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X-ray free electron lasers (XFEL) create femtosecond X-ray pulses with high brightness and high longitudinal coherence allowing to extend X-ray spectroscopy and scattering techniques into the ultrafast time-domain. These X-rays are a…

Fluorescence imaging is an essential diagnostic tool in many fields, but diffraction-limited optical imaging at depth is limited by scattering. Here, we present a method based on multiple random illuminations, combined with a computational…

Optics · Physics 2026-03-30 Lei Zhu , Tengfei Wu , Bernhard Rauer , Hilton B. de Aguiar , Sylvain Gigan

Efficient simulation of photon registrations in single-photon LiDAR (SPL) is essential for applications such as depth estimation under high-flux conditions, where hardware dead time significantly distorts photon measurements. However, the…

Signal Processing · Electrical Eng. & Systems 2025-06-02 Weijian Zhang , Hashan K. Weerasooriya , Stanley Chan

The first experimental data from single-particle scattering experiments from free electron lasers (FELs) are now becoming available. The first such experiments are being performed on relatively large objects such as viruses, which produce…

Biomolecules · Quantitative Biology 2015-05-28 Dilano Saldin , Hin-Cheuck Poon , Peter Schwander , Miraj Uddin , Marius Schmidt

Fourier Transform Interferometry (FTI) is an interferometric procedure for acquiring HyperSpectral (HS) data. Recently, it has been observed that the light source highlighting a (biologic) sample can be coded before the FTI acquisition in a…

Information Theory · Computer Science 2018-03-09 Amirafshar Moshtaghpour , Laurent Jacques

A Monte Carlo program based on a three dimensional vector approach was developed to model multiple refractive scattering of X-ray photons in objects with a fine structure. A particular interest was paid to the investigation of lung tissue.…

Medical Physics · Physics 2010-02-02 Anastasiya Khromova

Scanning tunneling microscopy (STM) is a powerful technique for imaging atomic structure and inferring information on local elemental composition, chemical bonding, and electronic excitations. However, traditional methods of visual…

Superconductivity · Physics 2023-02-21 Qiang Zou , Basu Dev Oli , Huimin Zhang , Joseph Benigno , Xin Li , Lian Li

Ultrafast diffraction imaging is a powerful tool to retrieve the geometric structure of gas-phase molecules with combined picometre spatial and attosecond temporal resolution. However, structural retrieval becomes progressively difficult…

Chemical Physics · Physics 2021-10-13 Xinyao Liu , Kasra Amini , Aurelien Sanchez , Blanca Belsa , Tobias Steinle , Jens Biegert

Information on the spectral types of stars is of great interest in view of the exploitation of space-based imaging surveys. In this article, we investigate the classification of stars into spectral types using only the shape of their…

Instrumentation and Methods for Astrophysics · Physics 2016-06-15 T. Kuntzer , M. Tewes , F. Courbin

Complex-field imaging is indispensable for numerous applications at wavelengths from X-ray to THz, with amplitude describing transmittance (or reflectivity) and phase revealing intrinsic structure of the target object. Coherent diffraction…

Image and Video Processing · Electrical Eng. & Systems 2021-04-07 Meng Li , Liheng Bian , Guoan Zheng , Andrew Maiden , Yang Liu , Yiming Li , Qionghai Dai , Jun Zhang

The automatic classification of X-ray detections is a necessary step in extracting astrophysical information from compiled catalogs of astrophysical sources. Classification is useful for the study of individual objects, statistics for…

Instrumentation and Methods for Astrophysics · Physics 2024-01-30 Víctor Samuel Pérez-Díaz , Juan Rafael Martínez-Galarza , Alexander Caicedo , Raffaele D'Abrusco

Here we propose to exploit the low energy bandwidth, small wavelength and penetration power of ultrashort pulses from XFELs for resonant Small Angle Scattering (SAXS) on plasma structures in laser excited plasmas. Small angle scattering…

Plasma Physics · Physics 2016-03-09 Thomas Kluge , M. Bussmann , H. -K. Chung , C. Gutt , L. G. Huang , M. Zacharias , U. Schramm , T. E. Cowan

Super-resolution fluorescence microscopy, with a resolution beyond the diffraction limit of light, has become an indispensable tool to directly visualize biological structures in living cells at a nanometer-scale resolution. Despite…

Computer Vision and Pattern Recognition · Computer Science 2018-09-05 Yu Li , Fan Xu , Fa Zhang , Pingyong Xu , Mingshu Zhang , Ming Fan , Lihua Li , Xin Gao , Renmin Han

We study the local distortion of the atomic structure in small biological samples illuminated by x-ray free electron laser (XFEL) pulses. We concentrate on the effect of inhomogenities: heavy atoms in a light matrix and non-homogeneous…

Atomic and Molecular Clusters · Physics 2015-05-13 Zoltan Jurek , Gyula Faigel

Hyperspectral imaging (HSI) enables detailed land cover classification, yet low spatial resolution and sparse annotations pose significant challenges. We present a label-efficient framework that leverages spatial features from a frozen…

Computer Vision and Pattern Recognition · Computer Science 2025-12-04 Yuzhen Hu , Biplab Banerjee , Saurabh Prasad

X-ray free-electron lasers (XFELs) promise the diffractive imaging of single molecules and nanoparticles with atomic spatial resolution. This relies on the averaging of millions of diffraction patterns of identical particles, which should…

Visual inspection of x-ray scattering images is a powerful technique for probing the physical structure of materials at the molecular scale. In this paper, we explore the use of deep learning to develop methods for automatically analyzing…

Computer Vision and Pattern Recognition · Computer Science 2016-11-11 Boyu Wang , Kevin Yager , Dantong Yu , Minh Hoai

High-speed multiplex imaging of fluorescent probes is limited by a combination of spectral resolution, sensitivity, high cost and low light throughput of detectors, and filters. In this work, we present a hyperspectral detection system…

In this work, we have investigated a number of unsupervised learning methods for material segmentation in projection x-ray imaging with a spectral detector. A phantom containing two hard materials (glass, steel) and three soft materials…