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Variational inference is a popular method for estimating model parameters and conditional distributions in hierarchical and mixed models, which arise frequently in many settings in the health, social, and biological sciences. Variational…

Methodology · Statistics 2019-01-10 Ted Westling , Tyler H. McCormick

Online social networks have dramatically altered the landscape of public discourse, creating both opportunities for enhanced civic participation and risks of deepening social divisions. Prevalent approaches to studying online polarization…

Physics and Society · Physics 2025-06-12 Tim Donkers , Jürgen Ziegler

The presence of intermediate confounders, also called recanting witnesses, is a fundamental challenge to the investigation of causal mechanisms in mediation analysis, preventing the identification of natural path-specific effects. Proposed…

Methodology · Statistics 2024-01-10 Tat-Thang Vo , Nicholas Williams , Richard Liu , Kara E. Rudolph , Ivan Dıaz

Latent factor models that integrate data from multiple sources/studies or modalities have garnered considerable attention across various disciplines. However, existing methods predominantly focus either on multi-study integration or…

Methodology · Statistics 2025-07-15 Wei Liu , Qingzhi Zhong

Variable selection has played a critical role in modern statistical learning and scientific discoveries. Numerous regularization and Bayesian variable selection methods have been developed in the past two decades for variable selection, but…

Methodology · Statistics 2024-03-04 Travis Canida , Hongjie Ke , Shuo Chen , Zhenayo Ye , Tianzhou Ma

A growing literature uses large language models (LLMs) as synthetic participants to generate cost-effective and nearly instantaneous responses in social science experiments. However, there is limited guidance on when such simulations…

Artificial Intelligence · Computer Science 2026-02-18 Jessica Hullman , David Broska , Huaman Sun , Aaron Shaw

Causal inference is central to many areas of artificial intelligence, including complex reasoning, planning, knowledge-base construction, robotics, explanation, and fairness. An active community of researchers develops and enhances…

Artificial Intelligence · Computer Science 2019-11-05 Amanda Gentzel , Dan Garant , David Jensen

Mediation analysis in high-dimensional settings often involves identifying potential mediators among a large number of measured variables. For this purpose, a two-step familywise error rate procedure called ScreenMin has been recently…

Methodology · Statistics 2020-07-07 Vera Djordjilović , Jesse Hemerik , Magne Thoresen

Traditional methods for covariate adjustment of treatment means in designed experiments are inherently conditional on the observed covariate values. In order to develop a coherent general methodology for analysis of covariance, we propose a…

Methodology · Statistics 2010-01-19 James G. Booth , Walter T. Federer , Martin T. Wells , Russell D. Wolfinger

Data from both a randomized trial and an observational study are sometimes simultaneously available for evaluating the effect of an intervention. The randomized data typically allows for reliable estimation of average treatment effects but…

Methodology · Statistics 2021-12-01 David Cheng , Tianxi Cai

Visual analytics systems enable highly interactive exploratory data analysis. Across a range of fields, these technologies have been successfully employed to help users learn from complex data. However, these same exploratory visualization…

Human-Computer Interaction · Computer Science 2021-01-25 Zhilan Zhou , Ximing Wen , Yue Wang , David Gotz

The last decades saw dramatic progress in brain research. These advances were often buttressed by probing single variables to make circumscribed discoveries, typically through null hypothesis significance testing. New ways for generating…

Neurons and Cognition · Quantitative Biology 2019-03-26 Danilo Bzdok , John Ioannidis

Mediation analysis is a form of causal inference that investigates indirect effects and causal mechanisms. Confidence intervals for indirect effects play a central role in conducting inference. The problem is non-standard leading to…

Econometrics · Economics 2024-12-17 Kees Jan van Garderen , Noud van Giersbergen

In high dimensional analysis, effects of explanatory variables on responses sometimes rely on certain exposure variables, such as time or environmental factors. In this paper, to characterize the importance of each predictor, we utilize its…

Methodology · Statistics 2018-04-11 Yeqing Zhou , Jingyuan Liu , Zhihui Hao , Liping Zhu

Causal mediation analysis is widely used to investigate how causal effects operate through specific pathways linking treatments or exposures to outcomes. Recently, \texttt{crumble} was developed to enable nonparametric estimation of several…

Methodology · Statistics 2026-04-14 Richard Liu , Nicholas T. Williams , Kara E. Rudolph , Ivan Diaz

Estimating treatment effects conditional on observed covariates can improve the ability to tailor treatments to particular individuals. Doing so effectively requires dealing with potential confounding, and also enough data to adequately…

Balancing influential covariates is crucial for valid treatment comparisons in clinical studies. While covariate-adaptive randomization is commonly used to achieve balance, its performance can be inadequate when the number of baseline…

Methodology · Statistics 2024-12-30 Ziqing Guo , Yang Liu , Lucy Xia

We propose a causal predictive framework for estimating risk under preventative interventions. The Unexposed Mediator Model maintains mediators that are also predictors at their unexposed level, removing double counting of intervention…

Methodology · Statistics 2026-03-02 Matthew Sperrin , Bowen Jiang , Joyce Huang , Niels Peek , Alexander Pate

Fields like public health, public policy, and social science often want to quantify the degree of dependence between variables whose relationships take on unknown functional forms. Typically, in fact, researchers in these fields are…

Statistics Theory · Mathematics 2019-12-10 Octavio César Mesner , Cosma Rohilla Shalizi

We present a general approach for collaborative filtering (CF) using spectral regularization to learn linear operators from "users" to the "objects" they rate. Recent low-rank type matrix completion approaches to CF are shown to be special…

Machine Learning · Computer Science 2008-12-19 Jacob Abernethy , Francis Bach , Theodoros Evgeniou , Jean-Philippe Vert