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A fitness landscape is a genetic space -- with two genotypes adjacent if they differ in a single locus -- and a fitness function. Evolutionary dynamics produce a flow on this landscape from lower fitness to higher; reaching equilibrium only…

Populations and Evolution · Quantitative Biology 2013-08-26 Artem Kaznatcheev

In this work we develop a microscopic physical model of early evolution, where phenotype,organism life expectancy, is directly related to genotype, the stability of its proteins in their native conformations which can be determined exactly…

Biomolecules · Quantitative Biology 2015-05-13 Konstantin Zeldovich , Peiqiu Chen , Boris Shakhnovich , Eugene Shakhnovich

The fitness of a biological strategy is typically measured by its expected reproductive rate, the first moment of its offspring distribution. However, strategies with high expected rates can also have high probabilities of extinction. A…

Populations and Evolution · Quantitative Biology 2013-05-17 Sterling Sawaya , Steffen Klaere

The concept of fitness is central to evolution, but it quantifies only the expected number of offspring an individual will produce. The actual number of offspring is also subject to noise, arising from environmental or demographic…

Populations and Evolution · Quantitative Biology 2022-09-07 Guocheng Wang , Qi Su , Long Wang , Joshua B. Plotkin

In the context of countable groups of polynomial volume growth, we consider a large class of random walks that are allowed to take long jumps along multiple subgroups according to power law distributions. For such a random walk, we study…

Probability · Mathematics 2022-07-26 Zhen-Qing Chen , Takashi Kumagai , Laurent Saloff-Coste , Jian Wang , Tianyi Zheng

Biological evolution is realised through the same mechanisms of birth and death that underlie change in population density. The deep interdependence between ecology and evolution is well-established, and recent models focus on integrating…

Populations and Evolution · Quantitative Biology 2025-10-14 A. Bradley Duthie , Victor J. Luque

Genetic variation in a population can sometimes arise so fast as to modify ecosystem dynamics. Such phenomena have been observed in natural predator-prey systems, and characterized in the laboratory as showing unusual phase relationships in…

Populations and Evolution · Quantitative Biology 2025-03-25 Hong-Yan Shih , Nigel Goldenfeld

Cooperative behavior is widespread in nature, even though cooperating individuals always run the risk to be exploited by free-riders. Population structure effectively promotes cooperation given that a threshold in the level of cooperation…

Populations and Evolution · Quantitative Biology 2015-06-16 Anna Melbinger , Jonas Cremer , Erwin Frey

Motivated by novel results in the theory of complex adaptive systems, we analyze the dynamics of random walks in which the jumping probabilities are {\it time-dependent}. We determine the survival probability in the presence of an absorbing…

Condensed Matter · Physics 2016-08-31 Shahar Hod

We study the evolutionary dynamics of a maladapted population of self-replicating sequences on strongly correlated fitness landscapes. Each sequence is assumed to be composed of blocks of equal length and its fitness is given by a linear…

Populations and Evolution · Quantitative Biology 2015-05-18 Sarada Seetharaman , Kavita Jain

We present a model for the dynamics of a population of bacteria with a continuum of traits, who compete for resources and exchange horizontally (transfer) an otherwise vertically inherited trait with possible mutations. Competition…

Probability · Mathematics 2017-07-27 Sylvain Billiard , Pierre Collet , Régis Ferrière , Sylvie Méléard , Viet Chi Tran

This work presents a population genetic model of evolution, which includes haploid selection, mutation, recombination, and drift. The mutation-selection equilibrium can be expressed exactly in closed form for arbitrary fitness functions…

Populations and Evolution · Quantitative Biology 2023-02-28 Jenny M. Poulton , Lee Altenberg , Chris Watkins

Generalized Polya urn models can describe the dynamics of finite populations of interacting genotypes. Three basic questions these models can address are: Under what conditions does a population exhibit growth? On the event of growth, at…

Probability · Mathematics 2007-05-23 Michel Benaim , Sebastian J. Schreiber , Pierre Tarres

Evolutionary biology shares many concepts with statistical physics: both deal with populations, whether of molecules or organisms, and both seek to simplify evolution in very many dimensions. Often, methodologies have undergone parallel and…

Populations and Evolution · Quantitative Biology 2015-03-19 Harold P. de Vladar , Nick H. Barton

In evolutionary dynamics, the probability that a mutation spreads through the whole population, having arisen in a single individual, is known as the fixation probability. In general, it is not possible to find the fixation probability…

Populations and Evolution · Quantitative Biology 2010-10-26 Valmir C. Barbosa , Raul Donangelo , Sergio R. Souza

This paper gives conditions for the rightmost particle in the $n$th generation of a multitype branching random walk to have a speed, in the sense that its location divided by n converges to a constant as n goes to infinity. Furthermore, a…

Probability · Mathematics 2012-10-17 J. D. Biggins

We consider a branching random walk in a random space-time environment of disasters where each particle is killed when meeting a disaster. This extends the model of the "random walk in a disastrous random environment" introduced by [15]. We…

Probability · Mathematics 2017-09-13 Nina Gantert , Stefan Junk

We give a simple statistical proof of a binomial identity, by evaluating the Laplace transform of the maximum of n independent exponential random variables in two different ways. As a by product, we obtain a simple proof of an interesting…

Statistics Theory · Mathematics 2014-08-19 P. Vellaisamy

Epochal dynamics, in which long periods of stasis in an evolving population are punctuated by a sudden burst of change, is a common behavior in both natural and artificial evolutionary processes. We analyze the population dynamics for a…

adap-org · Physics 2007-05-23 Erik van Nimwegen , James P. Crutchfield

Kingman's model describes the evolution of a one-locus haploid population of infinite size and discrete generations under the competition of selection and mutation. A random generalisation has been made in a previous paper which assumes all…

Probability · Mathematics 2020-12-01 Linglong Yuan
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