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Related papers: An Inductive Logic Programming Approach to Validat…

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Recent years have seen a surge of interest in Probabilistic Logic Programming (PLP) and Statistical Relational Learning (SRL) models that combine logic with probabilities. Structure learning of these systems is an intersection area of…

Machine Learning · Computer Science 2014-02-26 Wang-Zhou Dai , Zhi-Hua Zhou

Protein language models (PLMs) have revolutionised computational biology through their ability to generate powerful sequence representations for diverse prediction tasks. However, their black-box nature limits biological interpretation and…

Biomolecules · Quantitative Biology 2025-04-11 Jan van Eck , Dea Gogishvili , Wilson Silva , Sanne Abeln

Proteins play crucial roles in every cellular process by interacting with each other, with nucleic acids, metabolites, and other molecules. The resulting assemblies can be very large and intricate and pose challenges to experimental…

Biomolecules · Quantitative Biology 2021-03-16 Charlotte W. van Noort , Rodrigo V. Honorato , Alexandre M. J. J. Bonvin

The goal of inductive logic programming (ILP) is to find a set of logical rules that generalises training examples and background knowledge. We introduce an ILP approach that identifies pointless rules. A rule is pointless if it contains a…

Artificial Intelligence · Computer Science 2026-01-26 Andrew Cropper , David M. Cerna

Protein sequences are abundant in repeating segments, both as exact copies and as approximate segments with mutations. These repeats are important for protein structure and function, motivating decades of algorithmic work on repeat…

Machine Learning · Computer Science 2026-05-26 Gal Pomerants , Yaniv Nikankin , Anja Reusch , Tomer Tsaban , Ora Schueler-Furman , Yonatan Belinkov

One approach to explaining the hierarchical levels of understanding within a machine learning model is the symbolic method of inductive logic programming (ILP), which is data efficient and capable of learning first-order logic rules that…

Machine Learning · Computer Science 2023-09-01 Andreas Bueff , Vaishak Belle

Biomedical knowledge graphs permit an integrative computational approach to reasoning about biological systems. The nature of biological data leads to a graph structure that differs from those typically encountered in benchmarking datasets.…

Machine Learning · Computer Science 2021-03-19 Yushan Liu , Marcel Hildebrandt , Mitchell Joblin , Martin Ringsquandl , Rime Raissouni , Volker Tresp

Hypothesis ranking is vital for automated scientific discovery, especially in cost-intensive, throughput-limited natural science domains. Current methods focus on pre-experiment ranking, relying solely on language model reasoning without…

Computation and Language · Computer Science 2025-10-28 Wanhao Liu , Zonglin Yang , Jue Wang , Lidong Bing , Di Zhang , Dongzhan Zhou , Yuqiang Li , Houqiang Li , Erik Cambria , Wanli Ouyang

Experience in the physical sciences suggests that the only realistic means of understanding complex systems is through the use of mathematical models. Typically, this has come to mean the identification of quantitative models expressed as…

Artificial Intelligence · Computer Science 2011-11-02 George M. Coghill , Ross D. King , Ashwin Srinivasan

This work presents a novel systematic methodology to analyse the capabilities and limitations of Large Language Models (LLMs) with feedback from a formal inference engine, on logic theory induction. The analysis is complexity-graded w.r.t.…

Computation and Language · Computer Science 2025-01-15 João Pedro Gandarela , Danilo S. Carvalho , André Freitas

We describe the Inspire system which participated in the first competition on Inductive Logic Programming (ILP). Inspire is based on Answer Set Programming (ASP). The distinguishing feature of Inspire is an ASP encoding for hypothesis space…

Artificial Intelligence · Computer Science 2018-02-27 Peter Schüller , Mishal Benz

The goal of inductive logic programming (ILP) is to search for a logic program that generalises training examples and background knowledge. We introduce an ILP approach that identifies minimal unsatisfiable subprograms (MUSPs). We show that…

Machine Learning · Computer Science 2024-01-30 Andrew Cropper , Céline Hocquette

We describe an inductive logic programming (ILP) approach called learning from failures. In this approach, an ILP system (the learner) decomposes the learning problem into three separate stages: generate, test, and constrain. In the…

Artificial Intelligence · Computer Science 2020-11-26 Andrew Cropper , Rolf Morel

Scientists form hypotheses and experimentally test them. If a hypothesis fails (is refuted), scientists try to explain the failure to eliminate other hypotheses. The more precise the failure analysis the more hypotheses can be eliminated.…

Artificial Intelligence · Computer Science 2023-05-25 Rolf Morel , Andrew Cropper

An important application of Synthetic Biology is the engineering of the host cell system to yield useful products. However, an increase in the scale of the host system leads to huge design space and requires a large number of validation…

Artificial Intelligence · Computer Science 2023-09-04 Lun Ai , Shi-Shun Liang , Wang-Zhou Dai , Liam Hallett , Stephen H. Muggleton , Geoff S. Baldwin

The paradigm that the primary amino acid sequence prescribes structure and thus function has for a long time been central to the understanding of protein science. Though the theory is supported by the behaviour of most structured proteins,…

Biological Physics · Physics 2022-12-19 Rickie Xian , Sarah Rauscher

Learning rules plays a crucial role in deep learning, particularly in explainable artificial intelligence and enhancing the reasoning capabilities of large language models. While existing rule learning methods are primarily designed for…

Artificial Intelligence · Computer Science 2026-04-10 Kun Gao , Davide Soldà , Thomas Eiter , Katsumi Inoue

Probabilistic Inductive Logic Programming (PILP) is a rel- atively unexplored area of Statistical Relational Learning which extends classic Inductive Logic Programming (ILP). This work introduces SkILL, a Stochastic Inductive Logic Learner,…

Artificial Intelligence · Computer Science 2015-06-03 Joana Côrte-Real , Theofrastos Mantadelis , Inês Dutra , Ricardo Rocha

Cells regulate themselves via dizzyingly complex biochemical processes called signaling pathways. These are usually depicted as a network, where nodes represent proteins and edges indicate their influence on each other. In order to…

Molecular Networks · Quantitative Biology 2021-01-13 David Merrell , Anthony Gitter

HEX-programs are an extension of answer set programs (ASP) with external sources. To this end, external atoms provide a bidirectional interface between the program and an external source. The traditional evaluation algorithm for…

Artificial Intelligence · Computer Science 2020-02-19 Christoph Redl