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How self-organized networks develop, mature and degenerate is a key question for sociotechnical, cyberphysical and biological systems with potential applications from tackling violent extremism through to neurological diseases. So far, it…

Physics and Society · Physics 2017-06-05 M. Zheng , Z. Cao , Y. Vorobyeva , P. Manrique , C. Song , N. F. Johnson

We use a discrete-time proportional hazards model of time to involuntary employment termination. This model enables us to examine both the continuous effect of the age of an employee and whether that effect has varied over time,…

Applications · Statistics 2010-11-15 George Woodworth , Joseph Kadane

Many existing mortality models follow the framework of classical factor models, such as the Lee-Carter model and its variants. Latent common factors in factor models are defined as time-related mortality indices (such as $\kappa_t$ in the…

Methodology · Statistics 2021-02-04 Lingyu He , Fei Huang , Jianjie Shi , Yanrong Yang

The viral load of patients infected with SARS-CoV-2 varies on logarithmic scales and possibly with age. Controversial claims have been made in the literature regarding whether the viral load distribution actually depends on the age of the…

Joinpoint regression is used to determine the number of segments needed to adequately explain the relationship between two variables. This methodology can be widely applied to real problems, but we focus on epidemiological data, the main…

Applications · Statistics 2011-12-08 Miguel A. Martinez-Beneito , Gonzalo García-Donato , Diego Salmerón

Multi-dimensional functional data arises in numerous modern scientific experimental and observational studies. In this paper we focus on longitudinal functional data, a structured form of multidimensional functional data. Operating within a…

Methodology · Statistics 2019-09-20 John Shamshoian , Damla Senturk , Shafali Jeste , Donatello Telesca

Separate modelling of cause specific mortality rates and their projections can yield inconsistent forecasts when the sum of deaths by cause does not match the total observed in a population. We develop a hierarchical probabilistic framework…

Applications · Statistics 2026-03-03 Andrea Nigri , Han Lin Shang , Francesco Ungolo

To this day, terrorism persists as a worldwide threat, as exemplified by the ongoing lethal attacks perpetrated by ISIS in Iraq, Syria, Al Qaeda in Yemen, and Boko Haram in Nigeria. In response, states deploy various counterterrorism…

Applications · Statistics 2016-10-12 André Python , Janine Illian , Charlotte Jones-Todd , Marta Blangiardo

This paper generalizes a previously published differential equation that describes the relation between the age-specific incidence, remission, and mortality of a disease with its prevalence. The underlying model is a simple compartment…

Populations and Evolution · Quantitative Biology 2012-09-07 Ralph Brinks

Analyzing demographic data collected across multiple populations, time periods, and age groups is challenging due to the interplay of high dimensionality, demographic heterogeneity among groups, and stochastic variability within smaller…

Applications · Statistics 2025-12-12 Gregor Zens

Dynamics of the infectious disease transmission is often best understood taking into account the structure of population with respect to specific features, in example age or immunity level. Practical utility of such models depends on the…

Applications · Statistics 2016-06-21 Piotr Gwiazda , Błażej Miasojedow , Magdalena Rosińska

In epidemiological studies of air pollution and public health, estimating the health impact of exposure to air pollution may be hindered by the unknown functional form of the exposure-outcome association and by unmeasured confounding…

Methodology · Statistics 2026-01-28 Carlo Zaccardi , Pasquale Valentini , Luigi Ippoliti , Alexandra M. Schmidt

In this article we investigate a state-space representation of the Lee-Carter model which is a benchmark stochastic mortality model for forecasting age-specific death rates. Existing relevant literature focuses mainly on mortality…

Computational Finance · Quantitative Finance 2015-08-04 Man Chung Fung , Gareth W. Peters , Pavel V. Shevchenko

Ignoring the differences between countries, human reproductive and dispersal behaviors can be described by some standardized models, so whether there is a universal law of population growth hidden in the abundant and unstructured data from…

Physics and Society · Physics 2024-02-08 Jiajun Ma , Qinghua Chen , Xiaosong Chen , Jingfang Fan , Xiaomeng Li , Yi Shi

Aging is a multidimensional process where phenotypes change at varying rates. Longitudinal studies of aging typically involve following a cohort of individuals over the course of several years. This design is hindered by cost, attrition,…

Spatial scan statistics are well known and widely used methods for the detection of spatial clusters of events. In the field of spatial analysis of time-to-event data, several models of scan statistics have been proposed. However, these…

Methodology · Statistics 2022-09-02 Camille Frévent , Mohamed-Salem Ahmed , Sophie Dabo-Niang , Michaël Genin

Simulating the population dynamics of a stage-structured population requires the knowledge of the biodemographic functions characterizing the species, namely development, mortality and fecundity. In general, development and fecundity can…

Populations and Evolution · Quantitative Biology 2020-10-27 Sara Pasquali , Cinzia Soresina , Enrico Marchesini

As cancer patient survival improves, late effects from treatment are becoming the next clinical challenge. Chemotherapy and radiotherapy, for example, potentially increase the risk of both morbidity and mortality from second malignancies…

Smoking is one of the main risk factors that has affected human mortality and life expectancy over the past century. Smoking accounts for a large part of the nonlinearities in the growth of life expectancy and of the geographic and sex…

Applications · Statistics 2019-10-29 Yicheng Li , Adrian E. Raftery

Joint models for longitudinal and time-to-event data have seen many developments in recent years. Though spatial joint models are still rare and the traditional proportional hazards formulation of the time-to-event part of the model is…

Methodology · Statistics 2024-06-25 Anja Rappl , Thomas Kneib , Stefan Lang , Elisabeth Bergherr