroscopy and theory, it is shown that the…

Soft Condensed Matter · Physics 2010-12-01 Ute Zettl , Matthias Ballauff , Ludger Harnau

We present a microfluidic method leading to accurate measurements of the mutual diffusion coefficient of a liquid binary mixture over the whole solute concentration range in a single experiment. This method fully exploits solvent…

Soft Condensed Matter · Physics 2017-09-21 Anne Bouchaudy , Charles Loussert , Jean-Baptiste Salmon

In this paper, we present a novel methodology to perform Bayesian inference for Cox processes in which the intensity function is driven by a diffusion process. The novelty lies in the fact that no discretization error is involved, despite…

Methodology · Statistics 2023-06-06 Flavio B. Gonçalves , Krzysztof G. Łatuszyński , Gareth O. Roberts

We (Riedel et al. Nature 2015), as well as others, have showed that some enzymes exhibit enhanced diffusion when active. In a recent PRL, (Golestanian, PRL 2015, arXiv:1508.03219) R.Golestanian theoretically examines a number of possible…

Biological Physics · Physics 2016-08-22 K. Tsekouras , C. Riedel , R. Gabizon , S. Marqusee , S. Pressé , C. Bustamante

Single molecule fluorescence tracking provides information at nm-scale and ms-temporal resolution about the dynamics and interaction of individual molecules in a biological environment. While the dynamic behavior of isolated molecules can…

Statistical Mechanics · Physics 2021-04-07 Horst-Holger Boltz , Alexei Sirbu , Nina Stelzer , Martin J. Lohse , Christof Schütte , Paolo Annibale

Single-enzyme catalysis offers a promising approach for unravelling the dynamic behaviour of individual enzymes as they undergo a reaction, revealing the complex heterogeneity that is lost in the averaged ensembles. Here we demonstrate…

Diffusion of colored dye on water saturated paper substrates has been traditionally exploited with great skill by renowned water color artists. The same physics finds more recent practical applications in paper based diagnostic devices…

Soft Condensed Matter · Physics 2020-02-27 Sankha Shuvra Das , Sumeet Kumar , Sambuddha Ghosal , Sandip Ghosal , Suman Chakraborty

Chlorophyll fluorescence (CF) is a key indicator to study plant physiology or photosynthesis efficiency. Conventionally, CF is characterized by fluorometers, which only allows ensemble measurement through wide-field detection. For imaging…

Biological Physics · Physics 2016-11-10 Yi-Chin Tseng , Shi-Wei Chu

The diffraction pattern of a single non-periodic compact object, such as a molecule, is continuous and is proportional to the square modulus of the Fourier transform of that object. When arrayed in a crystal, the coherent sum of the…

To overcome the physical barriers caused by light diffraction, super-resolution techniques are often applied in fluorescence microscopy. State-of-the-art approaches require specific and often demanding acquisition conditions to achieve…

Diffusion magnetic resonance imaging is an imaging technology designed to probe anatomical architectures of biological samples in an in vivo and non-invasive manner through measuring water diffusion. The contribution of this paper is…

Single-molecule tracking is a powerful way to look at the dynamic organization of plasma membranes. However, there are some limitations to its use. For example, it was recently observed, using numerical simulation, that time-averaging…

Quantitative Methods · Quantitative Biology 2009-11-13 Nicolas Destainville , Laurence Salome

Single molecule localization microscopy (SMLM) techniques enable imaging biological samples well beyond the diffraction limit of light, but they vary significantly in their spatial and temporal resolutions. High-order statistical analysis…

Biological Physics · Physics 2016-03-15 Shachar Schidorsky , Xiyu Yi , Yair Razvag , Yonatan Golan , Shimon Weiss , Eilon Sherman

Fluctuation in fluorescence emission of immobilized single molecule is typically ascribed to the chromophore's intrinsic structural conformations and the influence of local environmental factors. Despite extensive research over several…

Chemical Physics · Physics 2024-08-07 Aranyak Sarkar , Vinu Namboodiri , Manoj Kumbhakar

In this paper, a new method to efficiently simulate diffusion controlled second order chemical reactions is derived and applied to site-specific DNA-binding proteins. The protein enters a spherical cell and propagates via two competing…

Biological Physics · Physics 2009-11-11 Holger Merlitz , Konstantin V. Klenin , Chen-Xu Wu , Jörg Langowski