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In this paper a quantum mechanical description of the assembly/disassembly process for microtubules is proposed. We introduce creation and annihilation operators that raise or lower the microtubule length by a tubulin layer. Following that,…

Biomolecules · Quantitative Biology 2008-10-22 Vahid Rezania , Jack Tuszynski

A number of micro-scale biological flows are characterized by spatio-temporal chaos. These include dense suspensions of swimming bacteria, microtubule bundles driven by motor proteins, and dividing and migrating confluent layers of cells. A…

Fluid Dynamics · Physics 2017-08-02 Javier Urzay , Amin Doostmohammadi , Julia M. Yeomans

We develop a stochastic kinetic model of a pre-formed attachment of a mictrotuble (MT) with a cell cortex, in which the MT is tethered to the cell by a group of active motor proteins. Such an attachment is a particularly unique case of…

Subcellular Processes · Quantitative Biology 2018-10-31 Dipanwita Ghanti , Raymond W. Friddle , Debashish Chowdhury

Natural systems integrate the work of many sub-units (cells) toward a large-scale unified goal (morphological and behavioral), which can counteract the effects of unexpected experiences, damage, or simply changes in tasks demands. In this…

Active particles locally transduce energy into motion, leading to unusual and emergent behaviors. However, current synthetic particles lack sensing and adaptation mechanisms. Here, we demonstrate a novel regulation pathway, through the…

We simulate the self-propulsion of devices in a fluid in the regime of low Reynolds numbers. Each device consists of three bodies (spheres or capsules) connected with two damped harmonic springs. Sinusoidal driving forces compress the…

Computational Engineering, Finance, and Science · Computer Science 2011-08-20 Kristina Pickl , Jan Götz , Klaus Iglberger , Jayant Pande , Klaus Mecke , Ana-Suncana Smith , Ulrich Rüde

Starting from the hypothesis that the tubulin dimer is a conformationally bistable molecule - fluctuating between a curved and a straight configuration at room temperature - we develop a model for polymorphic dynamics of the microtubule…

Biomolecules · Quantitative Biology 2010-05-10 Herve Mohrbach , Albert Johner , Igor M. Kulic

We analyse the dynamics of overlapping antiparallel treadmilling microtubules in the presence of crosslinking processive motor proteins that counterbalance an external force. We show that coupling the force-dependent velocity of motors and…

Soft Condensed Matter · Physics 2015-05-30 Sudipto Muhuri , Ignacio Pagonabarraga , Jaume Casademunt

Multiphase systems are ubiquitous in engineering, biology, and materials science, where understanding their complex interactions and rheological behavior is crucial for advancing applications ranging from emulsion stability to cellular…

Fluid Dynamics · Physics 2025-10-27 Andres Santiago Espinosa-Moreno , Nicolas Moreno , Marco Ellero

Achieving control and tunability of lyotropic materials has been a long-standing goal of liquid crystal research. Here we show that the elasticity of a liquid crystal system consisting of a dense suspension of semiflexible biopolymers can…

Soft Condensed Matter · Physics 2018-01-12 Rui Zhang , Nitin Kumar , Jennifer Ross , Margaret L. Gardel , Juan J. de Pablo

Two-dimensional active nematics are often modeled using phenomenological continuum theories that describe the dynamics of the nematic director and fluid velocity through partial differential equations (PDEs). While these models provide a…

A recently introduced particle-based model for fluid dynamics with effective excluded volume interactions is analyzed in detail. The interactions are modeled by means of stochastic multiparticle collisions which are biased and depend on…

Soft Condensed Matter · Physics 2007-05-23 Thomas Ihle , Erkan Tuzel

Instabilities of fluid-fluid interfaces are ubiquitous in passive soft matter. Adding activity to the interface or either fluid can dramatically change the stability of the interface. Using experiment and theory, we investigate the…

Soft Condensed Matter · Physics 2026-02-04 Bennett C. Sessa , Federico Cao , Robert A. Pelcovits , Thomas R. Powers , Guillaume Duclos

Internally generated active stresses drive soft materials into architectures inaccessible to thermal self-assembly. We use a microtubule-based active fluid to assemble and irreversibly restructure actin-fascin networks. Subsequently, we…

Soft Condensed Matter · Physics 2026-05-13 Kyu Hwan Choi , Sattvic Ray , Reef Sweeney , Zvonimir Dogic , Sho C. Takatori

We study the nonlinear evolution of the magnetic Rayleigh-Taylor instability using three-dimensional MHD simulations. We consider the idealized case of two inviscid, perfectly conducting fluids of constant density separated by a contact…

Astrophysics · Physics 2009-11-13 James M. Stone , Thomas A. Gardiner

Active matter comprises self-driven units, such as bacteria and synthetic microswimmers, that can spontaneously form complex patterns and assemble into functional microdevices. These processes are possible thanks to the out-of-equilibrium…

Soft Condensed Matter · Physics 2021-11-17 Jens Grauer , Falko Schmidt , Jesus Pineda , Benjamin Midtvedt , Hartmut Löwen , Giovanni Volpe , Benno Liebchen

Buckling plays a critical role in the transport and dynamics of elastic microfilaments in Stokesian fluids. However, previous work has only considered filaments with homogeneous structural properties. Filament backbone stiffness can be…

Soft Condensed Matter · Physics 2023-01-20 Thomas Nguyen , Harishankar Manikantan

To study the impact of active systems on their surroundings, we introduce a model that couples an active nematic fluid to an isotropic substrate fluid via friction. We numerically show that as the active layer develops turbulence, the…

Soft Condensed Matter · Physics 2025-12-01 Gianmarco Spera , Julia M. Yeomans , Sumesh P. Thampi

We numerically study the dynamics of a passive fluid droplet confined within a microchannel whose walls are covered with a thin layer of active gel. The latter represents a fluid of extensile material modelling, for example, a suspension of…

Soft Condensed Matter · Physics 2023-08-10 A. Tiribocchi , M. Durve , M. Lauricella , A. Montessori , S. Succi

3D-printed digital materials whose mechanical behavior travels between those from thermoplastic to rubbery polymers have become increasingly important. However, their mechanical functionalities have not been fully exploited due to intrinsic…

Soft Condensed Matter · Physics 2026-03-18 Seunghwan Lee , Gisoo Lee , Seounghee Yun , Sumin Lee , Jeonyoon Lee , Hansohl Cho