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Deep learning techniques have successfully been employed in numerous computer vision tasks including image segmentation. The techniques have also been applied to medical image segmentation, one of the most critical tasks in computer-aided…

Fundoscopic images are often investigated by ophthalmologists to spot abnormal lesions to make diagnoses. Recent successes of convolutional neural networks are confined to diagnoses of few diseases without proper localization of lesion. In…

Learning to segment images purely by relying on the image-text alignment from web data can lead to sub-optimal performance due to noise in the data. The noise comes from the samples where the associated text does not correlate with the…

Accurate segmentation of multiple organs and the differentiation of pathological tissues in medical imaging are crucial but challenging, especially for nuanced classifications and ambiguous organ boundaries. To tackle these challenges, we…

Segmenting anatomical structures such as the photoreceptor layer in retinal optical coherence tomography (OCT) scans is challenging in pathological scenarios. Supervised deep learning models trained with standard loss functions are usually…

Brain lesion and anatomy segmentation in magnetic resonance images are fundamental tasks in neuroimaging research and clinical practice. Given enough training data, convolutional neuronal networks (CNN) proved to outperform all existent…

Since medical image data sets contain few samples and singular features, lesions are viewed as highly similar to other tissues. The traditional neural network has a limited ability to learn features. Even if a host of feature maps is…

We propose a dual-domain cascade of U-nets (i.e. a "W-net") operating in both the spatial frequency and image domains to enhance low-dose CT (LDCT) images without the need for proprietary x-ray projection data. The central slice theorem…

We propose a large-margin Gaussian Mixture (L-GM) loss for deep neural networks in classification tasks. Different from the softmax cross-entropy loss, our proposal is established on the assumption that the deep features of the training set…

Segmenting ultrasound images is critical for various medical applications, but it offers significant challenges due to ultrasound images' inherent noise and unpredictability. To address these challenges, we proposed EUIS-Net, a CNN network…

Melanoma is caused by the abnormal growth of melanocytes in human skin. Like other cancers, this life-threatening skin cancer can be treated with early diagnosis. To support a diagnosis by automatic skin lesion segmentation, several Fully…

When the blood supply to the brain is obstructed by a clot, oxygen delivery to brain tissues becomes insufficient, leading to cellular necrosis. In healthcare settings, accurately identifying and delineating ischemic lesion boundaries is…

Deep neural networks used for reconstructing sparse-view CT data are typically trained by minimizing a pixel-wise mean-squared error or similar loss function over a set of training images. However, networks trained with such pixel-wise…

The accurate understanding of ischemic stroke lesions is critical for efficient therapy and prognosis of stroke patients. Magnetic resonance imaging (MRI) is sensitive to acute ischemic stroke and is a common diagnostic method for stroke.…

We present a new loss function, namely Wing loss, for robust facial landmark localisation with Convolutional Neural Networks (CNNs). We first compare and analyse different loss functions including L2, L1 and smooth L1. The analysis of these…

The segmentation of the retinal vasculature from eye fundus images represents one of the most fundamental tasks in retinal image analysis. Over recent years, increasingly complex approaches based on sophisticated Convolutional Neural…

In many biomedical segmentation tasks, the preservation of elongated structure continuity and length is more important than voxel-wise accuracy. We propose two novel loss functions, Negative Centerline Loss and Simplified Topology Loss,…

Precise characterization of stroke lesions from MRI data has immense value in prognosticating clinical and cognitive outcomes following a stroke. Manual stroke lesion segmentation is time-consuming and requires the expertise of neurologists…

Widely used loss functions for CNN segmentation, e.g., Dice or cross-entropy, are based on integrals over the segmentation regions. Unfortunately, for highly unbalanced segmentations, such regional summations have values that differ by…

We hypothesize that probabilistic voxel-level classification of anatomy and malignancy in prostate MRI, although typically posed as near-identical segmentation tasks via U-Nets, require different loss functions for optimal performance due…