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Fully convolutional deep neural networks carry out excellent potential for fast and accurate image segmentation. One of the main challenges in training these networks is data imbalance, which is particularly problematic in medical imaging…

Computer Vision and Pattern Recognition · Computer Science 2017-06-20 Seyed Sadegh Mohseni Salehi , Deniz Erdogmus , Ali Gholipour

Automatic segmentation methods are an important advancement in medical image analysis. Machine learning techniques, and deep neural networks in particular, are the state-of-the-art for most medical image segmentation tasks. Issues with…

Image and Video Processing · Electrical Eng. & Systems 2021-11-25 Michael Yeung , Evis Sala , Carola-Bibiane Schönlieb , Leonardo Rundo

The retinal vessel network studied through fundus images contributes to the diagnosis of multiple diseases not only found in the eye. The segmentation of this system may help the specialized task of analyzing these images by assisting in…

Image and Video Processing · Electrical Eng. & Systems 2022-06-02 Daniela Herrera , Gilberto Ochoa-Ruiz , Miguel Gonzalez-Mendoza , Christian Mata

Traditional loss functions in medical image segmentation, such as Dice, often under-segment small lesions because their small relative volume contributes negligibly to the overall loss. To address this, instance-wise loss functions and…

Computer Vision and Pattern Recognition · Computer Science 2026-04-08 Luc Bouteille , Alexander Jaus , Jens Kleesiek , Rainer Stiefelhagen , Lukas Heine

Target imbalance affects the performance of recent deep learning methods in many medical image segmentation tasks. It is a twofold problem: class imbalance - positive class (lesion) size compared to negative class (non-lesion) size; lesion…

Image and Video Processing · Electrical Eng. & Systems 2020-07-21 Boris Shirokikh , Alexey Shevtsov , Anvar Kurmukov , Alexandra Dalechina , Egor Krivov , Valery Kostjuchenko , Andrey Golanov , Mikhail Belyaev

Fully convolutional deep neural networks have been asserted to be fast and precise frameworks with great potential in image segmentation. One of the major challenges in training such networks raises when data is unbalanced, which is common…

Computer Vision and Pattern Recognition · Computer Science 2018-12-17 Seyed Raein Hashemi , Seyed Sadegh Mohseni Salehi , Deniz Erdogmus , Sanjay P. Prabhu , Simon K. Warfield , Ali Gholipour

Segmentation of Hypoxic-Ischemic Encephalopathy (HIE) lesions in neonatal MRI is a crucial but challenging task due to diffuse multifocal lesions with varying volumes and the limited availability of annotated HIE lesion datasets. Using the…

Computer Vision and Pattern Recognition · Computer Science 2025-02-14 Annayah Usman , Abdul Haseeb , Tahir Syed

Accurate brain image segmentation, particularly for distinguishing various tissues from magnetic resonance imaging (MRI) images, plays a pivotal role in finding the neurological dis ease and medical image computing. In deep learning…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Hanuman Verma , Akshansh Gupta , Pranabesh Maji , Saurav Mandal , Vijay Kumar Pandey

Brain tumor segmentation is crucial for diagnosis and treatment planning, yet challenges such as class imbalance and limited model generalization continue to hinder progress. This work presents a reproducible evaluation of U-Net…

Computer Vision and Pattern Recognition · Computer Science 2025-10-13 Saumya B

The ability to extrapolate gene expression dynamics in living single cells requires robust cell segmentation, and one of the challenges is the amorphous or irregularly shaped cell boundaries. To address this issue, we modified the U-Net…

Quantitative Methods · Quantitative Biology 2020-01-17 Nanyan Zhu , Chen Liu , Zakary S. Singer , Tal Danino , Andrew F. Laine , Jia Guo

Incorporating modern computer vision techniques into clinical protocols shows promise in improving skin lesion segmentation. The U-Net architecture has been a key model in this area, iteratively improved to address challenges arising from…

Image and Video Processing · Electrical Eng. & Systems 2025-03-31 Tariq M Khan , Dawn Lin , Shahzaib Iqbal , Erik Meijering

This paper presents a new robust loss function, the T-Loss, for medical image segmentation. The proposed loss is based on the negative log-likelihood of the Student-t distribution and can effectively handle outliers in the data by…

Computer Vision and Pattern Recognition · Computer Science 2023-06-02 Alvaro Gonzalez-Jimenez , Simone Lionetti , Philippe Gottfrois , Fabian Gröger , Marc Pouly , Alexander Navarini

Automated segmentation of cancerous lesions in PET/CT images is a vital initial task for quantitative analysis. However, it is often challenging to train deep learning-based segmentation methods to high degree of accuracy due to the…

Image and Video Processing · Electrical Eng. & Systems 2023-09-26 Shadab Ahamed , Arman Rahmim

Many loss functions have been derived from cross-entropy loss functions such as large-margin softmax loss and focal loss. The large-margin softmax loss makes the classification more rigorous and prevents overfitting. The focal loss…

Computer Vision and Pattern Recognition · Computer Science 2023-02-10 Jiajie Chen

We propose a unified objective function, termed CATMIL, that augments the base segmentation loss with two auxiliary supervision terms operating at different levels. The first term, Component-Adaptive Tversky, reweights voxel contributions…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Minh Sao Khue Luu , Evgeniy N. Pavlovskiy , Bair N. Tuchinov

Since the beginning of this decade, CNN has been a very successful tool in the field of Computer Vision tasks.The invention of CNN was inspired from neuroscience and it shares a lot of anatomical similarities with our visual system.Inspired…

Image and Video Processing · Electrical Eng. & Systems 2020-10-12 Kaushik Das , Qianni Zhang

Medical image segmentation is a critical process in the field of medical imaging, playing a pivotal role in diagnosis, treatment, and research. It involves partitioning of an image into multiple regions, representing distinct anatomical or…

Computer Vision and Pattern Recognition · Computer Science 2024-12-03 Charulkumar Chodvadiya , Navyansh Mahla , Kinshuk Gaurav Singh , Kshitij Sharad Jadhav

Segmentation for tracking surgical instruments plays an important role in robot-assisted surgery. Segmentation of surgical instruments contributes to capturing accurate spatial information for tracking. In this paper, a novel network,…

Computer Vision and Pattern Recognition · Computer Science 2019-09-20 Zhen-Liang Ni , Gui-Bin Bian , Xiao-Liang Xie , Zeng-Guang Hou , Xiao-Hu Zhou , Yan-Jie Zhou

Medical image segmentation has played an important role in medical analysis and widely developed for many clinical applications. Deep learning-based approaches have achieved high performance in semantic segmentation but they are limited to…

Image and Video Processing · Electrical Eng. & Systems 2020-12-07 Ngan Le , Trung Le , Kashu Yamazaki , Toan Duc Bui , Khoa Luu , Marios Savides

Medical Image Foundation Models have proven to be powerful tools for mask prediction across various datasets. However, accurately assessing the uncertainty of their predictions remains a significant challenge. To address this, we propose a…

Image and Video Processing · Electrical Eng. & Systems 2025-01-20 Xin Wang , Xiaoyu Liu , Peng Huang , Pu Huang , Shu Hu , Hongtu Zhu
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