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Electron cryo-microscopy (cryo-EM) produces three-dimensional (3D) maps of the electrostatic potential of biological macromolecules, including proteins. Along with knowledge about the imaged molecules, cryo-EM maps allow de novo atomic…

Quantitative Methods · Quantitative Biology 2023-02-09 Kiarash Jamali , Dari Kimanius , Sjors H. W. Scheres

The living body is composed of innumerable fine and complex structures and although these structures have been studied in the past, a vast amount of information pertaining to them still remains unknown. When attempting to observe these…

Medical Physics · Physics 2021-11-30 Raku Son , Kenji Yamazawa , Akiko Oguchi , Mitsuo Suga , Masaru Tamura , Yasuhiro Murakawa , Satoshi Kume

We introduce ICE-TIDE, a method for cryogenic electron tomography (cryo-ET) that simultaneously aligns observations and reconstructs a high-resolution volume. The alignment of tilt series in cryo-ET is a major problem limiting the…

Image and Video Processing · Electrical Eng. & Systems 2024-12-16 Valentin Debarnot , Vinith Kishore , Ricardo D. Righetto , Ivan Dokmanić

High-resolution transmission electron microscopy (HRTEM) is crucial for observing material's structural and morphological evolution at Angstrom scales, but the electron beam can alter these processes. Devices such as CMOS-based…

Materials Science · Physics 2025-12-04 Brian Lee , Meng Li , Judith C Yang , Dmitri N Zakharov , Xiaohui Qu

CT images corrupted by metal artifacts have serious negative effects on clinical diagnosis. Considering the difficulty of collecting paired data with ground truth in clinical settings, unsupervised methods for metal artifact reduction are…

Computer Vision and Pattern Recognition · Computer Science 2023-07-31 Wangduo Xie , Matthew B. Blaschko

In this paper, we demonstrate a computationally efficient new approach based on deep learning (DL) techniques for analysis, design, and optimization of electromagnetic (EM) nanostructures. We use the strong correlation among features of a…

Machine Learning · Computer Science 2020-02-13 Yashar Kiarashinejad , Sajjad Abdollahramezani , Ali Adibi

Traditional image acquisition for cryo focused ion-beam scanning electron microscopy tomography often sees thousands of images being captured over a period of many hours, with immense data sets being produced. When imaging beam sensitive…

Image acquisition conditions and environments can significantly affect high-level tasks in computer vision, and the performance of most computer vision algorithms will be limited when trained on distortion-free datasets. Even with updates…

Computer Vision and Pattern Recognition · Computer Science 2023-09-27 Boyuan Ji , Jianchang Huang , Wenzhuo Huang , Shuke He

While zero-shot diffusion-based compression methods have seen significant progress in recent years, they remain notoriously slow and computationally demanding. This paper presents an efficient zero-shot diffusion-based compression method…

Image and Video Processing · Electrical Eng. & Systems 2026-04-15 Amit Vaisman , Guy Ohayon , Hila Manor , Michael Elad , Tomer Michaeli

The goal of cryo-electron microscopy (EM) is to reconstruct the 3-dimensional structure of a molecule from a collection of its 2-dimensional projected images. In this article, we show that the basic premise of cryo-EM --- patching together…

Computer Vision and Pattern Recognition · Computer Science 2017-04-25 Ke Ye , Lek-Heng Lim

Techniques for dense semantic correspondence have provided limited ability to deal with the geometric variations that commonly exist between semantically similar images. While variations due to scale and rotation have been examined, there…

Computer Vision and Pattern Recognition · Computer Science 2017-07-19 Seungryong Kim , Dongbo Min , Stephen Lin , Kwanghoon Sohn

Deep convolutional Neural Networks (CNN) are the state-of-the-art performers for object detection task. It is well known that object detection requires more computation and memory than image classification. Thus the consolidation of a…

Computer Vision and Pattern Recognition · Computer Science 2017-05-18 Subarna Tripathi , Gokce Dane , Byeongkeun Kang , Vasudev Bhaskaran , Truong Nguyen

Single-particle cryo-electron microscopy (cryo-EM) is a leading technology to resolve the structure of molecules. Early in the process, the user detects potential particle images in the raw data. Typically, there are many false detections…

Image and Video Processing · Electrical Eng. & Systems 2023-03-08 Gili Weiss-Dicker , Amitay Eldar , Yoel Shkolinsky , Tamir Bendory

Cryo-Electron Tomography (Cryo-ET) enables detailed 3D visualization of cellular structures in near-native states but suffers from low signal-to-noise ratio due to imaging constraints. Traditional denoising methods and supervised learning…

Image and Video Processing · Electrical Eng. & Systems 2025-02-25 Xiwei Liu , Mohamad Kassab , Min Xu , Qirong Ho

Scanning transmission electron microscopy (STEM) is a powerful tool to reveal the morphologies and structures of materials, thereby attracting intensive interests from the scientific and industrial communities. The outstanding spatial…

Image and Video Processing · Electrical Eng. & Systems 2024-09-26 Hanlei Zhang , Jincheng Bai , Xiabo Chen , Can Li , Chuanjian Zhong , Jiye Fang , Guangwen Zhou

Discriminative Correlation Filter (DCF) based methods have shown competitive performance on tracking benchmarks in recent years. Generally, DCF based trackers learn a rigid appearance model of the target. However, this reliance on a single…

Computer Vision and Pattern Recognition · Computer Science 2017-06-12 Joakim Johnander , Martin Danelljan , Fahad Shahbaz Khan , Michael Felsberg

We propose an adaptive learning procedure to learn patch-based image priors for image denoising. The new algorithm, called the Expectation-Maximization (EM) adaptation, takes a generic prior learned from a generic external database and…

Computer Vision and Pattern Recognition · Computer Science 2016-08-24 Enming Luo , Stanley H. Chan , Truong Q. Nguyen

Brain tumor classification from magnetic resonance imaging, which is also known as MRI, plays a sensitive role in computer-assisted diagnosis systems. In recent years, deep learning models have achieved high classification accuracy.…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Hiba Adil Al-kharsan , Róbert Rajkó

Deep learning has emerged as the predominant solution for classifying medical images. We intend to apply these developments to the ultra-widefield (UWF) retinal imaging dataset. Since UWF images can accurately diagnose various retina…

Image and Video Processing · Electrical Eng. & Systems 2025-03-25 Siwon Kim , Wooyung Yun , Jeongbin Oh , Soomok Lee

Electron cryotomography (CryoET) is currently the only method capable of visualizing cells in 3D at nanometer resolutions. While modern instruments produce massive amounts of tomography data containing extremely rich structural information,…

Quantitative Methods · Quantitative Biology 2021-07-01 Muyuan Chen , James M. Bell , Xiaodong Shi , Stella Y. Sun , Zhao Wang , Steven J. Ludtke
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