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Phase contrast transmission electron microscopy (TEM) is a powerful tool for imaging the local atomic structure of materials. TEM has been used heavily in studies of defect structures of 2D materials such as monolayer graphene due to its…

Materials Science · Physics 2021-09-01 Robbie Sadre , Colin Ophus , Anstasiia Butko , Gunther H Weber

Deployment of machine learning algorithms into real-world practice is still a difficult task. One of the challenges lies in the unpredictable variability of input data, which may differ significantly among individual users, institutions,…

Computer Vision and Pattern Recognition · Computer Science 2024-11-26 Roman Stoklasa

Single-particle cryo-electron microscopy (cryo-EM) has become a cornerstone of structural biology, enabling near-atomic resolution analysis of macromolecules through advanced computational methods. However, the development of cryo-EM…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Runmin Jiang , Genpei Zhang , Yuntian Yang , Siqi Wu , Minhao Wu , Wanyue Feng , Yizhou Zhao , Xi Xiao , Xiao Wang , Tianyang Wang , Xingjian Li , Muyuan Chen , Min Xu

The transformer based model (e.g., FusingTF) has been employed recently for Electrocardiogram (ECG) signal classification. However, the high-dimensional embedding obtained via 1-D convolution and positional encoding can lead to the loss of…

Signal Processing · Electrical Eng. & Systems 2021-04-01 Jian Guan , Wenbo Wang , Pengming Feng , Xinxin Wang , Wenwu Wang

Cryogenic electron tomography is a technique for imaging biological samples in 3D. A microscope collects a series of 2D projections of the sample, and the goal is to reconstruct the 3D density of the sample called the tomogram.…

Computer Vision and Pattern Recognition · Computer Science 2024-08-13 Simon Wiedemann , Reinhard Heckel

We target the problem of estimating the center of mass of noisy 2-D images. We assume that the noise dominates the image, and thus many standard approaches are vulnerable to estimation errors. Our approach uses a surrogate function to the…

Image and Video Processing · Electrical Eng. & Systems 2021-03-04 Ayelet Heimowitz , Nir Sharon , Amit Singer

Finding a template in a search image is an important task underlying many computer vision applications. Recent approaches perform template matching in a deep feature-space, produced by a convolutional neural network (CNN), which is found to…

Computer Vision and Pattern Recognition · Computer Science 2021-05-10 Bo Gao , M. W. Spratling

Cellular processes are governed by macromolecular complexes inside the cell. Study of the native structures of macromolecular complexes has been extremely difficult due to lack of data. With recent breakthroughs in Cellular electron cryo…

Quantitative Methods · Quantitative Biology 2018-06-12 Chengqian Che , Ruogu Lin , Xiangrui Zeng , Karim Elmaaroufi , John Galeotti , Min Xu

Local feature extraction is a standard approach in computer vision for tackling important tasks such as image matching and retrieval. The core assumption of most methods is that images undergo affine transformations, disregarding more…

Computer Vision and Pattern Recognition · Computer Science 2023-04-04 Guilherme Potje , Felipe Cadar , Andre Araujo , Renato Martins , Erickson R. Nascimento

Cryo Focused Ion-Beam Scanning Electron Microscopy (cryo FIB-SEM) enables three-dimensional and nanoscale imaging of biological specimens via a slice and view mechanism. The FIB-SEM experiments are, however, limited by a slow (typically,…

We report the development of a combined machine-learning and high-throughput density functional theory (DFT) framework to accelerate the search for new ferroelectric materials. The framework can predict potential ferroelectric compounds…

A major challenge in single particle reconstruction methods using cryo-electron microscopy is to attain a resolution sufficient to interpret fine details in three-dimensional (3D) macromolecular structures. Obtaining high resolution 3D…

Numerical Analysis · Mathematics 2013-07-23 Lanhui Wang , Yoel Shkolnisky , Amit Singer

In this work, we address the limitations of denoising diffusion models (DDMs) in image restoration tasks, particularly the shape and color distortions that can compromise image quality. While DDMs have demonstrated a promising performance…

Computer Vision and Pattern Recognition · Computer Science 2024-12-18 Xinlong Cheng , Tiantian Cao , Guoan Cheng , Bangxuan Huang , Xinghan Tian , Ye Wang , Xiaoyu He , Weixin Li , Tianfan Xue , Xuan Dong

Atomic resolution electron microscopy, particularly high-angle annular dark-field scanning transmission electron microscopy, has become an essential tool for many scientific fields, when direct visualization of atomic arrangements and…

Understanding many processes, e.g. fusion experiments, planetary interiors and dwarf stars, depends strongly on microscopic physics modeling of warm dense matter (WDM) and hot dense plasma. This complex state of matter consists of a…

Computational Physics · Physics 2020-08-05 Alexander J. White , Lee A. Collins

We aim to provide a general framework of for computational photography that recovers the real scene from imperfect images, via the Deep Nonparametric Convexified Filtering (DNCF). It is consists of a nonparametric deep network to resemble…

Computer Vision and Pattern Recognition · Computer Science 2023-09-15 Jianqiao Wangni

Operando microscopy provides direct insight into the dynamic chemical and physical processes that govern functional materials, yet measurement noise limits the effective resolution and undermines quantitative analysis. Here, we present a…

Computer Vision and Pattern Recognition · Computer Science 2025-11-03 Samuel Degnan-Morgenstern , Alexander E. Cohen , Rajeev Gopal , Megan Gober , George J. Nelson , Peng Bai , Martin Z. Bazant

Intrinsic image decomposition is an important and long-standing computer vision problem. Given an input image, recovering the physical scene properties is ill-posed. Several physically motivated priors have been used to restrict the…

Computer Vision and Pattern Recognition · Computer Science 2022-09-27 Zongji Wang , Yunfei Liu , Feng Lu

We propose Deep Feature Factorization (DFF), a method capable of localizing similar semantic concepts within an image or a set of images. We use DFF to gain insight into a deep convolutional neural network's learned features, where we…

Machine Learning · Computer Science 2018-10-09 Edo Collins , Radhakrishna Achanta , Sabine Süsstrunk

We propose a new microscopy simulation system that can depict atomistic models in a micrograph visual style, similar to results of physical electron microscopy imaging. This system is scalable, able to represent simulation of electron…

Quantitative Methods · Quantitative Biology 2026-03-27 Ngan Nguyen , Feng Liang , Dominik Engel , Ciril Bohak , Peter Wonka , Timo Ropinski , Ivan Viola