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The evolution, regulation and sustenance of biological complexity is determined by protein-protein interaction network that is filled with dynamic events. Recent experimental evidences point out that clustering of proteins has a vital role…

Tissues and Organs · Quantitative Biology 2007-05-23 RV Krishnan

Proteins constitute a large group of macromolecules with a multitude of functions for all living organisms. Proteins achieve this by adopting distinct three-dimensional structures encoded by the sequence of their constituent amino acids in…

Methodology · Statistics 2021-09-16 Mohammad Arashi , Najmeh Nakhaei Rad , Andriette Bekker , Wolf Dieter Schubert

The protein folding problem must ultimately be solved on all length scales from the atomic up through a hierarchy of complicated structures. By analyzing the stability of the folding process using physics and mathematics, this paper shows…

Biological Physics · Physics 2015-05-28 Walter Simmons , Joel L. Weiner

The structure and stresses of static granular packs in cylindrical containers are studied using large-scale discrete element molecular dynamics simulations in three dimensions. We generate packings by both pouring and sedimentation and…

Soft Condensed Matter · Physics 2009-11-07 J. W. Landry , G. S. Grest , L. E. Silbert , S. J. Plimpton

The interaction of a protein with its environment can be understood and controlled via its 3D structure. Experimental methods for protein structure determination, such as X-ray crystallography or cryogenic electron microscopy, shed light on…

Machine Learning · Computer Science 2025-04-24 Axel Levy , Eric R. Chan , Sara Fridovich-Keil , Frédéric Poitevin , Ellen D. Zhong , Gordon Wetzstein

Dispersed colloidal particles within a suspension can aggregate and spontaneously self-organize into a robust, percolating structure known as a gel. These network-like structures are prevalent in nature and play a critical role in many…

Soft Condensed Matter · Physics 2025-04-29 David Richard , Mehdi Bouzid

George and Wilson [Acta. Cryst. D 50, 361 (1994)] looked at the distribution of values of the second virial coefficient of globular proteins, under the conditions at which they crystallise. They found the values to lie within a fairly…

Soft Condensed Matter · Physics 2009-11-07 Richard P. Sear

Long, flexible physical filaments are naturally tangled and knotted, from macroscopic string down to long-chain molecules. The existence of knotting in a filament naturally affects its configuration and properties, and may be very stable or…

Biomolecules · Quantitative Biology 2016-11-21 Keith Alexander , Alexander J Taylor , Mark R Dennis

Spatial heterogeneity is a hallmark of living systems, even at the molecular scale in individual cells. A key example is the partitioning of membrane-bound proteins via lipid domain formation or cytoskeleton-induced corralling. Yet the…

Molecular Networks · Quantitative Biology 2013-11-19 Andrew Mugler , Filipe Tostevin , Pieter Rein ten Wolde

Soft particulate gels include materials we can eat, squeeze, or 3D print. From foods to bio-inks to cement hydrates, these gels are composed of a small amount of particulate matter (proteins, polymers, colloidal particles, or agglomerates…

We study the percolation properties for a system of functionalized colloids on patterned substrates via Monte Carlo simulations. The colloidal particles are modeled as hard disks with three equally-distributed attractive patches on their…

Soft Condensed Matter · Physics 2018-03-02 Lucas L. Treffenstädt , Nuno A. M. Araújo , Daniel de las Heras

During hierarchical clustering, smaller masses generally collapse earlier than larger masses and so are denser on the average. The core of a small mass halo could be dense enough to resist disruption and survive undigested, when it is…

Astrophysics · Physics 2009-10-31 Kandaswamy Subramanian , Renyue Cen , Jeremiah P. Ostriker

We study the Voronoi and void statistics of super-homogeneous (or hyperuniform) point patterns in which the infinite-wavelength density fluctuations vanish. Super-homogeneous or hyperuniform point patterns arise in one-component plasmas,…

Statistical Mechanics · Physics 2016-08-31 Andrea Gabrielli , Salvatore Torquato

We investigate the distribution of the volume and coordination number associated to each particle in a jammed packing of monodisperse hard sphere using the mesoscopic ensemble developed in Nature 453, 606 (2008). Theory predicts an…

Soft Condensed Matter · Physics 2015-05-13 Ping Wang , Chaoming Song , Yuliang Jin , Kun Wang , Hernan A. Makse

Under the assumption of a void-filled Universe we investigate if the characteristic scale of voids can be determined from existing surveys. We use the Voronoi tessellation to create mock surveys and study the properties of the first…

Astrophysics · Physics 2015-06-24 Dalia S. Goldwirth , Luiz Nicolaci da Costa , Rien Van de Weygaert

Natural protein sequences somehow encode the structural forms that these molecules adopt. Recent developments in structure-prediction are agnostic to the mechanisms by which proteins fold and represent them as static objects. However, the…

Biomolecules · Quantitative Biology 2025-05-26 Ezequiel A. Galpern , Federico Caamaño , Diego U. Ferreiro

We show for the first time that collectively jammed disordered packings of three-dimensional monodisperse frictionless hard spheres can be produced and tuned using a novel numerical protocol with packing density $\phi$ as low as 0.6. This…

Statistical Mechanics · Physics 2011-01-10 Yang Jiao , Frank H. Stillinger , Sal Torquato

Protein-stabilised emulsions can be seen as mixtures of unadsorbed proteins and of protein-stabilised droplets. To identify the contributions of these two components to the overall viscosity of sodium caseinate o/w emulsions, the…

Soft Condensed Matter · Physics 2019-01-30 Marion Roullet , Paul S. Clegg , William J. Frith

We use the Magneticum suite of state-of-the-art hydrodynamical simulations to identify cosmic voids based on the watershed technique and investigate their most fundamental properties across different resolutions in mass and scale. This…

Cosmology and Nongalactic Astrophysics · Physics 2023-06-02 Nico Schuster , Nico Hamaus , Klaus Dolag , Jochen Weller

In this paper, I relate the phase separation transition in binary hard-core mixtures in the limit of small size ratio to a bond percolation transition. It allows to estimate the critical packing fraction at the transition as a function of…

Statistical Mechanics · Physics 2009-10-31 Arnaud Buhot
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