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Aggregated health data such as claims data from health insurances become more and more available for research purposes. Estimates of excess mortality from prevalence and incidence of a chronic condition have only been possible for ages 50…

Populations and Evolution · Quantitative Biology 2019-08-13 Ralph Brinks

We investigate the decline of infant mortality in 42 low and middle income countries (LMIC) using detailed micro data from 84 Demographic and Health Surveys. We estimate infant mortality risk for each infant in our data and develop a novel…

Applications · Statistics 2020-09-14 Antonio P. Ramos , Martin J. Flores , Leiwen Gao , Patrick Heuveline , Robert E. Weiss

A robust multilevel functional data method is proposed to forecast age-specific mortality rate and life expectancy for two or more populations in developed countries with high-quality vital registration systems. It uses a robust multilevel…

Applications · Statistics 2016-09-27 Han Lin Shang

Multivariate functional data that are cross-sectionally compositional data are attracting increasing interest in the statistical modeling literature, a major example being trajectories over time of compositions derived from cause-specific…

Methodology · Statistics 2023-11-21 Emanuele Giovanni Depaoli , Marco Stefanucci , Stefano Mazzuco

In most cases, mortality is analysed considering summary indicators (e.~g. $e_0$ or $e^{\dagger}_0$) that either focus on a specific mortality component or pool all component-specific information in one measure. This can be a limitation,…

Applications · Statistics 2022-06-16 Ainhoa-Elena Léger , Stefano Mazzuco

The COVID-19 infection fatality rate (IFR) is the proportion of individuals infected with SARS-CoV-2 who subsequently die. As COVID-19 disproportionately affects older individuals, age-specific IFR estimates are imperative to facilitate…

Cause-of-death data is fundamental for understanding population health trends and inequalities as well as designing and evaluating public health interventions. A significant proportion of global deaths, particularly in low- and…

Applications · Statistics 2025-02-04 Yu Zhu , Zehang Richard Li

Worldwide, many millions of people die suddenly and unexpectedly each year, either with or without a prior history of cardiovascular disease. Such events are sparse (once in a lifetime), many victims will not have had prior investigations…

Machine Learning · Computer Science 2023-09-06 Yola Jones , Fani Deligianni , Jeff Dalton , Pierpaolo Pellicori , John G F Cleland

Accurate forecasts of weekly mortality are essential for public health and the insurance industry. We develop a forecasting framework that extends the Lee-Carter model with age- and region-specific seasonal effects and penalized distributed…

Applications · Statistics 2026-05-22 Jens Robben , Karim Barigou

To explore the mechanistic relationships between ageing, frailty and mortality, we developed a computational model in which possible health attributes are represented by the nodes of a complex network. Each node can be either damaged (i.e.…

Populations and Evolution · Quantitative Biology 2017-06-30 Andrew D. Rutenberg , Arnold B. Mitnitski , Spencer Farrell , Kenneth Rockwood

A multiple objective space-time forecasting approach is presented involving cyclical curve log-regression, and multivariate time series spatial residual correlation analysis. Specifically, the mean quadratic loss function is minimized in…

Machine Learning · Statistics 2021-03-30 A. Torres-Signes , M. P. Frías , M. D. Ruiz-Medina

The EU Solvency II directive recommends insurance companies to pay more attention to the risk management methods. The sense of risk management is the ability to quantify risk and apply methods that reduce uncertainty. In life insurance, the…

Econometrics · Economics 2018-04-02 Kamil Jodź

To better understand mortality change with age capturing the variability in individuals' rates of aging, we performed comprehensive analysis of statistical properties of a cumulative index of age-associated disorders (deficits), called a…

Populations and Evolution · Quantitative Biology 2007-05-23 A. Kulminski , A. Yashin , I. Akushevich , S. Ukraintseva , K. Land , K. Arbeev , K. Manton

This paper extends the Lee-Carter model for single- and multi-populations to account for pandemic jump effects of vanishing kind, allowing for a more comprehensive and accurate representation of mortality rates during a pandemic,…

Applications · Statistics 2024-08-30 Julius Goes , Karim Barigou , Anne Leucht

Reducing the global burden of stillbirths is important to improving child and maternal health. Of interest is understanding patterns in the timing of stillbirths -- that is, whether they occur in the intra- or antepartum period -- because…

Applications · Statistics 2022-12-14 Michael Y. C. Chong , Monica Alexander

We propose a series of methods and models in order to explore the Global Burden of Disease Study and the provided healthy life expectancy HALE estimates from the World Health Organization WHO based on the mortality mx of a population…

Populations and Evolution · Quantitative Biology 2016-03-09 Christos H Skiadas

Bayesian networks (BNs) are graphical models that are useful for representing high-dimensional probability distributions. There has been a great deal of interest in recent years in the NP-hard problem of learning the structure of a BN from…

Machine Learning · Statistics 2016-10-04 D. Jennings , J. N. Corcoran

Mortality forecasting is crucial for demographic planning and actuarial studies, especially for projecting population ageing and longevity risk. Classical approaches largely rely on extrapolative methods, such as the Lee-Carter (LC) model,…

Applications · Statistics 2026-02-24 Han Ying Lim , Dharini Pathmanathan , Sophie Dabo-Niang

In the initial wave of the COVID-19 pandemic we observed great discrepancies in both infection and mortality rates between countries. Besides the biological and epidemiological factors, a multitude of social and economic criteria also…

Physics and Society · Physics 2022-01-14 Viktor Stojkoski , Zoran Utkovski , Petar Jolakoski , Dragan Tevdovski , Ljupco Kocarev

Mortality data are relevant to demography, public health, and actuarial science. Whilst clustering is increasingly used to explore patterns in such data, no study has reviewed its application to country-level all-cause mortality. This…

Applications · Statistics 2025-12-05 Pedro Menezes de Araujo , Isobel Claire Gormley , Thomas Brendan Murphy
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