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This paper introduces Spectral Incoherent Diffractive Imaging (SIDI) as a novel method for achieving dark-field imaging of nanostructures with heterogeneous oxidation states. With SIDI, shifts in photoemission profiles can be spatially…

Optics · Physics 2023-12-25 Tamme Wollweber , Kartik Ayyer

X-ray free-electron lasers (XFELs) are the only sources currently able to produce bright few-fs pulses with tunable photon energies from 100 eV to more than 10 keV. Due to the stochastic SASE operating principles and other technical issues…

Single-shot diffraction imaging of isolated nanosized particles has seen remarkable success in recent years, yielding in-situ measurements with ultra-high spatial and temporal resolution. The progress of high-repetition-rate sources for…

Atomic and Molecular Clusters · Physics 2022-08-26 Julian Zimmermann , Fabien Beguet , Daniel Guthruf , Bruno Langbehn , Daniela Rupp

This paper introduces a single-pixel HyperSpectral (HS) imaging framework based on Fourier Transform Interferometry (FTI). By combining a space-time coding of the light illumination with partial interferometric observations of a collimated…

Computer Vision and Pattern Recognition · Computer Science 2018-09-05 Amirafshar Moshtaghpour , José M. Bioucas-Dias , Laurent Jacques

Federated learning (FL) based magnetic resonance (MR) image reconstruction can facilitate learning valuable priors from multi-site institutions without violating patient's privacy for accelerating MR imaging. However, existing methods rely…

Image and Video Processing · Electrical Eng. & Systems 2023-05-11 Juan Zou , Cheng Li , Ruoyou Wu , Tingrui Pei , Hairong Zheng , Shanshan Wang

Molecular fluorescence microscopy is a leading approach to super-resolution and nanoscale imaging in life and material sciences. However, super-resolution fluorescence microscopy is often bottlenecked by system-specific calibrations and…

X-ray free electron lasers (XFELs) generate sequences of ultra-short, spatially coherent pulses of x-ray radiation. We propose the diffraction focusing spectrometer (DFS), which is able to measure the whole energy spectrum of the radiation…

Optics · Physics 2013-02-22 V. G. Kohn , O. Y. Gorobtsov , I. A. Vartanyants

Single-pixel imaging, with the advantages of a wide spectrum, beyond-visual-field imaging, and robustness to light scattering, has attracted increasing attention in recent years. Fourier single-pixel imaging (FSI) can reconstruct sharp…

Image and Video Processing · Electrical Eng. & Systems 2021-08-05 Dong Zhou , Jie Cao , Huan Cui , Qun Hao , Bing-Kun Chen , Kai Lin

X-ray scattering experiments using Free Electron Lasers (XFELs) are a powerful tool to determine the molecular structure and function of unknown samples (such as COVID-19 viral proteins). XFEL experiments are a challenge to computing in two…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-03-21 Johannes P. Blaschke , Aaron S. Brewster , Daniel W. Paley , Derek Mendez , Asmit Bhowmick , Nicholas K. Sauter , Wilko Kröger , Murali Shankar , Bjoern Enders , Deborah Bard

The Linac Coherent Light Source (LCLS) is an X- ray free electron laser (XFEL) facility enabling the study of the structure and dynamics of single macromolecules. A major upgrade will bring the repetition rate of the X-ray source from 120…

Computational Physics · Physics 2021-09-14 Hsing-Yin Chang , Elliott Slaughter , Seema Mirchandaney , Jeffrey Donatelli , Chun Hong Yoon

Fourier single-pixel imaging (FSI) is a branch of single-pixel imaging techniques. It uses Fourier basis patterns as structured patterns for spatial information acquisition in the Fourier domain. However, the spatial resolution of the image…

Image and Video Processing · Electrical Eng. & Systems 2021-08-06 Ziheng Qiu , Xinyi Guo , Tianao Lu , Pan Qi , Zibang Zhang , Jingang Zhong

In this paper we propose a new method for measurements of the longitudinal profile of 100 femtosecond electron bunches for X-ray Free Electron Lasers (XFELs). The method is simply the combination of two well-known techniques, which where…

Accelerator Physics · Physics 2009-11-10 E. L. Saldin , E. A. Schneidmiller , M. V. Yurkov

Machine learning is attracting surging interest across nearly all scientific areas by enabling the analysis of large datasets and the extraction of scientific information from incomplete data. Data-driven science is rapidly growing,…

Applied Physics · Physics 2025-03-17 Sung Yun Lee , Do Hyung Cho , Chulho Jung , Daeho Sung , Daewoong Nam , Sangsoo Kim , Changyong Song

X-ray Absorption Spectroscopy (XAS) is a widely used X-ray diagnostic method. While synchrotrons have large communities of XAS users, its use on X-Ray Free Electron Lasers (XFEL) facilities has been rather limited. At a first glance, the…

Instrumentation and Detectors · Physics 2020-05-05 M. Harmand , M. Cammarata , M. Chollet , A. G Krygier , H. T. Lemke , D. Zhu

The collection and curation of large-scale medical datasets from multiple institutions is essential for training accurate deep learning models, but privacy concerns often hinder data sharing. Federated learning (FL) is a promising solution…

Computer Vision and Pattern Recognition · Computer Science 2023-01-12 Rui Yan , Liangqiong Qu , Qingyue Wei , Shih-Cheng Huang , Liyue Shen , Daniel Rubin , Lei Xing , Yuyin Zhou

Immunofluorescent (IF) imaging is crucial for visualizing biomarker expressions, cell morphology and assessing the effects of drug treatments on sub-cellular components. IF imaging needs extra staining process and often requiring cell…

Coherent diffraction imaging (CDI) using synchrotron radiation, X-ray free electron lasers (X-FELs), high harmonic generation, soft X-ray lasers, and optical lasers has found broad applications across several disciplines. An active research…

X-ray single particle imaging involves the measurement of a large number of noisy diffraction patterns of isolated objects in random orientations. The missing information about these patterns is then computationally recovered in order to…

Image and Video Processing · Electrical Eng. & Systems 2020-05-25 Kartik Ayyer

The advent of isolated and intense sub-femtosecond X-ray pulses enables tracking of quantummechanical motion of electrons in molecules and solids. The combination of X-ray spectroscopy and diffraction imaging is a powerful approach to…

Imaging the structure and observing the dynamics of isolated proteins using single-particle X-ray diffractive imaging (SPI) is one of the potential applications of X-ray free-electron lasers (XFELs). Currently, SPI experiments on isolated…