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Spatially Resolved Transcriptomics (SRT) is a cutting-edge technique that captures the spatial context of cells within tissues, enabling the study of complex biological networks. Recent graph-based methods leverage both gene expression and…

Machine Learning · Computer Science 2025-06-24 Yunhak Oh , Junseok Lee , Yeongmin Kim , Sangwoo Seo , Namkyeong Lee , Chanyoung Park

Learning in the combinatorially large output space of sequence generation problems is challenging as providing expert demonstrations scales poorly with sequence length, and RL struggles with sparse rewards. Between dense demonstrations in…

Recent advances in domain adaptation show that deep self-training presents a powerful means for unsupervised domain adaptation. These methods often involve an iterative process of predicting on target domain and then taking the confident…

Computer Vision and Pattern Recognition · Computer Science 2020-07-16 Yang Zou , Zhiding Yu , Xiaofeng Liu , B. V. K. Vijaya Kumar , Jinsong Wang

Regression trees are a popular machine learning algorithm that fit piecewise constant models by recursively partitioning the predictor space. This paper focuses on statistical inference for a data-dependent model obtained from a fitted…

Methodology · Statistics 2025-12-17 Soham Bakshi , Yiling Huang , Snigdha Panigrahi , Walter Dempsey

Student learning development must involve more than just correcting or incorrect questions. However, most adaptive learning methods in Virtual Learning Environments are based on whether the student's response is incorrect or correct. This…

Scaling issues are mundane yet irritating for practitioners of reinforcement learning. Error scales vary across domains, tasks, and stages of learning; sometimes by many orders of magnitude. This can be detrimental to learning speed and…

Machine Learning · Computer Science 2021-05-13 Tom Schaul , Georg Ostrovski , Iurii Kemaev , Diana Borsa

Large-scale pre-trained language models have contributed significantly to natural language processing by demonstrating remarkable abilities as few-shot learners. However, their effectiveness depends mainly on scaling the model parameters…

Computation and Language · Computer Science 2023-01-26 Ningyu Zhang , Luoqiu Li , Xiang Chen , Shumin Deng , Zhen Bi , Chuanqi Tan , Fei Huang , Huajun Chen

Advances in spatially-resolved transcriptomics (SRT) technologies have propelled the development of new computational analysis methods to unlock biological insights. As the cost of generating these data decreases, these technologies provide…

Genomics · Quantitative Biology 2024-08-02 Boyi Guo , Wodan Ling , Sang Ho Kwon , Pratibha Panwar , Shila Ghazanfar , Keri Martinowich , Stephanie C. Hicks

Test-time adaptation (TTA) intends to adapt the pretrained model to test distributions with only unlabeled test data streams. Most of the previous TTA methods have achieved great success on simple test data streams such as independently…

Computer Vision and Pattern Recognition · Computer Science 2023-03-27 Longhui Yuan , Binhui Xie , Shuang Li

Large language models (LLMs) have shown remarkable reasoning capabilities, yet aligning such abilities to small language models (SLMs) remains a challenge due to distributional mismatches and limited model capacity. Existing reasoning…

Computation and Language · Computer Science 2025-05-28 Yong Wu , Weihang Pan , Ke Li , Chen Binhui , Ping Li , Binbin Lin

Self-supervised learning (SSL), especially contrastive methods, has raised attraction recently as it learns effective transferable representations without semantic annotations. A common practice for self-supervised pre-training is to use as…

Computer Vision and Pattern Recognition · Computer Science 2022-05-27 Zhili Liu , Jianhua Han , Lanqing Hong , Hang Xu , Kai Chen , Chunjing Xu , Zhenguo Li

Online experiments in internet systems, also known as A/B tests, are used for a wide range of system tuning problems, such as optimizing recommender system ranking policies and learning adaptive streaming controllers. Decision-makers…

Machine Learning · Computer Science 2025-07-01 Qing Feng , Samuel Daulton , Benjamin Letham , Maximilian Balandat , Eytan Bakshy

Sparse residual tree (SRT) is an adaptive exploration method for multivariate scattered data approximation. It leads to sparse and stable approximations in areas where the data is sufficient or redundant, and points out the possible local…

Numerical Analysis · Mathematics 2019-05-15 Xin Xu , Xiaopeng Luo

Sequential monitoring of randomized trials traditionally relies on parametric assumptions or asymptotic approximations. We discuss a family of nonparametric sequential tests - collectively called e-RT - for binary, event-only, and…

Methodology · Statistics 2026-05-12 Fernando G Zampieri

We present Speculative Rollout with Tree-Structured Cache (SRT), a simple, model-free approach to accelerate on-policy reinforcement learning (RL) for language models without sacrificing distributional correctness. SRT exploits the…

Machine Learning · Computer Science 2026-01-15 Chi-Chih Chang , Siqi Zhu , Zhichen Zeng , Haibin Lin , Jiaxuan You , Mohamed S. Abdelfattah , Ziheng Jiang , Xuehai Qian

Clustering and dependence are common in trials. For example, in some cluster randomized trials (CRTs), pre-existing clusters are enrolled, randomized, and serve as the basis of intervention delivery. Such CRTs are "fully clustered":…

Sequential Multiple-Assignment Randomized Trials (SMARTs) play an increasingly important role in psychological and behavioral health research. This experimental approach enables researchers to answer scientific questions about how to…

Methodology · Statistics 2023-06-21 John J. Dziak , Daniel Almirall , Walter Dempsey , Catherine Stanger , Inbal Nahum-Shani

In recent years, significant progress has been made in the field of robotic reinforcement learning (RL), enabling methods that handle complex image observations, train in the real world, and incorporate auxiliary data, such as…

Both cluster randomized trials and quasi-experimental designs are used to evaluate the impact of health and social policies and interventions. Stepped-wedge cluster randomized trials randomize a staggered adoption approach, while recent…

Methodology · Statistics 2026-04-15 Haidong Lu , Gregg S. Gonsalves , Fan Li , Guanyu Tong , Lee Kennedy-Shaffer

Many e-learning platforms assert their ability or potential to improve students' self-regulated learning (SRL), however the cyclical and undirected nature of SRL theoretical models represent significant challenges for representation within…

Computers and Society · Computer Science 2025-07-08 Andrew Schwabe , Özgür Akgün , Ella Haig
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